Monique Meuschke

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40ranked-venue papers
11as first author
28since 2021 · last 2026
0000-0001-9098-504XORCID · conflict

Domains — the database's venue-derived domains; a paper can count in several

Graphics, computer vision, multimedia, augmented reality and games · 37 · 11 first-author · 25 since 2021Artificial intelligence and machine learning · 2 · 2 since 2021Human-computer interaction and ubiquitous computing · 2 · 2 since 2021Applied, interdisciplinary, general and emerging computing · 2 · 2 since 2021
YearPublicationVenuePosition
2026 Foreword to special section on 15th Eurographics workshop on visual computing for biology and medicine
Alessio Arleo, Jan Byska, Monique Meuschke
Comput. Graph.3
2026 VocalVis: Bridging voice-based control and 3D surface visualization
abstract
Exploring 3D surface data often involves navigating complex menus, creating challenges for both experts and new users who may struggle with overloaded interfaces. To address this, we introduce VocalVis , an open-source prototype that leverages real-time voice processing to simplify interaction and analysis of 3D surface data. By capitalizing on advancements in natural language processing, VocalVis enables users to interact with digital content through voice commands, addressing challenges associated with traditional navigation methods. Our study involves both data scientist novices and domain experts, offering insights into how voice interaction can streamline data exploration. The findings demonstrate the potential of voice as a powerful supplementary tool for visually analyzing complex datasets. This innovative approach opens up new possibilities for intuitive, accessible data exploration, making it convenient for a broader range of users to engage with 3D scientific data.
Jan N. Hombeck, Henrik Voigt, Jasna Nuhic, Monique Meuschke, Kai Lawonn
Comput. Graph.4
2026 Corrections to "Perceptually Uniform Construction of Illustrative Textures"
abstract
This note corrects errors in Figs. 12 and 13 and the description of the parametric function in the paper "Perceptually Uniform Construction of Illustrative Textures" published in IEEE Transactions on Visualization and Computer Graphics, Vol. 30, Issue 1, 2024.
Anna Sterzik, Monique Meuschke, Douglas W. Cunningham, Kai Lawonn
IEEE Trans. Vis. Comput. Graph.2
2025 Either Or: Interactive Articles or Videos for Climate Science Communication
abstract
Abstract Effective communication of climate science is critical as climate‐related disasters become more frequent and severe. Translating complex information, such as uncertainties in climate model predictions, into formats accessible to diverse audiences is key to informed decision‐making and public engagement. This study investigates how different teaching formats can enhance understanding of these uncertainties. This study compares two multimodal strategies: (1) a text‐image format with interactive components and (2) an explainer video combining dynamic visuals with narration. Participants' immediate and delayed retention (one week) and engagement are assessed to determine which format offers greater saliency. Sample analysis (n = 622) displayed equivalent retention by viewers between both formats. Metrics assessing interactivity found no correlation between interactivity and information retention. However, a stark contrast was observed in the time viewers spent engaging with each format. The video format was 29% more efficient with information taught over a period of time vs. the article. Additionally, retention on the video format worsened with age (P = 0.004) while retention on the article format improved with education (P = 0.038). These results align with previous findings in literature.
Jeran Poehls, Monique Meuschke, Nuno Carvalhais, Kai Lawonn
Comput. Graph. Forum2
2025 A survey of intracranial aneurysm detection and segmentation
abstract
Intracranial aneurysms (IAs) are a critical public health concern: they are asymptomatic and can lead to fatal subarachnoid hemorrhage in case of rupture. Neuroradiologists rely on advanced imaging techniques to identify aneurysms in a patient and consider the characteristics of IAs along with several other patient-related factors for rupture risk assessment and treatment decision-making. The process of diagnostic image reading is time-intensive and prone to inter- and intra-individual variations, so researchers have proposed many computer-aided diagnosis (CAD) systems for aneurysm detection and segmentation. This paper provides a comprehensive literature survey of semi-automated and automated approaches for IA detection and segmentation and proposes a taxonomy to classify the approaches. We also discuss the current issues and give some insight into the future direction of CAD systems for IA detection and segmentation.
Wei-Chan Hsu, Monique Meuschke, Alejandro F. Frangi, Bernhard Preim, Kai Lawonn
Medical Image Anal.2
2024 Expert exploranation for communicating scientific methods - A case study in conflict research
abstract
Science communication aims at making key research insights accessible to the broad public. If explanatory and exploratory visualization techniques are combined to do so, the approach is also referred to as exploranation. In this context, the audience is usually not required to have domain expertise. However, we show that exploranation can not only support the communication between researchers and a broad audience, but also between researchers directly. With the goal of communicating an existing method for conducting causal inference on spatio-temporal conflict event data, we investigated how to perform exploranation for experts, i.e., expert exploranation. Based on application scenarios of the inference method, we developed three versions of an interactive visual story to explain the method to conflict researchers. We abstracted the corresponding design process and evaluated the stories both with experts who were unfamiliar with the explained method and experts who were already familiar with it. The positive and extensive feedback from the evaluation shows that expert exploranation is a promising direction for visual storytelling, as it can help to improve scientific outreach, methodological understanding, and accessibility for researchers new to a field.
