With the widespread use of location-tracking technologies, large volumes of trajectory data are continuously generated. Trajectory similarity computation is a core task in trajectory mining with broad applications. However, existing methods still face two key challenges: (1) the difficulty of balancing efficiency and representation quality, and (2) the reliance on a single training paradigm, which limits the ability to capture both pairwise similarity and batch-level coherence. To address these challenges, we propose a trajectory similarity computation framework named TrajAgg. Specifically, our framework incorporates a novel Aggregation Transformer that efficiently aggregates GPS and grid features through two stages of direct interaction and enhances the expressiveness of the resulting trajectory embeddings. In addition, by integrating two distinct training paradigms, our model captures both fine-grained pairwise relationships and global structural consistency. We further analyze its effectiveness from the perspective of mutual information. Extensive experiments on three publicly available datasets show that TrajAgg consistently outperforms state-of-the-art baselines. Our method achieves average improvements of 15.11%, 16.49%, 10.41%, and 40.15% in HR@1 under four distance measures across three datasets, respectively.

Trajectory similarity computation plays a critical role in a wide range of trajectory-related applications, including transportation optimization and behavior study. Most studies aim at learning discriminative real-valued trajectory representations. However, these methods struggle to scale to large datasets due to their linear time complexity. To address this problem, only one hypergraph hash learning approach (HHL-Traj) has been proposed to realize efficient trajectory similarity computation by calculating Hamming distances among the trajectory hash codes. Nevertheless, it fails to effectively integrate the spatial and temporal information of trajectory data with semantic relevance. In this paper, we present a novel Trajectory Similarity Hash Learning method with Spatio-Temporal GRU (TrajH-ST), which fuses the spatial and temporal features through reset and update gates within the network architecture. Additionally, we design an alternating sampling strategy to generate two sub-trajectories for contrastive learning, which enhances both generalization and robustness compared to nonuniform sampling techniques. To optimize the proposed end-to-end model, we develop an objective function that incorporates InfoNCE loss, alignment loss, and quantization loss. Extensive experiments on two widely-used trajectory datasets demonstrate that the proposed model consistently outperforms state-of-the-art baselines, achieving accuracy improvements of up to 5.58% and 4.33% with real-valued and binary features, respectively. Our code is available athttps://github.com/caoyuan618/Traj-ST

Traffic prediction is critical for optimizing travel scheduling and enhancing public safety, yet the complex spatial and temporal dynamics within traffic data present significant challenges for accurate forecasting. In this paper, we introduce a novel model, the Spatiotemporal-aware Trend-Seasonality Decomposition Network (STDN). This model begins by constructing a dynamic graph structure to represent traffic flow and incorporates novel spatio-temporal embeddings to jointly capture global traffic dynamics. The representations learned are further refined by a specially designed trend-seasonality decomposition module, which disentangles the trend-cyclical component and seasonal component for each traffic node at different times within the graph. These components are subsequently processed through an encoder-decoder network to generate the final predictions. Extensive experiments conducted on real-world traffic datasets demonstrate that STDN achieves superior performance with remarkable computation cost. Furthermore, we have released a new traffic dataset named JiNan, which features unique inner-city dynamics, thereby enriching the scenario comprehensiveness in traffic prediction evaluation.

Medical Large Vision-Language Models (MLVLMs) show encouraging results in medical diagnostics but easily in-herit biases from pretraining data, leading to bias catastrophic inheritance, where data biases persist and distort predictions. In this work, we present the first systematic study of this issue in MLVLMs, revealing how inherited biases affect classification and free-text reasoning tasks. We propose Logit Fairness Adjustment (LFA), a training-free debiasing method that operates at the logits level to recalibrate biased predictions. LFA quantifies bias by computing logit margins between valid and invalid medical images, applying logit smoothing when the margin is small to reduce overconfidence and bias compensation when the margin is large to reinforce valid features. We introduce the Medical Multimodal Bias Benchmark to assess bias severity across binary classification, multi-class classification, and free-text reasoning. Experiments on LLaVA-Med, SkinGPT-4, and Qwen-VL-7B show that LFA effectively mitigates bias for MLVLMs.

