Anomaly detection (AD) identifies outliers for applications like defect and lesion detection. While CLIP shows promise for zero-shot AD tasks due to its strong generalization capabilities, its inherent Anomaly-Unawareness leads to limited discrimination between normal and abnormal features. To address this problem, we propose Anomaly-Aware CLIP (AA-CLIP), which enhances CLIP's anomaly discrimination ability in both text and visual spaces while preserving its generalization capability. AA-CLIP is achieved through a straightforward yet effective two-stage approach: it first creates anomaly-aware text anchors to differentiate normal and abnormal semantics clearly, then aligns patch-level visual features with these anchors for precise anomaly localization. This two-stage strategy, with the help of residual adapters, gradually adapts CLIP in a controlled manner, achieving effective AD while maintaining CLIP's class knowledge. Extensive experiments validate AA-CLIP as a resource-efficient solution for zero-shot AD tasks, achieving state-of-the-art results in industrial and medical applications. The code is available at https://github.com/Mwxinnn/AA-CLIP.

Sparse-view computed tomography (CT) reduces radiation exposure by acquiring fewer projections, making it a valuable tool in clinical scenarios where low-dose radiation is essential. However, this often results in increased noise and artifacts due to limited data. In this paper we propose a novel 3D Gaussian representation (3DGR) based method for sparse-view CT reconstruction. Inspired by recent success in novel view synthesis driven by 3D Gaussian splatting, we leverage the efficiency and expressiveness of 3D Gaussian representation as an alternative to implicit neural representation. To unleash the potential of 3DGR for CT imaging scenario, we propose two key innovations: (i) FBP-image-guided Guassian initialization and (ii) efficient integration with a differentiable CT projector. Extensive experiments and ablations on diverse datasets demonstrate the proposed 3DGR-CT consistently outperforms state-of-the-art counterpart methods, achieving higher reconstruction accuracy with faster convergence. Furthermore, we showcase the potential of 3DGR-CT for real-time physical simulation, which holds important clinical applications while challenging for implicit neural representations. Code available at: https://github.com/SigmaLDC/3DGR-CT.

In this study, we explore using Stable Diffusion (SD) for unsupervised medical image-to-image translation. SD has shown remarkable performances in generating high-quality images and can be easily applied to generate custom contents by injecting standard plug-ins like LoRA, offering a promising solution to tackle the complexity caused by variations in imaging modalities, acquisition parameters, and body parts in medical imaging. However, We empirically find that existing pipelines designed for natural images fail to translate directly to medical images due to weak structural control and inappropriate color preservation. To address these issues, we propose a novel two-branch image translation pipeline. This pipeline decouples the generation of target image along the time axis and employs ControlNet to ensure precise structural preservation. Additionally, we customize SD to generate images of extreme brightness, a common feature in medical imaging. Our results on the BraTS dataset demonstrate that SD with task-specific plug-ins can generate high-quality medical images comparable to those generated by task-specific models. Since the development of these standard plug-ins can be easily done by clinicians without much knowledge of the underlying algorithm, such a mode holds the potential to significantly extend the use of medical image computing algorithms in the clinical environment.

Knowledge graph embedding maps entities and relations into low-dimensional vector space.However, it is still challenging for many existing methods to model diverse relational patterns, especially symmetric and antisymmetric relations.To address this issue, we propose a novel model, AprilE, which employs triple-level self-attention and pseudo residual connection to model relational patterns.The triple-level self-attention treats head entity, relation, and tail entity as a sequence and captures the dependency within a triple.At the same time the pseudo residual connection retains primitive semantic features.Furthermore, to deal with symmetric and antisymmetric relations, two schemas of score function are designed via a position-adaptive mechanism.Experimental results on public datasets demonstrate that our model can produce expressive knowledge embedding and significantly outperforms most of the state-of-the-art works.