Benedikt Mayer, Karsten Donnay, Kai Lawonn, Bernhard Preim, Monique Meuschke
Comput. Graph.5
2024 Visually communicating pathological changes: A case study on the effectiveness of phong versus outline shading
abstract
In this paper, we investigate the suitability of different visual representations of pathological growth and shrinkage using surface models of intracranial aneurysms and liver tumors. By presenting complex medical information in a visually accessible manner, audiences can better understand and comprehend the progression of pathological structures. Previous work in medical visualization provides an extensive design space for visualizing medical image data. However, determining which visualization techniques are appropriate for a general audience has not been thoroughly investigated. We conducted a user study (n = 40) to evaluate different visual representations in terms of their suitability for solving tasks and their aesthetics. We created surface models representing the evolution of pathological structures over multiple discrete time steps and visualized them using illumination-based and illustrative techniques. Our results indicate that users’ aesthetic preferences largely coincide with their preferred visualization technique for task-solving purposes. In general, the illumination-based technique has been preferred to the illustrative technique, but the latter offers great potential for increasing the accessibility of visualizations to users with color vision deficiencies.
Sarah Mittenentzwei, Sophie Mlitzke, Darija Grisanova, Kai Lawonn, Bernhard Preim, Monique Meuschke
Comput. Graph.6
2024 InverseVis: Revealing the Hidden with Curved Sphere Tracing
abstract
Abstract Exploratory analysis of scalar fields on surface meshes presents significant challenges in identifying and visualizing important regions, particularly on the surface's backside. Previous visualization methods achieved only a limited visibility of significant features, i.e., regions with high or low scalar values, during interactive exploration. In response to this, we propose a novel technique, InverseVis, which leverages curved sphere tracing and uses the otherwise unused space to enhance visibility. Our approach combines direct and indirect rendering, allowing camera rays to wrap around the surface and reveal information from the backside. To achieve this, we formulate an energy term that guides the image synthesis in previously unused space, highlighting the most important regions of the backside. By quantifying the amount of visible important features, we optimize the camera position to maximize the visibility of the scalar field on both the front and backsides. InverseVis is benchmarked against state‐of‐the‐art methods and a derived technique, showcasing its effectiveness in revealing essential features and outperforming existing approaches.
Kai Lawonn, Monique Meuschke, Tobias Günther
Comput. Graph. Forum2
2024 A Survey of Medical Visualization Through the Lens of Metaphors
abstract
We provide an overview of metaphors that were used in medical visualization and related user interfaces. Metaphors are employed to translate concepts from a source domain to a target domain. The survey is grounded in a discussion of metaphor-based design involving the identification and reflection of candidate metaphors. We consider metaphors that have a source domain in one branch of medicine, e.g., the virtual mirror that solves problems in orthopedics and laparoscopy with a mirror that resembles the dentist's mirror. Other metaphors employ the physical world as the source domain, such as crepuscular rays that inspire a solution for access planning in tumor therapy. Aviation is another source of inspiration, leading to metaphors, such as surgical cockpits, surgical control towers, and surgery navigation according to an instrument flight. This paper should raise awareness for metaphors and their potential to focus the design of computer-assisted systems on useful features and a positive user experience. Limitations and potential drawbacks of a metaphor-based user interface design for medical applications are also considered.
Bernhard Preim, Monique Meuschke, Veronika Weiß
IEEE Trans. Vis. Comput. Graph.2
2024 Perceptually Uniform Construction of Illustrative Textures
abstract
Illustrative textures, such as stippling or hatching, were predominantly used as an alternative to conventional Phong rendering. Recently, the potential of encoding information on surfaces or maps using different densities has also been recognized. This has the significant advantage that additional color can be used as another visual channel and the illustrative textures can then be overlaid. Effectively, it is thus possible to display multiple information, such as two different scalar fields on surfaces simultaneously. In previous work, these textures were manually generated and the choice of density was unempirically determined. Here, we first want to determine and understand the perceptual space of illustrative textures. We chose a succession of simplices with increasing dimensions as primitives for our textures: Dots, lines, and triangles. Thus, we explore the texture types of stippling, hatching, and triangles. We create a range of textures by sampling the density space uniformly. Then, we conduct three perceptual studies in which the participants performed pairwise comparisons for each texture type. We use multidimensional scaling (MDS) to analyze the perceptual spaces per category. The perception of stippling and triangles seems relatively similar. Both are adequately described by a 1D manifold in 2D space. The perceptual space of hatching consists of two main clusters: Crosshatched textures, and textures with only one hatching direction. However, the perception of hatching textures with only one hatching direction is similar to the perception of stippling and triangles. Based on our findings, we construct perceptually uniform illustrative textures. Afterwards, we provide concrete application examples for the constructed textures.
