Recent advances in generalizable 3D Gaussian Splatting have demonstrated promising results in real-time high-fidelity rendering without per-scene optimization, yet existing approaches still struggle to handle unfamiliar visual content during inference on novel scenes due to limited generalizability. To address this challenge, we introduce MonoSplat, a novel framework that leverages rich visual priors from pre-trained monocular depth foundation models for robust Gaussian reconstruction. Our approach consists of two key components: a Mono-Multi Feature Adapter that transforms monocular features into multi-view representations, coupled with an Integrated Gaussian Prediction module that effectively fuses both feature types for precise Gaussian generation. Through the Adapter’s lightweight attention mechanism, features are seamlessly aligned and aggregated across views while preserving valuable monocular priors, enabling the Prediction module to generate Gaussian primitives with accurate geometry and appearance. Through extensive experiments on diverse real-world datasets, we convincingly demonstrate that MonoSplat achieves superior reconstruction quality and generalization capability compared to existing methods while maintaining computational efficiency with minimal trainable parameters. Codes are available at https://github.com/CUHK-AIM-Group/MonoSplat.

Automated diagnostic systems (ADS) have shown significant potential in the early detection of polyps during endoscopic examinations, thereby reducing the incidence of colorectal cancer. However, due to high annotation costs and strict privacy concerns, acquiring high-quality endoscopic images poses a considerable challenge in the development of ADS. Despite recent advancements in generating synthetic images for dataset expansion, existing endoscopic image generation algorithms failed to accurately generate the details of polyp boundary regions and typically required medical priors to specify plausible locations and shapes of polyps, which limited the realism and diversity of the generated images. To address these limitations, we present Polyp-Gen, the first full-automatic diffusion-based endoscopic image generation framework. Specifically, we devise a spatial-aware diffusion training scheme with a lesion-guided loss to enhance the structural context of polyp boundary regions. Moreover, to capture medical priors for the localization of potential polyp areas, we introduce a hierarchical retrieval-based sampling strategy to match similar fine-grained spatial features. In this way, our Polyp-Gen can generate realistic and diverse endoscopic images for building reliable ADS. Extensive experiments demonstrate the state-of-the-art generation quality, and the synthetic images can improve the downstream polyp detection task. Additionally, our Polyp-Gen has shown remarkable zeroshot generalizability on other datasets. The source code is available at https://github.com/CUHK-AIM-Group/Polyp-Gen.

Current image generation and editing methods primarily process textual prompts as direct inputs without explicit reasoning about visual composition or operational steps. We present Generation Chain-of-Thought (GoT), a novel paradigm that empowers a Multimodal Large Language Model (MLLM) to first generate an explicit, structured reasoning chain in natural language—detailing semantic relationships, object attributes, and, crucially, precise spatial coordinates—before any image synthesis occurs. This intermediate reasoning output directly guides the subsequent visual generation or editing process. This approach transforms conventional text-to-image generation and editing into a reasoning-guided framework that analyzes semantic relationships and spatial arrangements. We define the formulation of GoT and construct large-scale GoT datasets containing over \textbf{9M} samples with detailed reasoning chains capturing semantic-spatial relationships. To leverage the advantages of GoT, we implement a unified framework that integrates Qwen2.5-VL for reasoning chain generation with an end-to-end diffusion model enhanced by our novel Semantic-Spatial Guidance Module. Experiments show our GoT framework achieves excellent performance on both generation and editing tasks, with significant improvements over baselines. Additionally, our approach enables interactive visual generation, allowing users to explicitly modify reasoning steps for precise image adjustments. GoT pioneers a new direction for reasoning-driven visual generation and editing, producing images that better align with human intent. We will release our datasets and models to facilitate future research.