White blood cell (WBC) subtype classification is a critical step in monitoring an individual’s health. However, it remains a challenging task due to the significant morphological variability of WBCs and the domain shift introduced by differing acquisition protocols across hospitals. Numerous approaches have been proposed to mitigate domain shift, including supervised and unsupervised domain adaptation, as well as domain generalisation. These methods, however, require a suitable amount of representative target images, even if unlabelled, or a suitable amount of images from multiple sources, which may not be feasible due to privacy regulations. In this study, we explore an alternative paradigm, known as Distributed Collaborative Machine Learning (DCML), which consists of exploiting images from different sources in a privacy-preserving setup. Although DCML methods seem well suited to this application, to the best of our knowledge, they have not been used for this task or to address the above-mentioned issues. However, we argue that DCML deserves further consideration in medical images as a potential alternative solution against domain shift in a privacy-preserving setup. To substantiate our view, we consider three DCML methods: early and late fusion and federated learning approaches, each offering distinct trade-offs in terms of training constraints, computational overhead and communications costs. We then conduct an extensive, cross-dataset experimental evaluation on four benchmark datasets and provide evidence that even simple implementations of DCML methods can effectively mitigate domain shift in WBC classification tasks.

This study addresses the critical challenge of cell nuclei segmentation in histopathological image analysis, which is essential for cancer diagnosis and prognosis. Traditional segmentation methods often struggle with complexities such as overlapping nuclei and variations in shape and size. Recent advancements in machine learning and deep learning, particularly convolutional neural networks, have improved segmentation accuracy but face limitations due to the need for large annotated datasets, often constrained by privacy regulations in the medical field. This research explores federated learning as a solution, enabling collaborative model training across institutions without sharing sensitive patient data. By leveraging diverse datasets while maintaining privacy, federated learning enhances model robustness and generalization capabilities. The study evaluates various federated learning techniques on in- and out-of-domain test sets, aiming to improve the reliability of segmentation models in clinical settings. The findings suggest that federated learning techniques can effectively address the challenges of data scarcity and domain shift, paving the way for more accurate and widely applicable segmentation algorithms in computational pathology.

Abstract In recent years, there has been a growing interest in synthetic data for several computer vision applications, such as automotive, detection and tracking, surveillance, medical image analysis and robotics. Early use of synthetic data was aimed at performing controlled experiments under the analysis by synthesis approach. Currently, synthetic data are mainly used for training computer vision models, especially deep learning ones, to address well-known issues of real data, such as manual annotation effort, data imbalance and bias, and privacy-related restrictions. In this work, we survey the use of synthetic training data focusing on applications related to video surveillance, whose relevance has rapidly increased in the past few years due to their connection to security: crowd counting, object and pedestrian detection and tracking, behaviour analysis, person re-identification and face recognition. Synthetic training data are even more interesting in this kind of application, to address further, specific issues arising, e.g., from typically unconstrained image or video acquisition conditions and cross-scene application scenarios. We categorise and discuss the existing methods for creating synthetic data, analyse the synthetic data sets proposed in the literature for each of the considered applications, and provide an overview of their effectiveness as training data. We finally discuss whether and to what extent the existing synthetic data sets mitigate the issues of real data, highlight existing open issues, and suggest future research directions in this field.

