Meta-learning aims to uniformly sample homologous support-query pairs, characterized by the same categories and similar attributes, and extract useful inductive biases through identical network architectures. However, this identical network design results in over-semantic homogenization. To address this, we propose a novel homologous but heterogeneous network. By treating support-query pairs as dual perspectives, we introduce heterogeneous visual aggregation (HA) modules to enhance complementarity while preserving semantic commonality. To further reduce semantic noise and amplify the uniqueness of heterogeneous semantics, we design a heterogeneous transport (HT) module. Finally, we propose heterogeneous CLIP (HC) textual information to enhance the generalization capability of multimodal models. In the weakly-supervised few-shot semantic segmentation (WFSS) task, with only 1/24 of the parameters of existing state-of-the-art models, TLG achieves a 13.2% improvement on Pascal- $5{^{\text {i}}}$ and a 7.9% improvement on COCO- $20{^{\text {i}}}$ . To the best of our knowledge, TLG is also the first weakly-supervised (image-level) model that outperforms fully supervised (pixel-level) models under the same backbone architectures. The code is available at https://github.com/jarch-ma/TLG.

Few-shot learning aims to recognize novel concepts by leveraging prior knowledge learned from a few samples. However, for visually intensive tasks such as few-shot semantic segmentation, pixel-level annotations are time-consuming and costly. Therefore, in this paper, we utilize the more challenging image-level annotations and propose an adaptive frequency-aware network (AFANet) for weakly-supervised few-shot semantic segmentation (WFSS). Specifically, we first propose a cross-granularity frequency-aware module (CFM) that decouples RGB images into high-frequency and low-frequency distributions and further optimizes semantic structural information by realigning them. Unlike most existing WFSS methods using the textual information from the multi-modal language-vision model, e.g., CLIP, in an offline learning manner, we further propose a CLIP-guided spatial-adapter module (CSM), which performs spatial domain adaptive transformation on textual information through online learning, thus providing enriched cross-modal semantic information for CFM. Extensive experiments on the Pascal-5iand COCO-20idatasets demonstrate that AFANet has achieved state-of-the-art performance.

Protein s-nitrosylation (SNO) is one of the most important post-translational modifications and is formed by the covalent modification of nitric oxide and cysteine residues. Extensive studies have shown that SNO plays a pivotal role in the plant immune response and treating various major human diseases. In recent years, SNO sites have become a hot research topic. Traditional biochemical methods for SNO site identification are time-consuming and costly. In this study, we developed an economical and efficient SNO site prediction tool named Mul-SNO. Mul-SNO ensembled current popular and powerful deep learning model bidirectional long short-term memory (BiLSTM) and bidirectional encoder representations from Transformers (BERT). Compared with existing state-of-the-art methods, Mul-SNO obtained better ACC of 0.911 and 0.796 based on 10-fold cross-validation and independent data sets, respectively.