Abstract Summary: EDGE (Extraction of Differential Gene Expression) is an open source, point-and-click software program for the significance analysis of DNA microarray experiments. EDGE can perform both standard and time course differential expression analysis. The functions are based on newly developed statistical theory and methods. This document introduces the EDGE software package. Availability: EDGE is freely available for non-commercial users. EDGE can be downloaded for Windows, Macintosh and Linux/UNIX from Contact: [email protected]

The authors would like to apologise for the omission of John D. Storey's email address, as he is a corresponding author for the article. He can be contacted by [email protected]. The authors would also like to apologise for an incorrect reference given in the article. The reference cited by Storey et al. (2005b) should be as follows: Storey,J.D. et al. (2005b) Significance analysis of time course microarray experiments. Proc. Natl Acad. Sci. USA, 102, 12837–12842.