Anna Sterzik, Monique Meuschke, Douglas W. Cunningham, Kai Lawonn
IEEE Trans. Vis. Comput. Graph.2
2023 Investigating user behavior in slideshows and scrollytelling as narrative genres in medical visualization
Sarah Mittenentzwei, Laura A. Garrison, Eric Mörth, Kai Lawonn, Stefan Bruckner, Bernhard Preim, Monique Meuschke
Comput. Graph.7
2023 A Characterization of Interactive Visual Data Stories With a Spatio-Temporal Context
abstract
Abstract Large‐scale issues with a spatial and temporal context such as the COVID‐19 pandemic, the war against Ukraine, and climate change have given visual storytelling with data a lot of attention in online journalism, confirming its high effectiveness and relevance for conveying stories. Thus, new ways have emerged that expand the space of visual storytelling techniques. However, interactive visual data stories with a spatio‐temporal context have not been extensively studied yet. Particularly quantitative information about the used layout and media, the visual storytelling techniques, and the visual encoding of space‐time is relevant to get a deeper understanding of how such stories are commonly built to convey complex information in a comprehensible way. Covering these three aspects, we propose a design space derived by merging and adjusting existing approaches, which we used to categorize 130 collected web‐based visual data stories with a spatio‐temporal context from between 2018 and 2022. An analyzis of the collected data reveals the power of large‐scale issues to shape the landscape of storytelling techniques and a trend towards a simplified consumability of stories. Taken together, our findings can serve story authors as inspiration regarding which storytelling techniques to include in their own spatio‐temporal data stories.
Benedikt Mayer, Nastasja Steinhauer, Bernhard Preim, Monique Meuschke
Comput. Graph. Forum4
2023 Do Disease Stories Need a Hero? Effects of Human Protagonists on a Narrative Visualization about Cerebral Small Vessel Disease
abstract
Abstract Authors use various media formats to convey disease information to a broad audience, from articles and videos to interviews or documentaries. These media often include human characters, such as patients or treating physicians, who are involved with the disease. While artistic media, such as hand‐crafted illustrations and animations are used for health communication in many cases, our goal is to focus on data‐driven visualizations. Over the last decade, narrative visualization has experienced increasing prominence, employing storytelling techniques to present data in an understandable way. Similar to classic storytelling formats, narrative medical visualizations may also take a human character‐centered design approach. However, the impact of this form of data communication on the user is largely unexplored. This study investigates the protagonist's influence on user experience in terms of engagement, identification, self‐referencing, emotional response, perceived credibility, and time spent in the story. Our experimental setup utilizes a character‐driven story structure for disease stories derived from Joseph Campbell's Hero's Journey. Using this structure, we generated three conditions for a cerebral small vessel disease story that vary by their protagonist: (1) a patient, (2) a physician, and (3) a base condition with no human protagonist. These story variants formed the basis for our hypotheses on the effect of a human protagonist in disease stories, which we evaluated in an online study with 30 participants. Our findings indicate that a human protagonist exerts various influences on the story perception and that these also vary depending on the type of protagonist.
Sarah Mittenentzwei, Veronika Weiß, Stefanie Schreiber, Laura A. Garrison, Stefan Bruckner, Malte Pfister, Bernhard Preim, Monique Meuschke
Comput. Graph. Forum8
2023 GRay: Ray Casting for Visualization and Interactive Data Exploration of Gaussian Mixture Models
abstract
The Gaussian mixture model (GMM) describes the distribution of random variables from several different populations. GMMs have widespread applications in probability theory, statistics, machine learning for unsupervised cluster analysis and topic modeling, as well as in deep learning pipelines. So far, few efforts have been made to explore the underlying point distribution in combination with the GMMs, in particular when the data becomes high-dimensional and when the GMMs are composed of many Gaussians. We present an analysis tool comprising various GPU-based visualization techniques to explore such complex GMMs. To facilitate the exploration of high-dimensional data, we provide a novel navigation system to analyze the underlying data. Instead of projecting the data to 2D, we utilize interactive 3D views to better support users in understanding the spatial arrangements of the Gaussian distributions. The interactive system is composed of two parts: (1) raycasting-based views that visualize cluster memberships, spatial arrangements, and support the discovery of new modes. (2) overview visualizations that enable the comparison of Gaussians with each other, as well as small multiples of different choices of basis vectors. Users are supported in their exploration with customization tools and smooth camera navigations. Our tool was developed and assessed by five domain experts, and its usefulness was evaluated with 23 participants. To demonstrate the effectiveness, we identify interesting features in several data sets.
