Cancer is a chaotic disease known as the plague of our age and there are many subtypes of the cancer. Cancer is commonly seen disorder and its mortality rate is very high. Therefore, many researchers have worked/studied on the cancer detection and threatment. To contribute cancer studies according to machine learning, we have presented a new generation convolutional neural network (CNN) termed ShortNeXt in this research. The presented ShortNeXt has inspired by ResNet, ConvNeXt and MobileNet architectures to use the advatnages these CNNs together. This model, which aims to extract robust feature map using convolution-based residual blocks, is named ShortNeXt because it incorporates more than one shortcut. The ShortNeXt architecture has four main stages and these stages are: (i) an input/stem, (ii) ShortNeXt, (iii) downsampling, and (iv) output. In this CNN architecture, convolution, batch normalization and the Gaussian Error Linear Unit (GELU) activation functions have been utilized. In this aspect, the implementation of the recommended ShortNeXt is simple. The stem stage uses a 4 × 4 sized convolution with stride 4 like ConvNeXt and Swin Transformer and this operation is named patchify operation. Additionally, a 2 × 2 patchify block has been used in the downsampling block. In the ShortNeXt block, an inverted bottleneck has been used, and both 1 × 1 and 3 × 3 convolution blocks are employed in the expansion phase. The output layer has increased the number of filters from 768 to 1280 by using pixel-wise convolution, drawing inspiration from MobileNetV2 and a final feature map with a length of 1280 has been obtained by deploying global average pooling (GAP). In the classification phase, fully connected and softmax operators have been used. To get comparative results about to the recommeden ShortNeXt, a publicly avaliable histopathological image dataset has been used and this dataset contains nine classes, and the proposed ShortNeXt has achieved 97.82% and 97.86% validation and test accuracy, respectively. The obtained results and findings openly showcases that ShortNeXt is an effective deep learning method for histopathological image classification for cancer detection/classification. • Novel triple-shortcut CNN achieves 98.2% accuracy with only 8.7M parameters. • Processes 714 histopathology images/second for efficient clinical deployment. • Outperforms transformers and ensemble methods on external validation data. • Grad-CAM visualization provides transparent diagnostic decision support.

Background and purpose Auscultatory sounds acquired using a stethoscope can offer clinical clues to the presence of cardiorespiratory diseases. In this work, we aimed to develop an accurate and lightweight model for disease detection using lung sounds. Method Our model comprises: (1) signal decomposition using a multilevel bidirectional wavelet transformation; (2) multilevel feature generation using a novel lattice-based graphene pattern to create minimum- and maximum directed graphs to extract textural features; (3) feature selection using iterative neighborhood component analysis; (4) classification using a standard shallow k-nearest neighbor function. We tested the model on a public 336-subject eight-class lung sound dataset. Model performance was reported for eight- and three-class diagnostic classification. Results Our model achieved accuracy rates exceeding 94 % for all classification tasks. The maximum distance path through the graphene pattern consistently outperformed the minimum distance path, indicating that significant amplitude transitions in respiratory sounds contain more discriminative information than regions of relative uniformity. Elements of the input signal and wavelet decomposition bands that contributed most to the selected feature vector were visualized, which enhanced model explainability and revealed that low-pass filtered wavelet coefficients, particularly the L3 band, were most informative for classification. Conclusion Our handcrafted computationally lightweight model yielded accurate and explainable results. These attributes facilitate potential integration into digital stethoscopes for point-of-care screening of respiratory diseases.

Background RNA viruses, including severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), are important human pathogens. Sequencing of the proteins produced by RNA viruses is essential for understanding disease pathogenesis and may have diagnostic and therapeutic implications. We aimed to develop an accurate and computationally efficient handcrafted feature engineering model for classifying the protein sequences of six pathogenic RNA viruses: SARS-CoV-2, influenza A, influenza B, influenza C, human respirovirus 3, and human immunodeficiency virus (HIV)-1. The first five cause primary respiratory infections; the last has some functional similarity with SARS-CoV-2, justifying the need for diagnostic differentiation. Materials and method We downloaded 14,787 protein sequences belonging to the six categories in FASTA format from the open-source National Center for Biotechnology Information database and transformed the sequences into numeric arrays. First, the signal was divided into overlapping blocks representing three amino acids. Tiny textural motif pattern, a new histogram-based feature extractor, was then applied to extract textural features using simple signum, lower, and upper ternary functions. 512 features were extracted for each protein sequence and fed to an iterative neighborhood component analysis function to select a study dataset-specific optimal number (34) of the most discriminative features for downstream classification using a shallow k-nearest neighbor classifier with 10-fold cross-validation. Novelties: An efficient linear time complexity is introduced for data classification, providing a robust classification approach, especially for complex datasets. Notably, this approach extends beyond the traditional binary classification focus, successfully distinguishing up to six distinct classes. Furthermore, a novel handcrafted feature extraction method is developed, significantly enhancing data analysis and yielding more precise results. Results The model attained 99.71% overall 6-class classification accuracy in a data subset and 99.85% for binary classification of SARS-CoV-2 vs. HIV-1, outperforming a similar published model. Conclusions Our simple model accurately classified the protein sequences of six pathogenic RNA viruses and can potentially be implemented in diagnostic applications to improve RNA virus disease screening.

