Accurate correspondence matching in coronary angiography images is crucial for reconstructing 3D coronary artery structures, which is essential for precise diagnosis and treatment planning of coronary artery disease (CAD). Traditional matching methods for natural images often fail to generalize to X-ray images due to inherent differences such as lack of texture, lower contrast, and overlapping structures, compounded by insufficient training data. To address these challenges, we propose a novel pipeline that generates realistic paired coronary angiography images using a diffusion model conditioned on 2D projections of 3D reconstructed meshes from Coronary Computed Tomography Angiography (CCTA), providing high-quality synthetic data for training. Additionally, we employ large-scale image foundation models to guide feature aggregation, enhancing correspondence matching accuracy by focusing on semantically relevant regions and keypoints. Our approach demonstrates superior matching performance on synthetic datasets and effectively generalizes to real-world datasets, offering a practical solution for this task. Furthermore, our work investigates the efficacy of different foundation models in correspondence matching, providing novel insights into leveraging advanced image foundation models for medical imaging applications.

The accurate segmentation of guidewires in interventional cardiac fluoroscopy videos is crucial for computer-aided navigation tasks. Although deep learning methods have demonstrated high accuracy and robustness in wire segmentation, they require substantial annotated datasets for generalizability, underscoring the need for extensive labeled data to enhance model performance. To address this challenge, we propose the Segmentation-guided Frame-consistency Video Diffusion Model (SF-VD) to generate large collections of labeled fluoroscopy videos, augmenting the training data for wire segmentation networks. SF-VD leverages videos with limited annotations by independently modeling scene distribution and motion distribution. It first samples the scene distribution by generating 2D fluoroscopy images with wires positioned according to a specified input mask, and then samples the motion distribution by progressively generating subsequent frames, ensuring frame-to-frame coherence through a frame-consistency strategy. A segmentation-guided mechanism further refines the process by adjusting wire contrast, ensuring a diverse range of visibility in the synthesized image. Evaluation on a fluoroscopy dataset confirms the superior quality of the generated videos and shows significant improvements in guidewire segmentation.

Medical image segmentation is crucial for clinical decision-making, but the scarcity of annotated data presents significant challenges. Few-shot segmentation (FSS) methods show promise but often require training on the target domain and struggle to generalize across different modalities. Similarly, adapting foundation models such as the segment anything model (SAM) for medical imaging has limitations, including the need for fine-tuning and domain-specific adaptation. To address these issues, we propose a novel method that adapts DINOv2 and SAM 2 for retrieval-augmented few-shot medical image segmentation. Our approach uses DINOv2's feature as query to retrieve similar samples from limited annotated data, which are then encoded as memories and stored in memory bank. With the memory attention mechanism of SAM 2, the model leverages these memories as conditions to generate accurate segmentation of the target image. We evaluated our framework on three medical image segmentation tasks, demonstrating superior performance and generalizability across various modalities without the need for any retraining or fine-tuning. Overall, this method offers a practical and effective solution for few-shot medical image segmentation and holds significant potential as a valuable annotation tool in clinical applications.

In this paper, the observer based neural adaptive finite-time containment control strategy for non-strict feedback nonlinear multi-agent systems is studied. The finite-time command filter is used to overcome the explosion of complexity problem and the established fractional power based error compensation signal is applied to compensate the filtering error caused by the filter. The distributed finite-time command filtered backstepping control method combines with the neural adaptive control technology and state observer is given, which ensures the containment control errors reach to the desired neighborhood of the origin in finite-time in the presence of uncertain dynamics and unmeasurable states in the system. The given numerical simulations show the effectiveness of the proposed control strategy.

Fast and accurate MRI image reconstruction from undersampled data is crucial in clinical practice. Deep learning based reconstruction methods have shown promising advances in recent years. However, recovering fine details from undersampled data is still challenging. In this paper, we introduce a novel deep learning based method, Pyramid Convolutional RNN (PC-RNN), to reconstruct images from multiple scales. Based on the formulation of MRI reconstruction as an inverse problem, we design the PC-RNN model with three convolutional RNN (ConvRNN) modules to iteratively learn the features in multiple scales. Each ConvRNN module reconstructs images at different scales and the reconstructed images are combined by a final CNN module in a pyramid fashion. The multi-scale ConvRNN modules learn a coarse-to-fine image reconstruction. Unlike other common reconstruction methods for parallel imaging, PC-RNN does not employ coil sensitive maps for multi-coil data and directly model the multiple coils as multi-channel inputs. The coil compression technique is applied to standardize data with various coil numbers, leading to more efficient training. We evaluate our model on the fastMRI knee and brain datasets and the results show that the proposed model outperforms other methods and can recover more details. The proposed method is one of the winner solutions in the 2019 fastMRI competition.

Motion estimation of cardiac MRI videos is crucial for the evaluation of human heart anatomy and function. Recent researches show promising results with deep learning-based methods. In clinical deployment, however, they suffer dramatic performance drops due to mismatched distributions between training and testing datasets, commonly encountered in the clinical environment. On the other hand, it is arguably impossible to collect all representative datasets and to train a universal tracker before deployment. In this context, we proposed a novel fast online adaptive learning (FOAL) framework: an online gradient descent based optimizer that is optimized by a meta-learner. The meta-learner enables the online optimizer to perform a fast and robust adaptation. We evaluated our method through extensive experiments on two public clinical datasets. The results showed the superior performance of FOAL in accuracy compared to the offline-trained tracking method. On average, the FOAL took only 0.4 second per video for online optimization.

Denoising is an indispensable step in processing low-dose X-ray fluoroscopic images that requires development of specialized high-quality algorithms able to operate in near real-time. We address this problem with an efficient deep learning approach based on the process-centric view of traditional iterative thresholding methods. We develop a novel trainable patch-based multiscale framework for sparse image representation. In a computationally efficient way, it allows us to accurately reconstruct important image features on multiple levels of decomposition with patch dictionaries of reduced size and complexity. The flexibility of the chosen machine learning approach allows us to tailor the learned basis for preserving important structural information in the image and noticeably minimize the amount of artifacts. Our denoising results obtained with real clinical data demonstrate significant quality improvement and are computed much faster in comparison with the BM3D algorithm.