Kai Lawonn, Monique Meuschke, Pepe Eulzer, Matthias Mitterreiter, Joachim Giesen, Tobias Günther
IEEE Trans. Vis. Comput. Graph.2
2023 GUCCI - Guided Cardiac Cohort Investigation of Blood Flow Data
abstract
We present the framework GUCCI (Guided Cardiac Cohort Investigation), which provides a guided visual analytics workflow to analyze cohort-based measured blood flow data in the aorta. In the past, many specialized techniques have been developed for the visual exploration of such data sets for a better understanding of the influence of morphological and hemodynamic conditions on cardiovascular diseases. However, there is a lack of dedicated techniques that allow visual comparison of multiple data sets and defined cohorts, which is essential to characterize pathologies. GUCCI offers visual analytics techniques and novel visualization methods to guide the user through the comparison of predefined cohorts, such as healthy volunteers and patients with a pathologically altered aorta. The combination of overview and glyph-based depictions together with statistical cohort-specific information allows investigating differences and similarities of the time-dependent data. Our framework was evaluated in a qualitative user study with three radiologists specialized in cardiac imaging and two experts in medical blood flow visualization. They were able to discover cohort-specific characteristics, which supports the derivation of standard values as well as the assessment of pathology-related severity and the need for treatment.
Monique Meuschke, Uli Niemann, Benjamin Behrendt, Matthias Gutberlet, Bernhard Preim, Kai Lawonn
IEEE Trans. Vis. Comput. Graph.1
2023 Visual Assistance in Development and Validation of Bayesian Networks for Clinical Decision Support
abstract
The development and validation of Clinical Decision Support Models (CDSM) based on Bayesian networks (BN) is commonly done in a collaborative work between medical researchers providing the domain expertise and computer scientists developing the decision support model. Although modern tools provide facilities for data-driven model generation, domain experts are required to validate the accuracy of the learned model and to provide expert knowledge for fine-tuning it while computer scientists are needed to integrate this knowledge in the learned model (hybrid modeling approach). This generally time-expensive procedure hampers CDSM generation and updating. To address this problem, we developed a novel interactive visual approach allowing medical researchers with less knowledge in CDSM to develop and validate BNs based on domain specific data mainly independently and thus, diminishing the need for an additional computer scientist. In this context, we abstracted and simplified the common workflow in BN development as well as adjusted the workflow to medical experts' needs. We demonstrate our visual approach with data of endometrial cancer patients and evaluated it with six medical researchers who are domain experts in the gynecological field.
Juliane Müller-Sielaff, Seyed Behnam Beladi, Stephanie W. Vrede, Monique Meuschke, Peter J. F. Lucas, Johanna M. A. Pijnenborg, Steffen Oeltze-Jafra
IEEE Trans. Vis. Comput. Graph.4
2022 Classification of cardiac cohorts based on morphological and hemodynamic features derived from 4D PC-MRI data
abstract
An accurate assessment of the cardiovascular system and prediction of cardiovascular diseases (CVDs) are crucial. Cardiac blood flow data provide insights about patient-specific hemodynamics. However, there is a lack of machine learning approaches for a feature-based classification of heart-healthy people and patients with CVDs. In this paper, we investigate the potential of morphological and hemodynamic features extracted from measured blood flow data in the aorta to classify heart-healthy volunteers (HHV) and patients with bicuspid aortic valve (BAV). Furthermore, we determine features that distinguish male vs. female patients and elderly HHV vs. BAV patients. We propose a data analysis pipeline for cardiac status classification, encompassing feature selection, model training, and hyperparameter tuning. Our results suggest substantial differences in flow features of the aorta between HHV and BAV patients. The excellent performance of the classifiers separating between elderly HHV and BAV patients indicates that aging is not associated with pathological morphology and hemodynamics. Our models represent a first step towards automated diagnosis of CVS using interpretable machine learning models.
Uli Niemann, Atrayee Neog, Benjamin Behrendt, Kai Lawonn, Matthias Gutberlet, Myra Spiliopoulou, Bernhard Preim, Monique Meuschke
CBMS8
2022 The Why and The How: A Survey on Natural Language Interaction in Visualization
abstract
Henrik Voigt, Ozge Alacam, Monique Meuschke, Kai Lawonn, Sina Zarrieß. Proceedings of the 2022 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies. 2022.
