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Abel Rodríguez

dblp:12/8713 · DBLP profile ↗
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4ranked-venue papers
0as first author
0since 2021 · last 2016
0000-0001-5503-7394ORCID · corroborated

Domains — the database's venue-derived domains; a paper can count in several

Computer networks · 2Applied, interdisciplinary, general and emerging computing · 2

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
1 paper
Bioinformatics and computational biology · 100%

Topics — the 2 heaviest of 3, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Bioinformatics and computational biology
molecular evolution
0.112010
Characterizing molecular adaptation: a hierarchical approach to assess the selective influence of amino acid properties · Bioinform. 2010
Bioinformatics and computational biology › population genetics › selection detection
positive selection detection
0.112010
Characterizing molecular adaptation: a hierarchical approach to assess the selective influence of amino acid properties · Bioinform. 2010

Methods — techniques the papers use, named apart from their topics

multiple comparison adjustment · 0.1bayesian hierarchical model · 0.1
YearPublicationVenuePosition
2016 Characterizing User Activity in WiFi Networks: University Campus and Urban Area Case Studies
abstract
In this paper we investigate and characterize user activity in WiFi networks by analyzing and comparing the behavior of users that connect to two public WiFi networks, one of them deployed in a University campus and the other in a major urban area. We characterize WiFi network user activity based on two main features, namely: time users stay connected to Access Points and Access Point load. Overall, the main contributions of our work are as follows: (1) to the best of our knowledge, this is the first study comparing user activity in two different scenarions, i.e., a University campus WiFi network and an urban WiFi network; (2) our results validate previously observed characteristics of user behavior in WiFi networks, as well as unveil new behavior patterns, such as the fact that users on campus tend to stay connected to the network for longer periods of time when compared to users in an urban area; and (3) our work is the first study to formally test and validate the hypothesis that association times in WiFi networks follows a power law and to estimate the power-law's tail index.
Katia Obraczka, Abel Rodríguez
MSWiM3
2012 SAGA: socially- and geography-aware mobility modeling framework
abstract
In this paper, we introduce a user mobility modeling framework that accounts for both the users' social structure as well as the geographic diversity of the region of interest. SAGA, or Socially- and Geography-Aware mobility model, captures social features through the use of communities which cluster users with similar features such as average time in a cell, average speed, and pause time. SAGA accounts for geographic diversity by considering that different communities exhibit different interests for different locales; therefore, different communities are attracted to certain physical locations with different intensities. Besides introducing SAGA, the contributions of this work include: a model calibration approach based on formal statistical procedures to extract social structures and geographical diversity from real traces and set SAGA's parameters; and validation of SAGA by applying it to real mobility traces. Our experimental results show that, when compared to existing mobility regimes such as Random-Waypoint and Preferential-Attachment based mobility, SAGA is able to preserve the desired non-uniform node spatial density present in real user mobility, creating and maintaining clusters and accounting for differential node popularity and transitivity.
Bruno Astuto A. Nunes, Katia Obraczka, Abel Rodríguez
MSWiM3
2012 Bayesian Semiparametric Regression Models to Characterize Molecular Evolution
abstract
BACKGROUND: Statistical models and methods that associate changes in the physicochemical properties of amino acids with natural selection at the molecular level typically do not take into account the correlations between such properties. We propose a Bayesian hierarchical regression model with a generalization of the Dirichlet process prior on the distribution of the regression coefficients that describes the relationship between the changes in amino acid distances and natural selection in protein-coding DNA sequence alignments. RESULTS: The Bayesian semiparametric approach is illustrated with simulated data and the abalone lysin sperm data. Our method identifies groups of properties which, for this particular dataset, have a similar effect on evolution. The model also provides nonparametric site-specific estimates for the strength of conservation of these properties. CONCLUSIONS: The model described here is distinguished by its ability to handle a large number of amino acid properties simultaneously, while taking into account that such data can be correlated. The multi-level clustering ability of the model allows for appealing interpretations of the results in terms of properties that are roughly equivalent from the standpoint of molecular evolution.
Saheli Datta, Abel Rodríguez, Raquel Prado
BMC Bioinform.2
2010 Characterizing molecular adaptation: a hierarchical approach to assess the selective influence of amino acid properties
abstract
MOTIVATION: A number of methods for detecting positive selection in protein coding DNA sequences are based on whether each site/region has a non-synonymous to synonymous substitution rates ratio ω greater than one. However, a site/region may show a relatively large number of non-synonymous mutations that conserve a particular property. Recent methods have proposed to consider as evidence for molecular adaptations how conserving, or radically different, non-synonymous mutations are with respect to some key amino acid properties. While such methods have been useful in providing a qualitative assessment of molecular adaptation, they rely on independent statistical analyses for each amino acid property and typically do not properly adjust for multiple comparisons when selection needs to be assessed at several sites. RESULTS: We consider a Bayesian hierarchical model that allows us to jointly determine if a set of amino acid properties are being conserved or radically changed while simultaneously adjusting for multiple comparisons at the codon level. We illustrate how this model can be used to characterize molecular adaptation in two datasets: an alignment from six class I alleles of the human major histocompatibility complex and a sperm lysin alignment from 25 abalone species. We compare the results obtained with the proposed hierarchical models to those obtained with alternative methods. Our analyses indicate that a more complete quantitative and qualitative characterization of molecular adaptation is achieved by taking into account changes in amino acid properties. AVAILABILITY: The R code for implementing the hierarchical models is freely available at http://www.ams.ucsc.edu/∼raquel/software/.
Saheli Datta, Raquel Prado, Abel Rodríguez, Ananías A. Escalante
Bioinform.3