Light field microscopy (LFM) has gained significant attention due to its ability to capture snapshot-based, large-scale 3D fluorescence images. However, existing LFM reconstruction algorithms are highly sensitive to sensor noise or require hard-to-get ground-truth annotated data for training. To address these challenges, this paper introduces V2V3D, an unsupervised view2view-based framework that establishes a new paradigm for joint optimization of image denoising and 3D reconstruction in a unified architecture. We assume that the LF images are derived from a consistent 3D signal, with the noise in each view being independent. This enables V2V3D to incorporate the principle of noise2noise for effective denoising. To enhance the recovery of high-frequency details, we propose a novel wave-optics-based feature alignment technique, which transforms the point spread function, used for forward propagation in wave optics, into convolution kernels specifically designed for feature alignment. Moreover, we introduce an LFM dataset containing LF images and their corresponding 3D intensity volumes. Extensive experiments demonstrate that our approach achieves high computational efficiency and outperforms the other state-of-the-art methods. These advancements position V2V3D as a promising solution for 3D imaging under challenging conditions. Our code and dataset will be publicly accessible at https://joey1998hub.github.io/V2V3D/.

Over the past few years, the YOLO series of models has emerged as one of the dominant methodologies in the realm of object detection. Many studies have advanced these baseline models by modifying their architectures, enhancing data quality, and developing new loss functions. However, current models still exhibit deficiencies in processing feature maps, such as overlooking the fusion of cross-scale features and a static fusion approach that lacks the capability for dynamic feature adjustment. To address these issues, this paper introduces an efficient Fine-grained Multi-scale Dynamic Selection Module (FMDS Module), which applies a more effective dynamic feature selection and fusion method on fine-grained multi-scale feature maps, significantly enhancing the detection accuracy of small, medium, and large-sized targets. Furthermore, this paper proposes an Adaptive Gated Multi-branch Focus Fusion Module (AGMF Module), which utilizes multiple parallel branches to perform complementary fusion of various features captured by the gated unit branch, FMDS Module branch, and TripletAttention branch. This approach further enhances the comprehensiveness, diversity, and integrity of feature fusion. This paper has integrated the FMDS Module, AGMF Module, into Yolov9 to develop a novel object detection model named FA-YOLO. Extensive experimental results show that under identical experimental conditions, FA-YOLO achieves an outstanding 66.1% mean Average Precision (mAP) on the PASCAL VOC 2007 dataset, representing 1.0% improvement over YOLOv9’s 65.1%. Additionally, the detection accuracies of FA-YOLO for small, medium, and large targets are 44.1%, 54.6%, and 70.8%, respectively, showing improvements of 2.0%, 3.1%, and 0.9% compared to YOLOv9’s 42.1%, 51.5%, and 69.9%.

3D Gaussian Splatting is widely used in 3D reconstruction and has applications in novel view synthesis and scene generation. Recent work has addressed this problem by leveraging multi-view data for high-quality 3D scene reconstruction. Unfortunately, these approaches suffer from overfitting with sparse-view data due to insufficient view information, resulting in artifacts and aliasing. In contrast, we propose a novel method, MPM-GS, which incorporates monocular depth estimation, virtual views, and regularization techniques to address these challenges and improve reconstruction quality under sparse-view conditions. This fixes the overfitting and artifact issues, however, it does not solve all the limitations of sparse-view data in extreme edge cases. Consequently, we develop a novel densification strategy to optimize Gaussian point distributions and improve scene accuracy. While promising, this densification process is non-trivial, as it requires balancing efficiency with rendering fidelity. Therefore, we further optimize Gaussian points and generate new, representative points to enhance both accuracy and computational efficiency. We evaluate MPM-GS both qualitatively and quantitatively on the Tanks & Temples and LLFF datasets, achieving excellent rendering quality and fast rendering speed, particularly in novel view synthesis.

Light field disparity estimation is an essential task in computer vision. Currently, supervised learning-based methods have achieved better performance than both unsupervised and optimization-based methods. However, the generalization capacity of supervised methods on real-world data, where no ground truth is available for training, remains limited. In this paper, we argue that unsupervised methods can achieve not only much stronger generalization capacity on real-world data but also more accurate disparity estimation results on synthetic datasets. To fulfill this goal, we present the Occlusion Pattern Aware Loss, named OPAL, which successfully extracts and encodes general occlusion patterns inherent in the light field for calculating the disparity loss. OPAL enables: i) accurate and robust disparity estimation by teaching the network how to handle occlusions effectively and ii) significantly reduced network parameters required for accurate and efficient estimation. We further propose an EPI transformer and a gradient-based refinement module for achieving more accurate and pixel-aligned disparity estimation results. Extensive experiments demonstrate our method not only significantly improves the accuracy compared with SOTA unsupervised methods, but also possesses stronger generalization capacity on real-world data compared with SOTA supervised methods. Last but not least, the network training and inference efficiency are much higher than existing learning-based methods. Our code will be made publicly available.