Multi-voxel pattern analysis (MVPA) learns predictive models from task-based functional magnetic resonance imaging (fMRI) data, for distinguishing when subjects are performing different cognitive tasks — e.g., watching movies or making decisions. MVPA works best with a well-designed feature set and an adequate sample size. However, most fMRI datasets are noisy, high-dimensional, expensive to collect, and with small sample sizes. Further, training a robust, generalized predictive model that can analyze homogeneous cognitive tasks provided by multi-site fMRI datasets has additional challenges. This paper proposes the Shared Space Transfer Learning (SSTL) as a novel transfer learning (TL) approach that can functionally align homogeneous multi-site fMRI datasets, and so improve the prediction performance in every site. SSTL first extracts a set of common features for all subjects in each site. It then uses TL to map these site-specific features to a site-independent shared space in order to improve the performance of the MVPA. SSTL uses a scalable optimization procedure that works effectively for high-dimensional fMRI datasets. The optimization procedure extracts the common features for each site by using a single-iteration algorithm and maps these site-specific common features to the site-independent shared space. We evaluate the effectiveness of the proposed method for transferring between various cognitive tasks. Our comprehensive experiments validate that SSTL achieves superior performance to other state-of-the-art analysis techniques.

The wisdom of crowds (WOCs), as a theory in the social science, gets a new paradigm in computer science. The WOC theory explains that the aggregate decision made by a group is often better than those of its individual members if specific conditions are satisfied. This paper presents a novel framework for unsupervised and semisupervised cluster ensemble by exploiting the WOC theory. We employ four conditions in the WOC theory, i.e., diversity, independency, decentralization, and aggregation, to guide both constructing of individual clustering results and final combination for clustering ensemble. First, independency criterion, as a novel mapping system on the raw data set, removes the correlation between features on our proposed method. Then, decentralization as a novel mechanism generates high quality individual clustering results. Next, uniformity as a new diversity metric evaluates the generated clustering results. Further, weighted evidence accumulation clustering method is proposed for the final aggregation without using thresholding procedure. Experimental study on varied data sets demonstrates that the proposed approach achieves superior performance to state-of-the-art methods.

Multivariate Pattern (MVP) classification can map different cognitive states to the brain tasks. One of the main challenges in MVP analysis is validating the generated results across subjects. However, analyzing multi-subject fMRI data requires accurate functional alignments between neuronal activities of different subjects, which can rapidly increase the performance and robustness of the final results. Hyperalignment (HA) is one of the most effective functional alignment methods, which can be mathematically formulated by the Canonical Correlation Analysis (CCA) methods. Since HA mostly uses the unsupervised CCA techniques, its solution may not be optimized for MVP analysis. By incorporating the idea of Local Discriminant Analysis (LDA) into CCA, this paper proposes Local Discriminant Hyperalignment (LDHA) as a novel supervised HA method, which can provide better functional alignment for MVP analysis. Indeed, the locality is defined based on the stimuli categories in the train-set, where the correlation between all stimuli in the same category will be maximized and the correlation between distinct categories of stimuli approaches to near zero. Experimental studies on multi-subject MVP analysis confirm that the LDHA method achieves superior performance to other state-of-the-art HA algorithms.

This paper proposes Deep Hyperalignment (DHA) as a regularized, deep extension, scalable Hyperalignment (HA) method, which is well-suited for applying functional alignment to fMRI datasets with nonlinearity, high-dimensionality (broad ROI), and a large number of subjects. Unlink previous methods, DHA is not limited by a restricted fixed kernel function. Further, it uses a parametric approach, rank-m Singular Value Decomposition (SVD), and stochastic gradient descent for optimization. Therefore, DHA has a suitable time complexity for large datasets, and DHA does not require the training data when it computes the functional alignment for a new subject. Experimental studies on multi-subject fMRI analysis confirm that the DHA method achieves superior performance to other state-of-the-art HA algorithms.

Multivariate Pattern (MVP) classification holds enormous potential for decoding visual stimuli in the human brain by employing task-based fMRI data sets. There is a wide range of challenges in the MVP techniques, i.e. decreasing noise and sparsity, defining effective regions of interest (ROIs), visualizing results, and the cost of brain studies. In overcoming these challenges, this paper proposes a novel model of neural representation, which can automatically detect the active regions for each visual stimulus and then utilize these anatomical regions for visualizing and analyzing the functional activities. Therefore, this model provides an opportunity for neuroscientists to ask this question: what is the effect of a stimulus on each of the detected regions instead of just study the fluctuation of voxels in the manually selected ROIs. Moreover, our method introduces analyzing snapshots of brain image for decreasing sparsity rather than using the whole of fMRI time series. Further, a new Gaussian smoothing method is proposed for removing noise of voxels in the level of ROIs. The proposed method enables us to combine different fMRI data sets for reducing the cost of brain studies. Experimental studies on 4 visual categories (words, consonants, objects and nonsense photos) confirm that the proposed method achieves superior performance to state-of-the-art methods.

Clustering explores meaningful patterns in the non-labeled data sets. Cluster Ensemble Selection (CES) is a new approach, which can combine individual clustering results for increasing the performance of the final results. Although CES can achieve better final results in comparison with individual clustering algorithms and cluster ensemble methods, its performance can be dramatically affected by its consensus diversity metric and thresholding procedure. There are two problems in CES: 1) most of the diversity metrics is based on heuristic Shannon's entropy and 2) estimating threshold values are really hard in practice. The main goal of this paper is proposing a robust approach for solving the above mentioned problems. Accordingly, this paper develops a novel framework for clustering problems, which is called Weighted Spectral Cluster Ensemble (WSCE), by exploiting some concepts from community detection arena and graph based clustering. Under this framework, a new version of spectral clustering, which is called Two Kernels Spectral Clustering, is used for generating graphs based individual clustering results. Further, by using modularity, which is a famous metric in the community detection, on the transformed graph representation of individual clustering results, our approach provides an effective diversity estimation for individual clustering results. Moreover, this paper introduces a new approach for combining the evaluated individual clustering results without the procedure of thresholding. Experimental study on varied data sets demonstrates that the prosed approach achieves superior performance to state-of-the-art methods.

The Wisdom of Crowds is a phenomenon described in social science that suggests four criteria applicable to groups of people. It is claimed that, if these criteria are satisfied, then the aggregate decisions made by a group will often be better than those of its individual members. Inspired by this concept, we present a novel feedback framework for the cluster ensemble problem, which we call Wisdom of Crowds Cluster Ensemble (WOCCE). Although many conventional cluster ensemble methods focusing on diversity have recently been proposed, WOCCE analyzes the conditions necessary for a crowd to exhibit this collective wisdom. These include decentralization criteria for generating primary results, independence criteria for the base algorithms, and diversity criteria for the ensemble members. We suggest appropriate procedures for evaluating these measures, and propose a new measure to assess the diversity. We evaluate the performance of WOCCE against some other traditional base algorithms as well as state-of-the-art ensemble methods. The results demonstrate the efficiency of WOCCE's aggregate decision-making compared to other algorithms.