Ruichu Cai, Junhao Lu, Zhongjie Chen, Boyan Xu, Zhifeng Hao. Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (Volume 1: Long Papers). 2025.

Containers have become the de facto choice for major cloud services. Meanwhile, with demands for extremely high performance, data centers have widely adopted RDMA for their online services. RDMA virtualization is the critical technology that enables RDMA for containers. Hybrid RDMA virtualization leverages the software flexibility in the control path, and keeps the native performance in the data path. Thus, it is the best choice for RDMA virtualization. State-of-the-art hybrid RDMA virtualization cannot address containerspecific problems. This paper proposes DockRDMA, the first hybrid RDMA virtualization solution for containerized clouds. DockRDMA develops several mechanisms, including embedding physical addresses in virtual ones to provide efficient address translation, hybrid network policy enforcement at scale, a general virtual RDMA NIC initialization method to be compatible with all container platforms, and namespace checking to protect the RDMA NIC instances. Evaluation results show that DockRDMA provides bare-metal RDMA performance in the data path, and almost native communication setup time in the control path. Compared with the state-of-the-art hybrid virtualization technology, DockRDMA reduces Hadoop job completion time by 6%. It offers seamless integration with existing container platforms, protects critical information of RDMA NIC instances, and exhibits excellent scalability to meet diverse network policies required by different containers.

Object detection for aerial images has achieved remarkable progress in recent years. Nevertheless, most exiting studies do not differentiate oriented object detection from horizontal detection. Certain schemes ignore the ambiguity of oriented object representation and leverage label assignment designed for horizontal object detection directly. Consequently, it leads to unstable training and causes performance degradation, because high-quality samples surrounding the oriented bounding boxes can not be leveraged effectively. To address this problem, we propose a gliding Free, orientation Free, and anchor Free Network (Free$\rm ^{3}$Net) with high-efficiency for oriented object detection. Specifically, we propose an unambiguous oriented object representation scheme, named FreeGliding, by gliding the projection points of samples on each edge of horizontal bounding boxes. It makes the detection largely free from representation ambiguity and multi-task dependency. To overcome the restrictions of label assignment, we put forward a novel Loss-aware Outer Sample Selection (LOSS) scheme, which takes into consideration spatial information and localization capability to retain high-quality samples surrounding the objects. Moreover, we introduce an Oriented Feature Fusion (OFF) scheme to tackle feature alignment by adjusting the receptive field and fusing oriented features dynamically. Experimental results on two large-scale remote sensing datasets HRSC2016 and DOTA demonstrate that Free$\rm ^{3}$Net outperforms the state-of-the-art schemes with a large margin. We hope our work can inspire rethinking the design of anchor-free detectors, and serve as a strong baseline for oriented object detection.

UNLABELLED: Allosteric ligands have increasingly gained attention as potential therapeutic agents due to their higher target selectivity and lower toxicity compared with classic orthosteric ligands. Despite the great interest in the development of allosteric drugs as a new tactic in drug discovery, the understanding of the ligand-protein interactions underlying allosteric binding represents a key challenge. Herein, we introduce Alloscore, a web server that predicts the binding affinities of allosteric ligand-protein interactions. This method exhibits prominent performance in describing allosteric binding and could be useful in allosteric virtual screening and the structural optimization of allosteric agonists/antagonists. AVAILABILITY AND IMPLEMENTATION: The Alloscore server and tutorials are freely available at http://mdl.shsmu.edu.cn/alloscore CONTACT: [email protected] SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

MOTIVATION: The use of allosteric modulators as preferred therapeutic agents against classic orthosteric ligands has colossal advantages, including higher specificity, fewer side effects and lower toxicity. Therefore, the computational prediction of allosteric sites in proteins is receiving increased attention in the field of drug discovery. Allosite is a newly developed automatic tool for the prediction of allosteric sites in proteins of interest and is now available through a web server. AVAILABILITY: The Allosite server and tutorials are freely available at http://mdl.shsmu.edu.cn/AST CONTACT: [email protected] SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.