Deep learning-based approaches have demonstrated significant advancements in time series forecasting. Despite these ongoing developments, the complex dynamics of time series make it challenging to establish the rule of thumb for designing the golden model architecture. In this study, we argue that refining existing advanced models through a universal calibrating strategy can deliver substantial benefits with minimal resource costs, as opposed to elaborating and training a new model from scratch. We first identify a multi-target learning conflict in the calibrating process, which arises when optimizing variables across time steps, leading to the underutilization of the model's learning capabilities. To address this issue, we propose an innovative calibrating strategy called Socket+Plug (SoP). This approach retains an exclusive optimizer and early-stopping monitor for each predicted target within each Plug while keeping the fully trained Socket backbone frozen. The model-agnostic nature of SoP allows it to directly calibrate the performance of any trained deep forecasting models, regardless of their specific architectures. Extensive experiments on various time series benchmarks and a spatio-temporal meteorological ERA5 dataset demonstrate the effectiveness of SoP, achieving up to a 22% improvement even when employing a simple MLP as the Plug (highlighted in Figure 1).

Multivariate time series forecasting is a critical focus across many fields. Existing transformer-based models have overlooked the explicit modeling of inter-variable correlations. Similarly, the graph-based methods have also failed to address the dynamic nature of multivariate correlations and the noise in correlation modeling. To overcome these challenges, we propose a novel Dynamic Graph Learning Guided Multi-Scale Transformer (DGraFormer) for multivariate time series forecasting. Specifically, our method consists of two main components: Dynamic correlation-aware graph Learning (DCGL) and multi-scale temporal transformer (MTT). The former aims to capture dynamic correlations across different time windows, filters out noise, and selects key weights to guide the aggregation of relevant feature representations. The latter can effectively extract temporal patterns from patch data at varying scales. Finally, the proposed method can capture rich local correlation graph structures and multi-scale global temporal features. Experimental results demonstrate that DGraformer significantly outperforms existing state-of-the-art models on ten real-world datasets, achieving the best performance across multiple evaluation metrics. The source code of our model is available at \url{https://anonymous.4open.science/r/DGraFormer}.

Weather forecasting is of great importance for human life and various real-world fields, e.g., traffic prediction, agricultural production, and tourist industry. Existing methods can be roughly divided into two categories: theory-driven (e.g., numerical weather prediction (NWP)) and data-driven methods. Theory-driven methods require a complex simulation of the physical evolution process in the atmosphere model using supercomputers, while most data-driven methods learn the underlying laws from the historical weather records via deep learning models. However, some data-driven methods simply regard all weather variables of monitoring stations as a whole and fail to more granularly exploit complex correlations across different stations, while others prefer to construct large neural networks with massive learnable parameters. To alleviate these defects, we propose a spatio-temporal contrastive self-supervision method and a generative contextual self-supervised technique to capture spatial and temporal dependencies from the station-level and variable-level, respectively. Through these well-designed self-supervised tasks, uncomplicated networks obtain strong capability to capture latent representations for weather changes with time-varying. Thereafter, an effective encoder-decoder based fine-tuning framework is proposed, consisting of three self-supervised encoders. Extensive experiments conducted on four real-world weather condition datasets demonstrate that our method outperforms the state-of-the-art models and also empirically validates the feasibility of each self-supervised task.

