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Nicholas K. Akers

dblp:223/8352 · DBLP profile ↗
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1ranked-venue papers
1as first author
0since 2021 · last 2018
—ORCID · unresolved

Domains — the database's venue-derived domains; a paper can count in several

Applied, interdisciplinary, general and emerging computing · 1 · 1 first-author

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
1 paper
Bioinformatics and computational biology · 100%

Topics — the 3 heaviest of 3, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Bioinformatics and computational biology › transcriptomics › non-coding RNA analysis
circular RNA detection
0.312018
STAR Chimeric Post for rapid detection of circular RNA and fusion transcripts · Bioinform. 2018
Bioinformatics and computational biology › transcriptomics › RNA-seq analysis
fusion transcript detection
0.312018
STAR Chimeric Post for rapid detection of circular RNA and fusion transcripts · Bioinform. 2018
Bioinformatics and computational biology
transcriptomics
0.312018
STAR Chimeric Post for rapid detection of circular RNA and fusion transcripts · Bioinform. 2018

Methods — techniques the papers use, named apart from their topics

chimeric alignment processing · 0.3
YearPublicationVenuePosition
2018 STAR Chimeric Post for rapid detection of circular RNA and fusion transcripts
abstract
Motivation: The biological relevance of chimeric RNA alignments is now well established. Chimera arising as chromosomal fusions are often drivers of cancer and recently discovered circular RNA (circRNA) are only now being characterized. While software already exists for fusion discovery and quantitation, high false positive rates and high run-times hamper scalable fusion discovery on large datasets. Furthermore, software available for circRNA detection and quantification is limited. Results: Here, we present STAR Chimeric Post (STARChip), a novel software package that processes chimeric alignments from the STAR aligner and produces annotated circRNA and high precision fusions in a rapid, efficient and scalable manner that is appropriate for high dimensional medical omics datasets. Availability and implementation: STARChip is available at https://github.com/LosicLab/STARChip. Supplementary information: Supplementary data are available at Bioinformatics online.
Nicholas K. Akers, Eric E. Schadt, Bojan Losic
Bioinform.1