Fraudulent activities on blockchain networks threaten the integrity and reliability of decentralized finance ecosystems. Accurately identifying malicious nodes such as phishing or ransomware addresses, within large-scale blockchain transaction graphs remains a critical challenge due to their dynamic, sparse, and continuously evolving topologies. Transfer learning offers a powerful paradigm for fraud detection because many fraudulent schemes, including ransomware and phishing, are often orchestrated by overlapping actor groups that share behavioral and structural patterns across networks. Leveraging these shared representations enables knowledge transfer from previously observed fraud types to emerging ones. However, the complex and multi-modal nature of digital financial systems introduces substantial challenges for graph-based transfer learning. Fraudulent activities are shaped by diverse modalities including graph structure, transaction sequences, temporal price dynamics, and textual metadata, while distributional shifts frequently occur across time and platforms. Existing graph transfer learning methods struggle to model such multi-modal dependencies and to align divergent feature distributions. To tackle these challenges, we develop a Multi-mOdal Enhanced Graph Transfer Learning (MOE-GTL) framework which incorporates graph, temporal, and textual modalities for fraudulent node detection. We further introduce Temporal-aware Maximum Mean Discrepancy (TMMD), a regularization mechanism that explicitly aligns multi-modal feature distributions between source and target graphs over time. Extensive experiments reveal that our MOE-GTL model notably improves the accuracy of fraudulent node classifications on Ethereum and Solana transaction graphs.

The variational autoencoder-based method has been widely used for modeling massive datasets. However, for 3D images, simultaneously achieving disentangled representations, low-variance Evidence Lower Bounds (ELBO), and a lightweight model remains a challenging task. In this work, we propose a Langevin dynamics-based inference framework that integrates target data information for efficient likelihood inference and disentangles appearance and morphology features via multi-scale energy-level encoding that enables unsupervised disentanglement. We adopt a quasi-symplectic integrator to handle the Hessian-related computational bottleneck that often arises in Langevin-based flow inference. We demonstrate both theoretical and empirical effectiveness of our approach compared to other methods. Experiments on public benchmarks and clinical 3D imaging datasets show that our Langevin-VAE achieves high-quality generation and learns disentangled shape and appearance representations with a model size of only 1.7M parameters. The code will be available at: https://github.com/LaplaceCenter/LangevinVAE.

Cross-modality data translation has attracted great interest in medical image computing. Deep generative models show performance improvement in addressing related challenges. Nevertheless, as a fundamental challenge in image translation, the problem of zero-shot learning cross-modality image translation with fidelity remains unanswered. To bridge this gap, we propose a novel unsupervised zero-shot learning method called Mutual Information guided Diffusion Model, which learns to translate an unseen source image to the target modality by leveraging the inherent statistical consistency of Mutual Information between different modalities. To overcome the prohibitive high dimensional Mutual Information calculation, we propose a differentiable local-wise mutual information layer for conditioning the iterative denoising process. The Local-wise-Mutual-Information-Layer captures identical cross-modality features in the statistical domain, offering diffusion guidance without relying on direct mappings between the source and target domains. This advantage allows our method to adapt to changing source domains without the need for retraining, making it highly practical when sufficient labeled source domain data is not available. We demonstrate the superior performance of MIDiffusion in zero-shot cross-modality translation tasks through empirical comparisons with other generative models, including adversarial-based and diffusion-based models. Finally, we showcase the real-world application of MIDiffusion in 3D zero-shot learning-based cross-modality image segmentation tasks.