Next location recommendation plays an important role in various location-based services, yielding great value for both users and service providers. Existing methods usually model temporal dependencies with explicit time intervals or learn representation from customized point of interest (POI) graphs with rich context information to capture the sequential patterns among POIs. However, this problem is perceptibly complex, because various factors, e.g., users’ preferences, spatial locations, time contexts, activity category semantics, and temporal relations, need to be considered together, while most studies lack sufficient consideration of the collaborative signals. Toward this goal, we propose a novel M ulti-Level C ollaborative Neural N etwork for next location Rec ommendation (MCN4Rec). Specifically, we design a multi-level view representation learning with level-wise contrastive learning to collaboratively learn representation from local and global perspectives to capture complex heterogeneous relationships among user, POI, time, and activity categories. Then, a causal encoder-decoder is applied to the learned representations of check-in sequences to recommend the next location. Extensive experiments on four real-world check-in mobility datasets demonstrate that our model significantly outperforms the existing state-of-the-art baselines for the next location recommendation. Ablation study further validates the benefits of the collaboration of the designed sub-modules. The source code is available at https://github.com/quai-mengxiang/MCN4Rec .

MOTIVATION: Hi-C technology has been the most widely used chromosome conformation capture (3C) experiment that measures the frequency of all paired interactions in the entire genome, which is a powerful tool for studying the 3D structure of the genome. The fineness of the constructed genome structure depends on the resolution of Hi-C data. However, due to the fact that high-resolution Hi-C data require deep sequencing and thus high experimental cost, most available Hi-C data are in low-resolution. Hence, it is essential to enhance the quality of Hi-C data by developing the effective computational methods. RESULTS: In this work, we propose a novel method, so-called DFHiC, which generates the high-resolution Hi-C matrix from the low-resolution Hi-C matrix in the framework of the dilated convolutional neural network. The dilated convolution is able to effectively explore the global patterns in the overall Hi-C matrix by taking advantage of the information of the Hi-C matrix in a way of the longer genomic distance. Consequently, DFHiC can improve the resolution of the Hi-C matrix reliably and accurately. More importantly, the super-resolution Hi-C data enhanced by DFHiC is more in line with the real high-resolution Hi-C data than those done by the other existing methods, in terms of both chromatin significant interactions and identifying topologically associating domains. AVAILABILITY AND IMPLEMENTATION: https://github.com/BinWangCSU/DFHiC.

As a frontier field of individualized therapy, microRNA (miRNA) pharmacogenomics facilitates the understanding of different individual responses to certain drugs and provides a reasonable reference for clinical treatment. However, the known drug resistance-associated miRNAs are not yet sufficient to support precision medicine. Although existing methods are effective, they all focus on modelling miRNA-drug resistance interaction graphs, making their performance bounded by the interaction density. In this study, we propose a framework for miRNA-drug resistance prediction through efficient neural architecture search and graph isomorphism networks (NASMDR). NASMDR uses attribute information instead of the commonly used interactive graph information. In the cross-validation experiment, the proposed framework can achieve an AUC of 0.9468 on the ncDR dataset, which is 2.29% higher than the state-of-the-art method. In addition, we propose a novel sequence characterization approach, k-mer Sparse Nonnegative Matrix Factorization (KSNMF). The results show that NASMDR provides novel insights for integrating efficient neural architecture search and graph isomorphic networks into a unified framework to predict drug resistance-related miRNAs. The codes for NASMDR are available at https://github.com/kaizheng-academic/NASMDR.

When a train leaves a platform, knowing the carriage load (the number of passengers in each carriage) of this train will support train managers to guide passengers at the next platform to choose carriages to avoid congestion. This capacity has become critical since the onset of the pandemic. However, with the dynamicity of passengers and the speed of trains improved (about 3 minutes travel between stations) as well as the station stop period reduced (60–90 second per station), the real-time prediction is more challenging. This paper presents an intelligent system, which is developed in collaboration with Sydney Trains, for real-time predicting carriage load across a city passenger train network. The system comprises three innovations. First, a fuzzy time-matching method significantly improves prediction accuracy in the uncertain situations and allows noisy historical data to be used for training. Second, the LightGBM model is extended with an incremental learning scheme to make forecasting in real-time possible. Third, a new multi-stream learning strategy that merges data streams with similar concept drift patterns is pioneered to increase the amount of suitable training data while reducing generalization errors. A comprehensive suite of practical tests on real-world datasets demonstrates the merit of these solutions.

