Prescription drug abuse is a pressing public health issue, and people who misuse prescription drugs are turning to online forums for help. Are such forums effective? We analyze the process of opioid withdrawal, recovery and relapse on Forum77, MedHelp.org's online health forum for substance abuse recovery. Applying Prochashka's Transtheoretical Model for behavior change, we develop a taxonomy describing phases of addiction expressed by Forum77 members. We examine activity and linguistic features across the phases USING, WITHDRAWING and RECOVERING. We train statistical classifiers to identify addiction phase, relapse and whether a user was RECOVERING at the time of her last post. Applying our classifiers to 2,848 users, we find that while almost 50% relapse, the prognosis for ending in RECOVERING is favorable. Supplementing our results with users' own accounts of their experiences, we discuss Forum77's efficacy and shortcomings, and implications for future technologies.

Thousands of people use the Internet to discuss pain symptoms. While communication between patients and physicians involves both verbal and physical interactions, online discussions of symptoms typically comprise text only. We present BodyDiagrams, an online interface for expressing symptoms via drawings and text. BodyDiagrams augment textual descriptions with pain diagrams drawn over a reference body and annotated with severity and temporal metadata. The resulting diagrams can easily be shared to solicit feedback and advice. We also conduct a two-phase user study to assess BodyDiagrams' communicative efficacy. In the first phase, users describe pain symptoms using BodyDiagrams and a text-only interface; in the second phase, medical professionals evaluate these descriptions. We find that patients are significantly more confident that their BodyDiagrams will be correctly interpreted, while medical professionals rated BodyDiagrams as significantly more informative than text descriptions. Both groups indicated a preference for using diagrams to communicate physical symptoms in the future.

OBJECTIVE: To reliably extract two entity types, symptoms and conditions (SCs), and drugs and treatments (DTs), from patient-authored text (PAT) by learning lexico-syntactic patterns from data annotated with seed dictionaries. BACKGROUND AND SIGNIFICANCE: Despite the increasing quantity of PAT (eg, online discussion threads), tools for identifying medical entities in PAT are limited. When applied to PAT, existing tools either fail to identify specific entity types or perform poorly. Identification of SC and DT terms in PAT would enable exploration of efficacy and side effects for not only pharmaceutical drugs, but also for home remedies and components of daily care. MATERIALS AND METHODS: We use SC and DT term dictionaries compiled from online sources to label several discussion forums from MedHelp (http://www.medhelp.org). We then iteratively induce lexico-syntactic patterns corresponding strongly to each entity type to extract new SC and DT terms. RESULTS: Our system is able to extract symptom descriptions and treatments absent from our original dictionaries, such as 'LADA', 'stabbing pain', and 'cinnamon pills'. Our system extracts DT terms with 58-70% F1 score and SC terms with 66-76% F1 score on two forums from MedHelp. We show improvements over MetaMap, OBA, a conditional random field-based classifier, and a previous pattern learning approach. CONCLUSIONS: Our entity extractor based on lexico-syntactic patterns is a successful and preferable technique for identifying specific entity types in PAT. To the best of our knowledge, this is the first paper to extract SC and DT entities from PAT. We exhibit learning of informal terms often used in PAT but missing from typical dictionaries.

This paper presents novel human computation experiments geared towards uncovering the structure of affect. Using Mechanical Turk workers across 2 separate studies, we empirically verified some of the popular beliefs about the structure of affect, but also provide some new evidence. We replicate and reveal not only the statistical structure of the dimensions of affect, but also the effect of cultural influences. We close with a proposition for a framework for doing this kind of large scale research and provide recommendations and opportunities for innovations in research around emotional theory.

BACKGROUND AND OBJECTIVE: As people increasingly engage in online health-seeking behavior and contribute to health-oriented websites, the volume of medical text authored by patients and other medical novices grows rapidly. However, we lack an effective method for automatically identifying medical terms in patient-authored text (PAT). We demonstrate that crowdsourcing PAT medical term identification tasks to non-experts is a viable method for creating large, accurately-labeled PAT datasets; moreover, such datasets can be used to train classifiers that outperform existing medical term identification tools. MATERIALS AND METHODS: To evaluate the viability of using non-expert crowds to label PAT, we compare expert (registered nurses) and non-expert (Amazon Mechanical Turk workers; Turkers) responses to a PAT medical term identification task. Next, we build a crowd-labeled dataset comprising 10 000 sentences from MedHelp. We train two models on this dataset and evaluate their performance, as well as that of MetaMap, Open Biomedical Annotator (OBA), and NaCTeM's TerMINE, against two gold standard datasets: one from MedHelp and the other from CureTogether. RESULTS: When aggregated according to a corroborative voting policy, Turker responses predict expert responses with an F1 score of 84%. A conditional random field (CRF) trained on 10 000 crowd-labeled MedHelp sentences achieves an F1 score of 78% against the CureTogether gold standard, widely outperforming OBA (47%), TerMINE (43%), and MetaMap (39%). A failure analysis of the CRF suggests that misclassified terms are likely to be either generic or rare. CONCLUSIONS: Our results show that combining statistical models sensitive to sentence-level context with crowd-labeled data is a scalable and effective technique for automatically identifying medical terms in PAT.

Visual methods for supporting the characterization, comparison, and classification of large networks remain an open challenge. Ideally, such techniques should surface useful structural features -- such as effective diameter, small-world properties, and structural holes -- not always apparent from either summary statistics or typical network visualizations. In this paper, we present GraphPrism, a technique for visually summarizing arbitrarily large graphs through combinations of 'facets', each corresponding to a single node- or edge-specific metric (e.g., transitivity). We describe a generalized approach for constructing facets by calculating distributions of graph metrics over increasingly large local neighborhoods and representing these as a stacked multi-scale histogram. Evaluation with paper prototypes shows that, with minimal training, static GraphPrism diagrams can aid network analysis experts in performing basic analysis tasks with network data. Finally, we contribute the design of an interactive system using linked selection between GraphPrism overviews and node-link detail views. Using a case study of data from a co-authorship network, we illustrate how GraphPrism facilitates interactive exploration of network data.

As people accumulate hundreds of "friends" in social media, a flat list of connections becomes unmanageable. Interfaces agnostic to social structure hinder the nuanced sharing of personal data such as photos, status updates, news feeds, and comments. To address this problem, we propose social topologies, a set of potentially overlapping and nested social groups, that represent the structure and content of a person's social network as a first-class object. We contribute an algorithm for creating social topologies by mining communication history and identifying likely groups based on co-occurrence patterns. We use our algorithm to populate a browser interface that supports creation and editing of social groups via direct manipulation. A user study confirms that our approach models subjects' social topologies well, and that our interface enables intuitive browsing and management of a personal social landscape.