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Sean La

dblp:192/1333 · DBLP profile ↗
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1ranked-venue papers
1as first author
0since 2021 · last 2017
0000-0002-1000-9514ORCID · reported

Domains — the database's venue-derived domains; a paper can count in several

Applied, interdisciplinary, general and emerging computing · 1 · 1 first-author

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
1 paper
Bioinformatics and computational biology · 100%

Topics — the 2 heaviest of 2, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Bioinformatics and computational biology › sequence analysis
long-read sequencing
0.312017
LRCstats, a tool for evaluating long reads correction methods · Bioinform. 2017
Bioinformatics and computational biology › sequence analysis › sequencing error correction
long-read error correction
0.112017
LRCstats, a tool for evaluating long reads correction methods · Bioinform. 2017

Methods — techniques the papers use, named apart from their topics

read simulation alignment · 0.3
YearPublicationVenuePosition
2017 LRCstats, a tool for evaluating long reads correction methods
abstract
MOTIVATION: Third-generation sequencing (TGS) platforms that generate long reads, such as PacBio and Oxford Nanopore technologies, have had a dramatic impact on genomics research. However, despite recent improvements, TGS reads suffer from high-error rates and the development of read correction methods is an active field of research. This motivates the need to develop tools that can evaluate the accuracy of noisy long reads correction tools. RESULTS: We introduce LRCstats, a tool that measures the accuracy of long reads correction tools. LRCstats takes advantage of long reads simulators that provide each simulated read with an alignment to the reference genome segment they originate from, and does not rely on a step of mapping corrected reads onto the reference genome. This allows for the measurement of the accuracy of the correction while being consistent with the actual errors introduced in the simulation process used to generate noisy reads. We illustrate the usefulness of LRCstats by analyzing the accuracy of four hybrid correction methods for PacBio long reads over three datasets. AVAILABILITY AND IMPLEMENTATION: https://github.com/cchauve/lrcstats. CONTACT: [email protected] or [email protected]. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Sean La, Ehsan Haghshenas, Cédric Chauve
Bioinform.1