Weather forecasting is usually solved through numerical weather prediction (NWP), which can sometimes lead to unsatisfactory performance due to inappropriate setting of the initial states. In this paper, we design a data-driven method augmented by an effective information fusion mechanism to learn from historical data that incorporates prior knowledge from NWP. We cast the weather forecasting problem as an end-to-end deep learning problem and solve it by proposing a novel negative log-likelihood error (NLE) loss function. A notable advantage of our proposed method is that it simultaneously implements single-value forecasting and uncertainty quantification, which we refer to as deep uncertainty quantification (DUQ). Efficient deep ensemble strategies are also explored to further improve performance. This new approach was evaluated on a public dataset collected from weather stations in Beijing, China. Experimental results demonstrate that the proposed NLE loss significantly improves generalization compared to mean squared error (MSE) loss and mean absolute error (MAE) loss. Compared with NWP, this approach significantly improves accuracy by 47.76%, which is a state-of-the-art result on this benchmark dataset.

Aspect term extraction is one of the important subtasks in aspect-based sentiment analysis. Previous studies have shown that using dependency tree structure representation is promising for this task. However, most dependency tree structures involve only one directional propagation on the dependency tree. In this paper, we first propose a novel bidirectional dependency tree network to extract dependency structure features from the given sentences. The key idea is to explicitly incorporate both representations gained separately from the bottom-up and top-down propagation on the given dependency syntactic tree. An end-to-end framework is then developed to integrate the embedded representations and BiLSTM plus CRF to learn both tree-structured and sequential features to solve the aspect term extraction problem. Experimental results demonstrate that the proposed model outperforms state-of-the-art baseline models on four benchmark SemEval datasets.

In many practical engineering applications, the number of actions that have been finished should be known, particularly for an untrimmed video sequence that includes an event with a series of actions, it is important to know the number of actions that have been finished. In this paper, we termed this process as visual event progress estimation (EPE). However, the research related to this problem is few in the research community. To solve this problem, a visual human action analysis-based framework, namely one-shot simultaneously action detection and identification (SADI)-EPE, is presented in this paper. The visual EPE is modeled as an online one-shot learning-based problem; sliding window and attention-based bag of key poses formulate our framework. Unlike most of the action analysis methods relying on a number of training data of some predefined classes, our method can realize SADI for any event if one sample of the event is given, which makes it feasible for practical applications. At the same time, not only SADI but also the progress estimation of the event can be realized by our algorithm. In terms of methodology, the key pose is defined by an invariant pose descriptor from skeletal data and silhouette data. Moreover, in order to extract representative and discriminative poses from one training sample, we present a new bidirectional kNN-based attention weighted key pose selection method, which can filter the unrelated actions and model different importance of various key poses. In addition, an attention-based multi-modal fusion scheme, which addresses the difficulty of high-dimensional features and few training samples, is proposed to augment the performance of our algorithm. Finally, we propose an evaluation criterion for the estimation problem. Extensive results demonstrated the efficacy of our proposed framework.

The residual network has witnessed a great success in computer vision particularly on classification tasks, however, it has not been well studied in regression. In this work, we show its competence in a regression task - crowds flow prediction, which has strong implication to city safety and management. The problem of crowds flow prediction is challenging due to its fast dynamics. To address this issue, we explore residual learning with Gaussian regularization and propose a novel convolutional neural network called Gaussian noise residual networks (Noise-ResNet). Compared with the benchmark ST-ResNet on crowds flow prediction, the proposed architecture has three advantages: 1) Superior performance. Especially, it attains the state-of-the-art results on benchmark dataset BikeNYC. 2) Light architecture. Noise-ResNet only utilises one residual unit rather than STResNet with multiple ones, which greatly reduces the training time. 3) Interpretable input sequences. Noise-ResNet takes an input sequence that only considers the most important periodic data and closeness data, which makes the learning process more interpretable. Furthermore, experimental results substantiate that the Noise-ResNet can outperform ResNet with dropout on the same regression task.