Henrik Voigt, Özge Alaçam, Monique Meuschke, Kai Lawonn, Sina Zarrieß
NAACL-HLT3
2022 Evaluating Perceptional Tasks for Medicine: A Comparative User Study Between a Virtual Reality and a Desktop Application
abstract
Since for most consumers the Virtual Reality (VR) experience exceeds that of desktop applications, an increasing number of applications is being transferred from desktop to VR. Industrial and entertainment applications primarily expect for a richer consumer experience, while others, such as surgical applications, seek for improved precision over their desktop counterparts. One way to improve the performance of precision-based VR applications is to provide suitable visualizations. Today, these "suitable" visualizations are mostly transferred from desktop to VR without considering their spatial and temporal performance might change in VR. This may not lead to an optimal solution, which can be crucial for precision-based tasks. Misinterpretation of shape or distance in a surgical or pre-operative simulation can affect the chosen treatment and thus directly impact the outcome. Therefore, we evaluate the performance differences of multiple visualizations for 3D surfaces based on their shape and distance estimation for desktop and VR applications. We conducted a quantitative user study with 56 participants evaluating seven visualizations (Phong, Toon, Fresnel, Pseudo-Chromadepth, Heatmap, Isolines, and Arrow Glyphs). Our results show that the performance of each visualization varies depending on the task, system, and surface type, with VR generally providing improved results. While Isolines are able to improve distance estimation, Phong and Heatmaps are beneficial for shape estimation.
Jan N. Hombeck, Monique Meuschke, Lennert Zyla, André-Joel Heuser, Justus Toader, Felix Popp, Christiane J. Bruns, Christian Hansen 0001, Rabi R. Datta, Kai Lawonn
VR2
2022 Narrative medical visualization to communicate disease data
Monique Meuschke, Laura A. Garrison, Noeska N. Smit, Benjamin Bach, Sarah Mittenentzwei, Veronika Weiß, Stefan Bruckner, Kai Lawonn, Bernhard Preim
Comput. Graph.1
2022 Corrigendum to "A Survey of Medical Animations" [Comput. Graph. 90 (2020) 145-168]
Bernhard Preim, Monique Meuschke
Comput. Graph.2
2022 A survey of medical animations
Bernhard Preim, Monique Meuschke
Comput. Graph.2
2022 Vessel Maps: A Survey of Map-Like Visualizations of the Cardiovascular System
abstract
Abstract Map‐like visualizations of patient‐specific cardiovascular structures have been applied in numerous medical application contexts. The term map‐like alludes to the characteristics these depictions share with cartographic maps: they show the spatial relations of data attributes from a single perspective, they abstract the underlying data to inCrease legibility, and they facilitate tasks centered around overview, navigation, and comparison. A vast landscape of techniques exists to derive such maps from heterogeneous data spaces. Yet, they all target similar purposes within disease diagnostics, treatment, or research and they face coinciding challenges in mapping the spatial component of a treelike structure to a legible layout. In this report, we present a framing to unify these approaches. On the one hand, we provide a classification of the existing literature according to the data spaces such maps can be derived from. On the other hand, we view the approaches in light of the manifold requirements medical practitioners and researchers have in their efforts to combat the ever‐growing burden of cardiovascular disease. Based on these two perspectives, we offer recommendations for the design of map‐like visualizations of the cardiovascular system.
Pepe Eulzer, Monique Meuschke, Gabriel Mistelbauer, Kai Lawonn
Comput. Graph. Forum2
2021 Estimating depth information of vascular models: A comparative user study between a virtual reality and a desktop application
Florian Heinrich, Vikram Apilla, Kai Lawonn, Christian Hansen 0001, Bernhard Preim, Monique Meuschke
Comput. Graph.6
2021 Aneulysis - A system for the visual analysis of aneurysm data
Monique Meuschke, Bernhard Preim, Kai Lawonn
Comput. Graph.1
2021 Skyscraper visualization of multiple time-dependent scalar fields on surfaces
Monique Meuschke, Samuel Voß, Franziska Gaidzik, Bernhard Preim, Kai Lawonn
Comput. Graph.1
2021 Visualizing Carotid Blood Flow Simulations for Stroke Prevention
abstract
Abstract In this work, we investigate how concepts from medical flow visualization can be applied to enhance stroke prevention diagnostics. Our focus lies on carotid stenoses, i.e., local narrowings of the major brain‐supplying arteries, which are a frequent cause of stroke. Carotid surgery can reduce the stroke risk associated with stenoses, however, the procedure entails risks itself. Therefore, a thorough assessment of each case is necessary. In routine diagnostics, the morphology and hemodynamics of an afflicted vessel are separately analyzed using angiography and sonography, respectively. Blood flow simulations based on computational fluid dynamics could enable the visual integration of hemodynamic and morphological information and provide a higher resolution on relevant parameters. We identify and abstract the tasks involved in the assessment of stenoses and investigate how clinicians could derive relevant insights from carotid blood flow simulations. We adapt and refine a combination of techniques to facilitate this purpose, integrating spatiotemporal navigation, dimensional reduction, and contextual embedding. We evaluated and discussed our approach with an interdisciplinary group of medical practitioners, fluid simulation and flow visualization researchers. Our initial findings indicate that visualization techniques could promote usage of carotid blood flow simulations in practice.