Person re-identification is a challenging cross-camera matching problem, which is inherently subject to domain shift. To mitigate it, many solutions have been proposed so far, based on four kinds of approaches: supervised and unsupervised domain adaptation, direct transfer, and domain generalisation; in particular, the first two approaches require target data during system design, respectively labelled and unlabelled. In this work, we consider a very different approach, known as human-in-the-loopHITL), which consists of exploiting user’s feedback on target data processed during system operation to improve re-identification accuracy. Although it seems particularly suited to this application, given the inherent interaction with a human operator, HITL methods have been proposed for person re-identification by only a few works so far, and with a different purpose than addressing domain shift. However, we argue that HITL deserves further consideration in person re-identification, also as a potential alternative solution against domain shift. To substantiate our view, we consider simple HITL implementations which do not require model re-training or fine-tuning: they are based on well-known relevance feedback algorithms for content-based image retrieval, and of novel versions of them we devise specifically for person re-identification. We then conduct an extensive, cross-data set experimental evaluation of our HITL implementations on benchmark data sets, and compare them with a large set of existing methods against domain shift, belonging to the four categories mentioned above. Our results provide evidence that HITL can be as effective as, or even outperform, existing ad hoc solutions against domain shift for person re-identification, even under the simple implementations we consider. We believe that these results can foster further research on HITL in the person re-identification field, where, in our opinion, its potential has not been thoroughly explored so far.

Person re-identification is a prominent topic in computer vision due to its security-related applications, and to the fact that issues such as variations in illumination, background, pedestrian pose and clothing appearance make it a very challenging task in real-world scenarios. State-of-the-art supervised methods require a huge manual annotation effort for training data and exhibit limited generalisation capability to unknown target domains. Synthetic data sets have recently been proposed as one possible solution to mitigate these problems, aimed at improving generalisation capability by encompassing a larger amount of variations in the above mentioned visual factors, with no need for manual annotation. However, existing synthetic data sets differ in many aspects, including the number of images, identities and cameras, and in their degree of photorealism, and there is not yet a clear understanding of how all such factors affect person re-identification performance. This work makes a first step towards filling this gap through an indepth empirical investigation, where we use existing synthetic data sets for model training and real benchmark ones for performance evaluation. Our results provide interesting insights towards developing effective synthetic data sets for person re-identification.

Supervised deep learning methods have recently achieved remarkable performance in person re-identification. Unsupervised domain adaptation (UDA) approaches have also been proposed for application scenarios where only unlabelled data are available from target camera views. We consider a more challenging scenario when even collecting a suitable amount of representative, unlabelled target data for offline training or fine-tuning is infeasible. In this context we revisit the human-in-the-loop (HITL) approach, which exploits online the operator's feedback on a small amount of target data. We argue that HITL is a kind of online domain adaptation specifically suited to person re-identification. We then reconsider relevance feedback methods for content-based image retrieval that are computationally much cheaper than state-of-the-art HITL methods for person reidentification, and devise a specific feedback protocol for them. Experimental results show that HITL can achieve comparable or better performance than UDA, and is therefore a valid alternative when the lack of unlabelled target data makes UDA infeasible.

Abstract Given the great success of Convolutional Neural Network (CNN) for image representation and classification tasks, we argue that Content-Based Image Retrieval (CBIR) systems could also leverage on CNN capabilities, mainly when Relevance Feedback (RF) mechanisms are employed. On the one hand, to improve the performances of CBIRs, that are strictly related to the effectiveness of the descriptors used to represent an image, as they aim at providing the user with images similar to an initial query image. On the other hand, to reduce the semantic gap between the similarity perceived by the user and the similarity computed by the machine, by exploiting an RF mechanism where the user labels the returned images as being relevant or not concerning her interests. Consequently, in this work, we propose a CBIR system based on transfer learning from a CNN trained on a vast image database, thus exploiting the generic image representation that it has already learned. Then, the pre-trained CNN is also fine-tuned exploiting the RF supplied by the user to reduce the semantic gap. In particular, after the user’s feedback, we propose to tune and then re-train the CNN according to the labelled set of relevant and non-relevant images. Then, we suggest different strategies to exploit the updated CNN for returning a novel set of images that are expected to be relevant to the user’s needs. Experimental results on different data sets show the effectiveness of the proposed mechanisms in improving the representation power of the CNN with respect to the user concept of image similarity. Moreover, the pros and cons of the different approaches can be clearly pointed out, thus providing clear guidelines for the implementation in production environments.