For any ɛ > 0, we give a simple, deterministic (4+ɛ)-approximation algorithm for the Nash social welfare (NSW) problem under submodular valuations. We also consider the asymmetric variant of the problem, where the objective is to maximize the weighted geometric mean of agents’ valuations, and give an e(ω + 2 + ɛ)-approximation if the ratio between the largest weight and the average weight is at most ω. We also show that the 1/2-EFX envy-freeness property can be attained simultaneously with a constant-factor approximation. More precisely, we can find an allocation in polynomial time that is both 1/2-EFX and an (8+ɛ)-approximation to the symmetric NSW problem under submodular valuations.

Abstract In the Time-Windows Unsplittable Flow on a Path problem ( twUFP ) we are given a resource whose available amount changes over a given time interval (modeled as the edge-capacities of a given path G ) and a collection of tasks. Each task is characterized by a demand (of the considered resource), a profit, an integral processing time, and a time window. Our goal is to compute a maximum profit subset of tasks and schedule them non-preemptively within their respective time windows, such that the total demand of the tasks using each edge e is at most the capacity of e . We prove that twUFP is $$\textsf{APX}$$ APX -hard which contrasts the setting of the problem without time windows, i.e., Unsplittable Flow on a Path, for which a PTAS was recently discovered [Grandoni, Mömke, Wiese, STOC 2022]. Then, we present a quasi-polynomial-time $$2+\varepsilon $$ 2 + ε approximation for twUFP under resource augmentation. Our approximation ratio improves to $$1+\varepsilon $$ 1 + ε if all tasks’ time windows are identical. Our $$\textsf{APX}$$ APX -hardness holds also for this special case and, hence, rules out such a PTAS (and even a QPTAS, unless $$\textsf{NP}\subseteq \textrm{DTIME}(n^{\textrm{poly}(\log n)})$$ NP ⊆ DTIME ( n poly ( log n ) ) ) without resource augmentation.

In the maximum independent set of convex polygons problem, we are given a set of $n$ convex polygons in the plane with the objective of selecting a maximum cardinality subset of non-overlapping polygons. Here we study a special case of the problem where the edges of the polygons can take at most $d$ fixed directions. We present an $8d/3$-approximation algorithm for this problem running in time $O((nd)^{O(d4^d)})$. The previous-best polynomial-time approximation (for constant $d$) was a classical $n^\varepsilon$ approximation by Fox and Pach [SODA'11] that has recently been improved to a $OPT^{\varepsilon}$-approximation algorithm by Cslovjecsek, Pilipczuk and Węgrzycki [SODA '24], which also extends to an arbitrary set of convex polygons. Our result builds on, and generalizes the recent constant factor approximation algorithms for the maximum independent set of axis-parallel rectangles problem (which is a special case of our problem with $d=2$) by Mitchell [FOCS'21] and Gálvez, Khan, Mari, Mömke, Reddy, and Wiese [SODA'22].

For any >0, we give a simple, deterministic (4+)-approximation algorithm for the Nash social welfare (NSW) problem under submodular valuations. The previous best approximation factor was 380 via a randomized algorithm. We also consider the asymmetric variant of the problem, where the objective is to maximize the weighted geometric mean of agents’ valuations, and give an (ω + 2 + ) -approximation if the ratio between the largest weight and the average weight is at most ω.

We characterize a rich class of valuated matroids, called R-minor valuated matroids that includes the indicator functions of matroids, and is closed under operations such as taking minors, duality, and induction by network. We exhibit a family of valuated matroids that are not R-minor based on sparse paving matroids. Valuated matroids are inherently related to gross substitute valuations in mathematical economics. By the same token we refute the Matroid Based Valuation Conjecture by Ostrovsky and Paes Leme (Theoretical Economics 2015) asserting that every gross substitute valuation arises from weighted matroid rank functions by repeated applications of merge and endowment operations. Our result also has implications in the context of Lorentzian polynomials: it reveals the limitations of known construction operations.

A multi-assembly problem asks to reconstruct multiple genomic sequences from mixed reads sequenced from all of them. Standard formulations of such problems model a solution as a path cover in a directed acyclic graph, namely a set of paths that together cover all vertices of the graph. Since multi-assembly problems admit multiple solutions in practice, we consider an approach commonly used in standard genome assembly: output only partial solutions (contigs, or safe paths), that appear in all path cover solutions. We study constrained path covers, a restriction on the path cover solution that incorporate practical constraints arising in multi-assembly problems. We give efficient algorithms finding all maximal safe paths for constrained path covers. We compute the safe paths of splicing graphs constructed from transcript annotations of different species. Our algorithms run in less than 15 seconds per species and report RNA contigs that are over 99% precise and are up to 8 times longer than unitigs. Moreover, RNA contigs cover over 70% of the transcripts and their coding sequences in most cases. With their increased length to unitigs, high precision, and fast construction time, maximal safe paths can provide a better base set of sequences for transcript assembly programs.