Pepe Eulzer, Monique Meuschke, Carsten Klingner, Kai Lawonn
Comput. Graph. Forum2
2021 VEHICLE: Validation and Exploration of the Hierarchical Integration of Conflict Event Data
abstract
Abstract The exploration of large‐scale conflicts, as well as their causes and effects, is an important aspect of socio‐political analysis. Since event data related to major conflicts are usually obtained from different sources, researchers developed a semi‐automatic matching algorithm to integrate event data of different origins into one comprehensive dataset using hierarchical taxonomies. The validity of the corresponding integration results is not easy to assess since the results depend on user‐defined input parameters and the relationships between the original data sources. However, only rudimentary visualization techniques have been used so far to analyze the results, allowing no trustworthy validation or exploration of how the final dataset is composed. To overcome this problem, we developedVEHICLE, a web‐based tool to validate and explore the results of the hierarchical integration. For the design, we collaborated with a domain expert to identify the underlying domain problems and derive a task and workflow description. The tool combines both traditional and novel visual analysis techniques, employing statistical and map‐based depictions as well as advanced interaction techniques. We showed the usefulness ofVEHICLEin two case studies and by conducting an evaluation together with conflict researchers, confirming domain hypotheses and generating new insights.
Benedikt Mayer, Kai Lawonn, Karsten Donnay, Bernhard Preim, Monique Meuschke
Comput. Graph. Forum5
2020 A survey of medical animations
Bernhard Preim, Monique Meuschke
Comput. Graph.2
2019 EvalViz - Surface visualization evaluation wizard for depth and shape perception tasks
Monique Meuschke, Noeska N. Smit, Nils Lichtenberg, Bernhard Preim, Kai Lawonn
Comput. Graph.1
2019 A Geometric Optimization Approach for the Detection and Segmentation of Multiple Aneurysms
abstract
Abstract We present a method for detecting and segmenting aneurysms in blood vessels that facilitates the assessment of risks associated with the aneurysms. The detection and analysis of aneurysms is important for medical diagnosis as aneurysms bear the risk of rupture with fatal consequences for the patient. For risk assessment and treatment planning, morphological descriptors, such as the height and width of the aneurysm, are used. Our system enables the fast detection, segmentation and analysis of single and multiple aneurysms. The method proceeds in two stages plus an optional third stage in which the user interacts with the system. First, a set of aneurysm candidate regions is created by segmenting regions of the vessels. Second, the aneurysms are detected by a classification of the candidates. The third stage allows users to adjust and correct the result of the previous stages using a brushing interface. When the segmentation of the aneurysm is complete, the corresponding ostium curves and morphological descriptors are computed and a report including the results of the analysis and renderings of the aneurysms is generated. The novelty of our approach lies in combining an analytic characterization of aneurysms and vessels to generate a list of candidate regions with a classifier trained on data to identify the aneurysms in the candidate list. The candidate generation is modeled as a global combinatorial optimization problem that is based on a local geometric characterization of aneurysms and vessels and can be efficiently solved using a graph cut algorithm. For the aneurysm classification scheme, we identified four suitable features and modeled appropriate training data. An important aspect of our approach is that the resulting system is fast enough to allow for user interaction with the global optimization by specifying additional constraints via a brushing interface.
Kai Lawonn, Monique Meuschke, Ralph Wickenhöfer, Bernhard Preim, Klaus Hildebrandt
Comput. Graph. Forum2
2019 Generation and Visual Exploration of Medical Flow Data: Survey, Research Trends and Future Challenges
abstract
Abstract Simulations and measurements of blood and airflow inside the human circulatory and respiratory system play an increasingly important role in personalized medicine for prevention, diagnosis and treatment of diseases. This survey focuses on three main application areas. (1) Computational fluid dynamics (CFD) simulations of blood flow in cerebral aneurysms assist in predicting the outcome of this pathologic process and of therapeutic interventions. (2) CFD simulations of nasal airflow allow for investigating the effects of obstructions and deformities and provide therapy decision support. (3) 4D phase‐contrast (4D PC) magnetic resonance imaging of aortic haemodynamics supports the diagnosis of various vascular and valve pathologies as well as their treatment. An investigation of the complex and often dynamic simulation and measurement data requires the coupling of sophisticated visualization, interaction and data analysis techniques. In this paper, we survey the large body of work that has been conducted within this realm. We extend previous surveys by incorporating nasal airflow, addressing the joint investigation of blood flow and vessel wall properties and providing a more fine‐granular taxonomy of the existing techniques. From the survey, we extract major research trends and identify open problems and future challenges. The survey is intended for researchers interested in medical flow but also more general, in the combined visualization of physiology and anatomy, the extraction of features from flow field data and feature‐based visualization, the visual comparison of different simulation results and the interactive visual analysis of the flow field and derived characteristics.
