General movements (GMs) are part of the spontaneous movement repertoire and are present from early fetal life onwards up to age five months. GMs are connected to infants' neurological development and can be qualitatively assessed via the General Movement Assessment (GMA). In particular, between the age of three to five months, typically developing infants produce Fidgety Movements (FM) and their absence provides strong evidence for the presence of cerebral palsy (CP). To improve accessibility to the GMA, automated GMA solutions have been a key research area with proposed models becoming increasingly more accurate and interpretable. However, current models cannot gauge their ability to make decisions, which may lead to overconfident mistakes. To address this issue, we propose a Deep learning-based approach that not only classifies movements as fidgety or non-fidgety but also selectively abstains from classification when uncertain. Through two novel regularization losses, our model maintains a balanced coverage across the two movement types, which prevents bias toward an easy-to-classify subset of movements. We show that our proposed model learns to gauge its own confidence on movement classification, and our proposed regularization losses effectively ensure that the model maintains a similar confidence across movement types. We also show that the local movement abstentions have little impact on the video-level coverage and that relying on the most confident predictions improves the video-level performance.

Typically developing infants, between the corrected age of 9-20 weeks, produce fidgety movements. These movements can be identified with the General Movement Assessment, but their identification requires trained professionals to conduct the assessment from video recordings. Since trained professionals are expensive and their demand may be higher than their availability, computer vision-based solutions have been developed to assist practitioners. However, most solutions to date treat the problem as a direct mapping from video to infant status, without modeling fidgety movements throughout the video. To address that, we propose to directly model infants' short movements and classify them as fidgety or non-fidgety. In this way, we model the explanatory factor behind the infant's status and improve model interpretability. The issue with our proposal is that labels for an infant's short movements are not available, which precludes us to train such a model. We overcome this issue with active learning. Active learning is a framework that minimizes the amount of labeled data required to train a model, by only labeling examples that are considered "informative" to the model. The assumption is that a model trained on informative examples reaches a higher performance level than a model trained with randomly selected examples. We validate our framework by modeling the movements of infants' hips on two representative cohorts: typically developing and at-risk infants. Our results show that active learning is suitable to our problem and that it works adequately even when the models are trained with labels provided by a novice annotator.

Fidgety movements occur in infants between the age of 9 to 20 weeks post-term, and their absence are a strong indicator that an infant has cerebral palsy. Prechtl's General Movement Assessment method evaluates whether an infant has fidgety movements, but requires a trained expert to conduct it. Timely evaluation facilitates early interventions, and thus computer-based methods have been developed to aid domain experts. However, current solutions rely on complex models or high-dimensional representations of the data, which hinder their interpretability and generalization ability. To address that we propose [Formula: see text], a method that detects fidgety movements and uses them towards an assessment of the quality of an infant's general movements. [Formula: see text] is true to the domain expert process, more accurate, and highly interpretable due to its fine-grained scoring system. The main idea behind [Formula: see text] is to specify signal properties of fidgety movements that are measurable and quantifiable. In particular, we measure the movement direction variability of joints of interest, for movements of small amplitude in short video segments. [Formula: see text] also comprises a strategy to reduce those measurements to a single score that quantifies the quality of an infant's general movements; the strategy is a direct translation of the qualitative procedure domain experts use to assess infants. This brings [Formula: see text] closer to the process a domain expert applies to decide whether an infant produced enough fidgety movements. We evaluated [Formula: see text] on the largest clinical dataset reported, where it showed to be interpretable and more accurate than many methods published to date.

A 324-Mbit/s electrical regenerator module intended for undersea optical-fiber systems is described. It has a sensitivity of 20 mV peak to peak, at which the total jitter is 3.3° rms, a low figure achieved by close attention to balance at chip and circuit board level. Timing phase adjustment is by means of a single select-on-test resistor, which enables the timing to be optimized quicker and more accurately than by conventional means. The regenerator functions are realized using four chips in the proven ECL-40 technology. This number reduces to three if a 28-pin chip carrier is used. The power consumption of these chips totals 1.3 W. The module incorporates a novel method ("flip-chip") of mounting SAW filters which is mechanically robust without the use of organic compounds, and which improves SAW performance by the virtual elimination of electromagnetic breakthrough.