Monitoring advertising around controversial issues is an important step in ensuring accountability and transparency of political processes. To that end, we use the Facebook Ads Library to collect 2312 migration-related advertising campaigns in Italy over one year. Our pro- and anti-immigration classifier (F1=0.85) reveals a partisan divide among the major Italian political parties, with anti-immigration ads accounting for nearly 15M impressions. Although composing 47.6% of all migration-related ads, anti-immigration ones receive 65.2% of impressions. We estimate that about two thirds of all captured campaigns use some kind of demographic targeting by location, gender, or age. We find sharp divides by age and gender: for instance, anti-immigration ads from major parties are 17% more likely to be seen by a male user than a female. Unlike pro-migration parties, we find that anti-immigration ones reach a similar demographic to their own voters. However their audience change with topic: an ad from anti-immigration parties is 24% more likely to be seen by a male user when the ad speaks about migration, than if it does not. Furthermore, the viewership of such campaigns tends to follow the volume of mainstream news around immigration, supporting the theory that political advertisers try to “ride the wave” of current news. We conclude with policy implications for political communication: since the Facebook Ads Library does not allow to distinguish between advertisers intentions and algorithmic targeting, we argue that more details should be shared by platforms regarding the targeting configuration of socio-political campaigns.

Vaccine hesitancy is considered as one of the leading causes for the resurgence of vaccine preventable diseases. A non-negligible minority of parents does not fully adhere to the recommended vaccination schedule, leading their children to be partially immunized and at higher risk of contracting vaccine preventable diseases. Here, we leverage more than one million comments of 201,986 users posted from March 2008 to April 2019 on the public online forum BabyCenter US to learn more about such parents. For 32% with geographic location, we find the number of mapped users for each US state resembling the census population distribution with good agreement. We employ Natural Language Processing to identify 6884 and 10,131 users expressing their intention of following the recommended and alternative vaccination schedule, respectively RSUs and ASUs. From the analysis of their activity on the forum we find that ASUs have distinctly different interests and previous experiences with vaccination than RSUs. In particular, ASUs are more likely to follow groups focused on alternative medicine, are two times more likely to have experienced adverse events following immunization, and to mention more serious adverse reactions such as seizure or developmental regression. Content analysis of comments shows that the resources most frequently shared by both groups point to governmental domains (.gov). Finally, network analysis shows that RSUs and ASUs communicate between each other (indicating the absence of echo chambers), however with the latter group being more endogamic and favoring interactions with other ASUs. While our findings are limited to the specific platform analyzed, our approach may provide additional insights for the development of campaigns targeting parents on digital platforms.

BACKGROUND: Emerging and re-emerging infectious diseases such as Zika, SARS, ncovid19 and Pertussis, pose a compelling challenge for epidemiologists due to their significant impact on global public health. In this context, computational models and computer simulations are one of the available research tools that epidemiologists can exploit to better understand the spreading characteristics of these diseases and to decide on vaccination policies, human interaction controls, and other social measures to counter, mitigate or simply delay the spread of the infectious diseases. Nevertheless, the construction of mathematical models for these diseases and their solutions remain a challenging tasks due to the fact that little effort has been devoted to the definition of a general framework easily accessible even by researchers without advanced modelling and mathematical skills. RESULTS: In this paper we describe a new general modeling framework to study epidemiological systems, whose novelties and strengths are: (1) the use of a graphical formalism to simplify the model creation phase; (2) the implementation of an R package providing a friendly interface to access the analysis techniques implemented in the framework; (3) a high level of portability and reproducibility granted by the containerization of all analysis techniques implemented in the framework; (4) a well-defined schema and related infrastructure to allow users to easily integrate their own analysis workflow in the framework. Then, the effectiveness of this framework is showed through a case of study in which we investigate the pertussis epidemiology in Italy. CONCLUSIONS: We propose a new general modeling framework for the analysis of epidemiological systems, which exploits Petri Net graphical formalism, R environment, and Docker containerization to derive a tool easily accessible by any researcher even without advanced mathematical and computational skills. Moreover, the framework was implemented following the guidelines defined by Reproducible Bioinformatics Project so it guarantees reproducible analysis and makes simple the developed of new user-defined workflows.