We consider the Arrow--Debreu exchange market model under the assumption that the agents' demands satisfy the weak gross substitutes (WGS) property. We present a simple auction algorithm that obtains an approximate market equilibrium for WGS demands assuming the availability of a price update oracle. We exhibit specific implementations of such an oracle for WGS demands with bounded price elasticities and for Gale demand systems. As an application of our result, we obtain an efficient algorithm to find an approximate spending-restricted market equilibrium for WGS demands, a model that has been recently introduced as a continuous relaxation of the Nash social welfare (NSW) problem. This leads to a polynomial-time constant factor approximation algorithm for the NSW problem with capped additive separable piecewise linear utility functions; only a pseudopolynomial approximation algorithm was known for this setting previously.

The Nash social welfare problem asks for an allocation of indivisible items to agents in order to maximize the geometric mean of agents' valuations. We give an overview of the constant-factor approximation algorithm for the problem when agents have Rado valuations [Garg et al. 2021]. Rado valuations are a common generalization of the assignment (OXS) valuations and weighted matroid rank functions. Our approach also gives the first constant-factor approximation algorithm for the asymmetric Nash social welfare problem under the same valuations, provided that the maximum ratio between the weights is bounded by a constant.

The class of even-hole-free graphs is very similar to the class of perfect graphs, and was indeed a cornerstone in the tools leading to the proof of the Strong Perfect Graph Theorem. However, the complexity of computing a maximum independent set (MIS) is a long-standing open question in even-hole-free graphs. From the hardness point of view, MIS is W[1]-hard in the class of graphs without induced 4-cycle (when parameterized by the solution size). Halfway of these, we show in this paper that MIS is FPT when parameterized by the solution size in the class of even-hole-free graphs. The main idea is to apply twice the well-known technique of augmenting graphs to extend some initial independent set.

MOTIVATION: Discovering the evolution of a tumor may help identify driver mutations and provide a more comprehensive view on the history of the tumor. Recent studies have tackled this problem using multiple samples sequenced from a tumor, and due to clinical implications, this has attracted great interest. However, such samples usually mix several distinct tumor subclones, which confounds the discovery of the tumor phylogeny. RESULTS: We study a natural problem formulation requiring to decompose the tumor samples into several subclones with the objective of forming a minimum perfect phylogeny. We propose an Integer Linear Programming formulation for it, and implement it into a method called MIPUP. We tested the ability of MIPUP and of four popular tools LICHeE, AncesTree, CITUP, Treeomics to reconstruct the tumor phylogeny. On simulated data, MIPUP shows up to a 34% improvement under the ancestor-descendant relations metric. On four real datasets, MIPUP's reconstructions proved to be generally more faithful than those of LICHeE. AVAILABILITY AND IMPLEMENTATION: MIPUP is available at https://github.com/zhero9/MIPUP as open source. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Motivated by applications in cancer genomics and following the work of Hajirasouliha and Raphael (WABI 2014), Hujdurović et al. (IEEE TCBB, 2018) introduced the minimum conflict-free row split (MCRS) problem: split each row of a given binary matrix into a bitwise OR of a set of rows so that the resulting matrix corresponds to a perfect phylogeny and has the minimum possible number of rows among all matrices with this property. Hajirasouliha and Raphael also proposed the study of a similar problem, in which the task is to minimize the number of distinct rows of the resulting matrix. Hujdurović et al. proved that both problems are NP-hard, gave a related characterization of transitively orientable graphs, and proposed a polynomial-time heuristic algorithm for the MCRS problem based on coloring cocomparability graphs. We give new, more transparent formulations of the two problems, showing that the problems are equivalent to two optimization problems on branchings in a derived directed acyclic graph. Building on these formulations, we obtain new results on the two problems, including (1) a strengthening of the heuristic by Hujdurović et al. via a new min-max result in digraphs generalizing Dilworth’s theorem, which may be of independent interest; (2) APX-hardness results for both problems; (3) approximation algorithms; and (4) exponential-time algorithms solving the two problems to optimality faster than the naïve brute-force approach. Our work relates to several well-studied notions in combinatorial optimization: chain partitions in partially ordered sets, laminar hypergraphs, and (classical and weighted) colorings of graphs.