Collaborative exploration of scientific data sets across large high-resolution displays requires both high visual detail as well as low-latency transfer of image data (oftentimes inducing the need to trade one for the other). In this work, we present a system that dynamically adapts the encoding quality in such systems in a way that reduces the required bandwidth without impacting the details perceived by one or more observers. Humans perceive sharp, colourful details, in the small foveal region around the centre of the field of view, while information in the periphery is perceived blurred and colourless. We account for this by tracking the gaze of observers, and respectively adapting the quality parameter of each macroblock used by the H.264 encoder, considering the so-called visual acuity fall-off. This allows to substantially reduce the required bandwidth with barely noticeable changes in visual quality, which is crucial for collaborative analysis across display walls at different locations. We demonstrate the reduced overall required bandwidth and the high quality inside the foveated regions using particle rendering and parallel coordinates.

The advent of modern and affordable augmented reality head sets like Microsoft HoloLens has sparked new interest in using virtual and augmented reality technology in the analysis of molecular data. For all visualisation in immersive, mixed-reality scenarios, a sufficiently high rendering speed is an important factor, which leads to the issue of limited processing power available on fully untethered devices facing the situation of handling computationally expensive visualisations. Recent research shows that the space-filling model of even small data sets from the Protein Data Bank (PDB) cannot be rendered at desirable frame rates on the HoloLens. In this work, we report on how to improve the rendering speed of atom-based visualisation of proteins and how the rendering of more abstract representations of the molecules compares against it. We complement our findings with in-depth GPU and CPU performance numbers.

We present a technique that conveys the uncertainty in the secondary structure of proteins-an abstraction model based on atomic coordinates. While protein data inherently contains uncertainty due to the acquisition method or the simulation algorithm, we argue that it is also worth investigating uncertainty induced by analysis algorithms that precede visualization. Our technique helps researchers investigate differences between multiple secondary structure assignment methods. We modify established algorithms for fuzzy classification and introduce a discrepancy-based approach to project an ensemble of sequences to a single importance-weighted sequence. In 2D, we depict the aggregated secondary structure assignments based on the per-residue deviation in a collapsible sequence diagram. In 3D, we extend the ribbon diagram using visual variables such as transparency, wave form, frequency, or amplitude to facilitate qualitative analysis of uncertainty. We evaluated the effectiveness and acceptance of our technique through expert reviews using two example applications: the combined assignment against established algorithms and time-dependent structural changes originating from simulated protein dynamics.