In this work, we aim to determine the main factors driving self-initiated behavioral changes during the seasonal flu.To this end, we designed and deployed a questionnaire via Influweb, a Web platform for participatory surveillance in Italy, during the 2017 -18 and 2018 -19 seasons.We collected 599 surveys completed by 434 users.The data provide socio-demographic information, level of concerns about the flu, past experience with illnesses, and the type of behavioral changes voluntarily implemented by each participant.We describe each response with a set of features and divide them in three target categories.These describe those that report i) no (26%), ii) only moderately (36%), iii) significant (38%) changes in behaviors.In these settings, we adopt machine learning algorithms to investigate the extent to which target variables can be predicted by looking only at the set of features.Notably, 66% of the samples in the category describing more significant changes in behaviors are correctly classified through Gradient Boosted Trees.Furthermore, we investigate the importance of each feature in the classification task and uncover complex relationships between individuals' characteristics and their attitude towards behavioral change.We find that intensity, recency of past illnesses, perceived susceptibility to and perceived severity of an infection are the most significant features in the classification task and are associated to significant changes in behaviors.Overall, the research contributes to the small set of empirical studies devoted to the data-driven characterization of behavioral changes induced by infectious diseases. Author summaryHuman behavior and infectious diseases are linked by a feedback loop.While individuals might change their behavior as a response to an epidemic, such changes might influence the spreading itself.So far, our understanding and characterization of behavioral changes induced by diseases has been strongly limited by the lack of empirical data.As result, the vast majority of research has been focused on theoretical, what if, scenarios.In this work, we collected a unique dataset comprised of 599 surveys submitted by 434 users to the participatory surveillance platform Influweb over the 2017 -18 and 2018 -19 flu seasons.

In recent years, many studies have drawn attention to the important role of collective awareness and human behaviour during epidemic outbreaks. A number of modelling efforts have investigated the interaction between the disease transmission dynamics and human behaviour change mediated by news coverage and by information spreading in the population. Yet, given the scarcity of data on public awareness during an epidemic, few studies have relied on empirical data. Here, we use fine-grained, geo-referenced data from three online sources-Wikipedia, the GDELT Project and the Internet Archive-to quantify population-scale information seeking about the 2016 Zika virus epidemic in the U.S., explicitly linking such behavioural signal to epidemiological data. Geo-localized Wikipedia pageview data reveal that visiting patterns of Zika-related pages in Wikipedia were highly synchronized across the United States and largely explained by exposure to national television broadcast. Contrary to the assumption of some theoretical epidemic models, news volume and Wikipedia visiting patterns were not significantly correlated with the magnitude or the extent of the epidemic. Attention to Zika, in terms of Zika-related Wikipedia pageviews, was high at the beginning of the outbreak, when public health agencies raised an international alert and triggered media coverage, but subsequently exhibited an activity profile that suggests nonlinear dependencies and memory effects in the relation between information seeking, media pressure, and disease dynamics. This calls for a new and more general modelling framework to describe the interaction between media exposure, public awareness and disease dynamics during epidemic outbreaks.

