The advancement of quantum computing into the utility scale requires compilation frameworks that can effectively manage the discrepancy between high-level algorithmic intent and the low-level physical constraints of contemporary hardware. Quantum circuit partitioning is a pivotal stage in this compilation pipeline, particularly when leveraging high-performance synthesis tools that are computationally bounded by the number of qubits. Existing partitioning approaches, such as ScanPartitioner [19] and QuickPartitioner [21], while effective, do not leverage structural patterns in circuits, limiting their ability to make globally informed local partitioning decisions. To address this gap, we propose a novel structural-aware quantum circuit partitioning method using a reinforcement learning (RL) framework that harnesses global circuit knowledge to guide local partitioning decisions, enabling more optimization opportunities at the sub-circuit level. Experimental results on benchmark circuits transpiled to satisfy IBM quantum hardware constraints show that our approach reduces the native two-qubit gate count compared to existing quantum circuit partitioners (ScanPartitioner and QuickPartitioner) with an average two-qubit gate reduction of 18.55% over baselines. This research establishes a scalable and robust methodology for partitioning quantum circuits, bridging the gap between exact and approximate synthesis in the Noisy Intermediate-Scale Quantum (NISQ) era and beyond.

Quantum circuit optimization can unlock the full potential of quantum computers for scalable and practical applications. In particular, quantum circuit re-synthesis methods enable significant reductions in gate count by applying approximate unitary synthesis locally at the subcircuit level. Despite these improvements, such optimization techniques rely on random seeds, which can lead to variability in performance across different runs. This inherent randomness raises important questions about the stability and reproducibility of approximate re-synthesis methods.