Abstract Background Monkeypox is a viral disease caused by the monkeypox virus (MPV). A surge in monkeypox infection has been reported since early May 2022, and the outbreak has been classified as a global health emergency as the situation continues to worsen. Early and accurate detection of the disease is required to control its spread. Machine learning methods offer fast and accurate detection of COVID-19 from chest X-rays, and chest computed tomography (CT) images. Likewise, computer vision techniques can automatically detect monkeypoxes from digital images, videos, and other inputs. Objectives In this paper, we propose an automated monkeypox detection model as the first step toward controlling its global spread. Materials and method A new dataset comprising 910 open-source images classified into five categories (healthy, monkeypox, chickenpox, smallpox, and zoster zona) was created. A new deep feature engineering architecture was proposed, which contained the following components: (i) multiple nested patch division, (ii) deep feature extraction, (iii) multiple feature selection by deploying neighborhood component analysis (NCA), Chi2, and ReliefF selectors, (iv) classification using SVM with 10-fold cross-validation, (v) voted results generation by deploying iterative hard majority voting (IHMV) and (vi) selection of the best vector by a greedy algorithm. Results Our proposal attained a 91.87% classification accuracy on the collected dataset. This is the best result of our presented framework, which was automatically selected from 70 generated results. Conclusions The computed classification results and findings demonstrated that monkeypox could be successfully detected using our proposed automated model.

Abstract Asthma is a common disease. The clinical diagnosis is usually confirmed on a pulmonary function test, which is not always readily accessible. We aimed to develop a computationally lightweight handcrafted machine learning model for asthma detection based on cough sounds recorded using mobile phones. Toward this aim, we proposed a novel feature extractor based on a one-dimensional version of the published attractive-and-repulsive center-symmetric local binary pattern (1D-ARCSLBP), which we tested on a new cough sound dataset. We prospectively recorded cough sounds from 511 asthmatics and 815 non-asthmatic subjects (comprising mostly healthy volunteers), which yielded 1875 one-second cough sound segments for analysis. Our model comprised four steps: (i) preprocessing, in which speech signals and stop times (silent zones between coughs) were removed, leaving behind analyzable cough sound segments; (ii) feature extraction, in which tunable q-factor wavelet transformation was used to perform multilevel signal decomposition into wavelet subbands, allowing 1D-ARCSLBP to extract local low- and high-level features; (iii) feature selection, in which neighborhood component analysis was used to select the most discriminative features; and (iv) classification, in which a standard shallow cubic support vector machine was deployed to calculate binary classification results (asthma versus non-asthma) using tenfold and leave-one-subject-out cross-validations. Our model attained 98.24% and 96.91% accuracy rates with tenfold and leave-one-subject-out cross-validation strategies, respectively, and obtained a low-time complexity. The excellent results confirmed the feature extraction capability of 1D-ARCSLBP and the feasibility of the model being developed into a real-world application for asthma screening.

Abstract Automated urine sediment analysis has become an essential part of diagnosing, monitoring, and treating various diseases that affect the urinary tract and kidneys. However, manual analysis of urine sediment is time-consuming and prone to human bias, and hence there is a need for an automated urine sediment analysis systems using machine learning algorithms. In this work, we propose Swin-LBP, a handcrafted urine sediment classification model using the Swin transformer architecture and local binary pattern (LBP) technique to achieve high classification performance. The Swin-LBP model comprises five phases: preprocessing of input images using shifted windows-based patch division, six-layered LBP-based feature extraction, neighborhood component analysis-based feature selection, support vector machine-based calculation of six predicted vectors, and mode function-based majority voting of the six predicted vectors to generate four additional voted vectors. Our newly reconstructed urine sediment image dataset, consisting of 7 distinct classes, was utilized for training and testing our model. Our proposed model has several advantages over existing automated urinalysis systems. Firstly, we used a feature engineering model that enables high classification performance with linear complexity. This means that it can provide accurate results quickly and efficiently, making it an attractive alternative to time-consuming and biased manual urine sediment analysis. Additionally, our model outperformed existing deep learning models developed on the same source urine sediment image dataset, indicating its superiority in urine sediment classification. Our model achieved 92.60% accuracy for 7-class urine sediment classification, with an average precision of 92.05%. These results demonstrate that the proposed Swin-LBP model can provide a reliable and efficient solution for the diagnosis, surveillance, and therapeutic monitoring of various diseases affecting the kidneys and urinary tract. The proposed model's accuracy, speed, and efficiency make it an attractive option for clinical laboratories and healthcare facilities. In conclusion, the Swin-LBP model has the potential to revolutionize urine sediment analysis and improve patient outcomes in the diagnosis and treatment of urinary tract and kidney diseases.

The reconfiguration process in photovoltaic (PV) arrays is very important to obtain maximum power under partial shading conditions. Connection architecture of array for this process is changed according to status of non-uniform shadows. However, finding of best connection in big PV arrays is hard in real-time. In this paper, a new efficient and intelligent reconfiguration approach based on partitioning of array is proposed. The proposed approach is aimed to search best connection from possible connections in several small-sized array partitions obtained with decomposing according to location of shadows to carry out control task. Thus, search space of possible connections is considerably reduced for using in real time implementation of reconfiguration process in big size PV arrays. Efficiency, accuracy, and performance proposed reconfiguration approach has been verified for different size and shading conditions with comparative simulation results.