Steffen Oeltze-Jafra, Monique Meuschke, Mathias Neugebauer, Sylvia Saalfeld, Kai Lawonn, Gábor Janiga, Hans-Christian Hege, Stefan Zachow, Bernhard Preim
Comput. Graph. Forum2
2019 Visual Analysis of Aneurysm Data using Statistical Graphics
abstract
This paper presents a framework to explore multi-field data of aneurysms occurring at intracranial and cardiac arteries by using statistical graphics. The rupture of an aneurysm is often a fatal scenario, whereas during treatment serious complications for the patient can occur. Whether an aneurysm ruptures or whether a treatment is successful depends on the interaction of different morphological such as wall deformation and thickness, and hemodynamic attributes like wall shear stress and pressure. Therefore, medical researchers are very interested in better understanding these relationships. However, the required analysis is a time-consuming process, where suspicious wall regions are difficult to detect due to the time-dependent behavior of the data. Our proposed visualization framework enables medical researchers to efficiently assess aneurysm risk and treatment options. This comprises a powerful set of views including 2D and 3D depictions of the aneurysm morphology as well as statistical plots of different scalar fields. Brushing and linking aids the user to identify interesting wall regions and to understand the influence of different attributes on the aneurysm's state. Moreover, a visual comparison of pre- and post-treatment as well as different treatment options is provided. Our analysis techniques are designed in collaboration with domain experts, e.g., physicians, and we provide details about the evaluation.
Monique Meuschke, Tobias Günther, Philipp Berg, Ralph Wickenhöfer, Bernhard Preim, Kai Lawonn
IEEE Trans. Vis. Comput. Graph.1
2019 Classification of Blood Flow Patterns in Cerebral Aneurysms
abstract
We present a Cerebral Aneurysm Vortex Classification (CAVOCLA) that allows to classify blood flow in cerebral aneurysms. Medical studies assume a strong relation between the progression and rupture of aneurysms and flow patterns. To understand how flow patterns impact the vessel morphology, they are manually classified according to predefined classes. However, manual classifications are time-consuming and exhibit a high inter-observer variability. In contrast, our approach is more objective and faster than manual methods. The classification of integral lines, representing steady or unsteady blood flow, is based on a mapping of the aneurysm surface to a hemisphere by calculating polar-based coordinates. The lines are clustered and for each cluster a representative is calculated. Then, the polar-based coordinates are transformed to the representative as basis for the classification. Classes are based on the flow complexity. The classification results are presented by a detail-on-demand approach using a visual transition from the representative over an enclosing surface to the associated lines. Based on seven representative datasets, we conduct an informal interview with five domain experts to evaluate the system. They confirmed that CAVOCLA allows for a robust classification of intra-aneurysmal flow patterns. The detail-on-demand visualization enables an efficient exploration and interpretation of flow patterns.
Monique Meuschke, Steffen Oeltze-Jafra, Oliver Beuing, Bernhard Preim, Kai Lawonn
IEEE Trans. Vis. Comput. Graph.1
2018 Exploration of blood flow patterns in cerebral aneurysms during the cardiac cycle
Monique Meuschke, Samuel Voß, Bernhard Preim, Kai Lawonn
Comput. Graph.1
2018 A Survey of Flattening-Based Medical Visualization Techniques
abstract
Abstract In many areas of medicine, visualization research can help with task simplification, abstraction or complexity reduction. A common visualization approach is to facilitate parameterization techniques which flatten a usually 3D object into a 2D plane. Within this state of the art report (STAR), we review such techniques used in medical visualization and investigate how they can be classified with respect to the handled data and the underlying tasks. Many of these techniques are inspired by mesh parameterization algorithms which help to project a triangulation inℝ3to a simpler domain inℝ2. It is often claimed that this makes complex structures easier to understand and compare by humans and machines. Within this STAR we review such flattening techniques which have been developed for the analysis of the following medical entities: the circulation system, the colon, the brain, tumors, and bones. For each of these five application scenarios, we have analyzed the tasks and requirements, and classified the reviewed techniques with respect to a developed coding system. Furthermore, we present guidelines for the future development of flattening techniques in these areas.
