Event Stream Super-Resolution (ESR) aims to address the challenge of insufficient spatial resolution in event streams, which holds great significance for the application of event cameras in complex scenarios. Previous works for ESR often process positive and negative events in a mixed paradigm. This paradigm limits their ability to effectively model the unique characteristics of each event and mutually refine each other by considering their correlations. In this paper, we propose a bilateral event mining and complementary network (BMCNet) to fully leverage the potential of each event and capture the shared information to complement each other simultaneously. Specifically, we resort to a two-stream network to accomplish comprehensive mining of each type of events individually. To facilitate the exchange of information between two streams, we propose a bilateral information exchange (BIE) module. This module is layer-wisely embedded between two streams, enabling the effective propagation of hierarchical global information while alleviating the impact of invalid information brought by inherent characteristics of events. The experimental results demonstrate that our approach outperforms the previous state-of-the-art methods in ESR, achieving performance improvements of over 11% on both real and synthetic datasets. Moreover, our method significantly enhances the performance of event-based downstream tasks such as object recognition and video reconstruction. Our code is available at https://github.com/Lqm26/BMCNet-ESR.

Generating ligand molecules that bind to specific protein targets via generative models holds substantial promise for advancing structure-based drug design. Existing methods generate molecules from scratch without reference or template ligands, which poses challenges in model optimization and may yield suboptimal outcomes. To address this problem, we propose an innovative interaction-based retrieval-augmented diffusion model named IRDiff to facilitate target-aware molecule generation. IRDiff leverages a curated set of ligand references, i.e., those with desired properties such as high binding affinity, to steer the diffusion model towards synthesizing ligands that satisfy design criteria. Specifically, we utilize a protein-molecule interaction network (PMINet), which is pretrained with binding affinity signals to: (i) retrieve target-aware ligand molecules with high binding affinity to serve as references, and (ii) incorporate essential protein-ligand binding structures for steering molecular diffusion generation with two effective augmentation mechanisms, i.e., retrieval augmentation and self augmentation. Empirical studies on CrossDocked2020 dataset show IRDiff can generate molecules with more realistic 3D structures and achieve state-of-the-art binding affinities towards the protein targets, while maintaining proper molecular properties. The codes and models are available at https://github.com/YangLing0818/IRDiff

With the advancement of AIGC, video frame interpolation (VFI) has become a crucial component in existing video generation frameworks, attracting widespread research interest. For the VFI task, the motion estimation between neighboring frames plays a crucial role in avoiding motion ambiguity. However, existing VFI methods always struggle to accurately predict the motion information between consecutive frames, and this imprecise estimation leads to blurred and visually incoherent interpolated frames. In this paper, we propose a novel diffusion framework, Motion-Aware latent Diffusion models (MADiff), which is specifically designed for the VFI task. By incorporating motion priors between the conditional neighboring frames with the target interpolated frame predicted throughout the diffusion sampling procedure, MADiff progressively refines the intermediate outcomes, culminating in generating both visually smooth and realistic results. Extensive experiments conducted on benchmark datasets demonstrate that our method achieves state-of-the-art performance significantly outperforming existing approaches, especially under challenging scenarios involving dynamic textures with complex motion.