Seasonal influenza surveillance is usually carried out by sentinel general practitioners (GPs) who compile weekly reports based on the number of influenza-like illness (ILI) clinical cases observed among visited patients. This traditional practice for surveillance generally presents several issues, such as a delay of one week or more in releasing reports, population biases in the health-seeking behaviour, and the lack of a common definition of ILI case. On the other hand, the availability of novel data streams has recently led to the emergence of non-traditional approaches for disease surveillance that can alleviate these issues. In Europe, a participatory web-based surveillance system called Influenzanet represents a powerful tool for monitoring seasonal influenza epidemics thanks to aid of self-selected volunteers from the general population who monitor and report their health status through Internet-based surveys, thus allowing a real-time estimate of the level of influenza circulating in the population. In this work, we propose an unsupervised probabilistic framework that combines time series analysis of self-reported symptoms collected by the Influenzanet platforms and performs an algorithmic detection of groups of symptoms, called syndromes. The aim of this study is to show that participatory web-based surveillance systems are capable of detecting the temporal trends of influenza-like illness even without relying on a specific case definition. The methodology was applied to data collected by Influenzanet platforms over the course of six influenza seasons, from 2011-2012 to 2016-2017, with an average of 34,000 participants per season. Results show that our framework is capable of selecting temporal trends of syndromes that closely follow the ILI incidence rates reported by the traditional surveillance systems in the various countries (Pearson correlations ranging from 0.69 for Italy to 0.88 for the Netherlands, with the sole exception of Ireland with a correlation of 0.38). The proposed framework was able to forecast quite accurately the ILI trend of the forthcoming influenza season (2016-2017) based only on the available information of the previous years (2011-2016). Furthermore, to broaden the scope of our approach, we applied it both in a forecasting fashion to predict the ILI trend of the 2016-2017 influenza season (Pearson correlations ranging from 0.60 for Ireland and UK, and 0.85 for the Netherlands) and also to detect gastrointestinal syndrome in France (Pearson correlation of 0.66). The final result is a near-real-time flexible surveillance framework not constrained by any specific case definition and capable of capturing the heterogeneity in symptoms circulation during influenza epidemics in the various European countries.

We provide an overview of the DSAA 2018 Data Science for Social Good special session, its aims and contributions.

Traditional surveillance of seasonal influenza is generally affected by reporting lags of at least one week and by continuous revisions of the numbers initially released. As a consequence, influenza forecasts are often limited by the time required to collect new and accurate data. On the other hand, the availability of novel data streams for disease detection can help in overcoming these issues by capturing an additional surveillance signal that can be used to complement data collected by public health agencies. In this study, we investigate how combining both traditional and participatory Web-based surveillance data can provide accurate predictions for seasonal influenza in real-time fashion. To this aim, we use two data sources available in Italy from two different monitoring systems: traditional surveillance data based on sentinel doctors reports and digital surveillance data deriving from a participatory system that monitors the influenza activity through Internet-based surveys. We integrate such digital component in a linear autoregressive exogenous (ARX) model based on traditional surveillance data and evaluate its predictive ability over the course of four influenza seasons in Italy, from 2012-2013 to 2015-2016, for each of the four weekly time horizons. Our results show that by using data extracted from a Web-based participatory surveillance system, which are usually available one week in advance with respect to traditional surveillance, it is possible to obtain accurate weekly predictions of influenza activity at national level up to four weeks in advance. Compared to a model that is only based on data from sentinel doctors, our approach significantly improves real-time forecasts of influenza activity, by increasing the Pearson's correlation up to 30% and by reducing the Mean Absolute Error up to 43% for the four weekly time horizons.

The availability of novel digital data streams that can be used as proxy for monitoring infectious disease incidence is ushering in a new era for real-time forecast approaches to disease spreading. Here, we propose the first seasonal influenza forecast framework based on a stochastic, spatially structured mechanistic model (individual level microsimulation) initialized with geo-localized microblogging data. The framework provides for more than 600 census areas in the United States, Italy and Spain, the initial conditions for a stochastic epidemic computational model that generates an ensemble of forecasts for the main indicators of the epidemic season: peak time and intensity. We evaluate the forecasts accuracy and reliability by comparing the results with the data from the official influenza surveillance systems in the US, Italy and Spain in the seasons 2014/15 and 2015/16. In all countries studied, the proposed framework provides reliable results with leads of up to 6 weeks that became more stable and accurate with progression of the season. The results for the United States have been generated in real-time in the context of the Centers for Disease Control and Prevention ``Forecasting the Influenza Season Challenge''. A characteristic feature of the mechanistic modeling approach is in the explicit estimate of key epidemiological parameters relevant for public health decision-making that cannot be achieved with statistical models that do not consider the disease dynamic. Furthermore, the presented framework allows the fusion of multiple data streams in the initialization stage and can be enriched with census, weather and socioeconomic data.