Julian Kreiser, Monique Meuschke, Gabriel Mistelbauer, Bernhard Preim, Timo Ropinski
Comput. Graph. Forum2
2017 Glyph-Based Comparative Stress Tensor Visualization in Cerebral Aneurysms
abstract
Abstract We present the first visualization tool that enables a comparative depiction of structural stress tensor data for vessel walls of cerebral aneurysms. Such aneurysms bear the risk of rupture, whereas their treatment also carries considerable risks for the patient. Medical researchers emphasize the importance of analyzing the interaction of morphological and hemodynamic information for the patient‐specific rupture risk evaluation and treatment analysis. Tensor data such as the stress inside the aneurysm walls characterizes the interplay between the morphology and blood flow and seems to be an important rupture‐prone criterion. We use different glyph‐based techniques to depict local stress tensors simultaneously and compare their applicability to cerebral aneurysms in a user study. We thus offer medical researchers an effective visual exploration tool to assess the aneurysm rupture risk. We developed a GPU‐based implementation of our techniques with a flexible interactive data exploration mechanism. Our depictions are designed in collaboration with domain experts, and we provide details about the evaluation.
Monique Meuschke, Samuel Voß, Oliver Beuing, Bernhard Preim, Kai Lawonn
Comput. Graph. Forum1
2017 Combined Visualization of Vessel Deformation and Hemodynamics in Cerebral Aneurysms
abstract
We present the first visualization tool that combines patient-specific hemodynamics with information about the vessel wall deformation and wall thickness in cerebral aneurysms. Such aneurysms bear the risk of rupture, whereas their treatment also carries considerable risks for the patient. For the patient-specific rupture risk evaluation and treatment analysis, both morphological and hemodynamic data have to be investigated. Medical researchers emphasize the importance of analyzing correlations between wall properties such as the wall deformation and thickness, and hemodynamic attributes like the Wall Shear Stress and near-wall flow. Our method uses a linked 2.5D and 3D depiction of the aneurysm together with blood flow information that enables the simultaneous exploration of wall characteristics and hemodynamic attributes during the cardiac cycle. We thus offer medical researchers an effective visual exploration tool for aneurysm treatment risk assessment. The 2.5D view serves as an overview that comprises a projection of the vessel surface to a 2D map, providing an occlusion-free surface visualization combined with a glyph-based depiction of the local wall thickness. The 3D view represents the focus upon which the data exploration takes place. To support the time-dependent parameter exploration and expert collaboration, a camera path is calculated automatically, where the user can place landmarks for further exploration of the properties. We developed a GPU-based implementation of our visualizations with a flexible interactive data exploration mechanism. We designed our techniques in collaboration with domain experts, and provide details about the evaluation.
Monique Meuschke, Samuel Voß, Oliver Beuing, Bernhard Preim, Kai Lawonn
IEEE Trans. Vis. Comput. Graph.1
2016 Semi-automatic Vortex Flow Classification in 4D PC-MRI Data of the Aorta
abstract
Abstract We present an Aortic Vortex Classification (AVOCLA) that allows to classify vortices in the human aorta semi‐automatically. Current medical studies assume a strong relation between cardiovascular diseases and blood flow patterns such as vortices. Such vortices are extracted and manually classified according to specific, unstandardized properties. We employ an agglomerative hierarchical clustering to group vortex‐representing path lines as basis for the subsequent classification. Classes are based on the vortex' size, orientation and shape, its temporal occurrence relative to the cardiac cycle as well as its spatial position relative to the vessel course. The classification results are presented by a 2D and 3D visualization technique. To confirm the usefulness of both approaches, we report on the results of a user study. Moreover, AVOCLA was applied to 15 datasets of healthy volunteers and patients with different cardiovascular diseases. The results of the semi‐automatic classification were qualitatively compared to a manually generated ground truth of two domain experts considering the vortex number and five specific properties.
Monique Meuschke, Benjamin Köhler 0001, Uta Preim, Bernhard Preim, Kai Lawonn
Comput. Graph. Forum1
2014 Comparative Blood Flow Visualization for Cerebral Aneurysm Treatment Assessment
abstract
Abstract A pathological vessel dilation in the brain, termed cerebral aneurysm, bears a high risk of rupture, and is associated with a high mortality. In recent years, incidental findings of unruptured aneurysms have become more frequent, mainly due to advances in medical imaging. The pathological condition is often treated with a stent that diverts the blood flow from the aneurysm sac back to the original vessel. Prior to treatment, neuroradiologists need to decide on the optimal stent configuration and judge the long‐term rupture risk, for which blood flow information is essential. Modern patient‐specific simulations can model the hemodynamics for various stent configurations, providing important indicators to support the decision‐making process. However, the necessary visual analysis of these data becomes tedious and time‐consuming, because of the abundance of information. We introduce a comprehensive comparative visualization that integrates morphology with blood flow indicators to facilitate treatment assessment. To deal with the visual complexity, we propose a details‐on‐demand approach, combining established medical visualization techniques with innovative glyphs inspired by information visualization concepts. In an evaluation we have obtained informal feedback from domain experts, gauging the value of our visualization.
Roy van Pelt, Rocco Gasteiger, Kai Lawonn, Monique Meuschke, Bernhard Preim
Comput. Graph. Forum4