Multi-objective molecular optimization is a fundamental yet inherently challenging task in drug discovery, as it requires simultaneously optimizing multiple, often conflicting, molecular properties. Although recent deep learning methods have shown promise, they often lack objective-specific specialization and dynamic coordination, making them ineffective in handling competing objectives and difficult to scale in complex, high-dimensional molecular design tasks. Inspired by the division of labor among domain experts in medicinal chemistry, we propose MAMO, a multi-agent framework for molecular design that simulates expert collaboration. Each agent specializes in optimizing a single objective, and their interactions are orchestrated by a central scheduling module that dynamically reallocates tasks based on evaluation feedback. This coordination mechanism enables interpretable and goal-conditioned optimization while adaptively balancing conflicting objectives. Extensive experiments on benchmark datasets demonstrate that MAMO consistently achieves superior performance in both objective quality and Pareto diversity, particularly in scenarios with strong inter-objective conflict. Our results highlight the potential of multi-agent coordination strategies for scalable and conflict-aware molecular design.

The convergence of unmanned aerial vehicle (UAV)-aided mobile edge computing (MEC) networks and blockchain transforms the existing mobile networking paradigm. However, in the temporary hotspot scenario for intelligent connected vehicles (ICVs) in UAV-aided MEC networks, deploying blockchain-based services and applications in vehicles is generally impossible due to its high computational resource and storage requirements. One possible solution is to offload part of all the computational tasks to MEC servers wherever possible. Unfortunately, due to the limited availability and high mobility of the vehicles, there is still lacking simple solutions that can support low-latency and higher reliability networking services for ICVs. In this article, we study the task offloading problem of minimizing the total system latency and the optimal task offloading scheme, subject to constraints on the hover position coordinates of the UAV, the fixed bonuses, flexible transaction fees, transaction rates, mining difficulty, costs and battery energy consumption of the UAV. The problem is confirmed to be a challenging linear integer planning problem, we formulate the problem as a constrained Markov decision process. Deep Reinforcement Learning (DRL) has excellently solved sequential decision-making problems in dynamic ICVs environment, therefore, we propose a novel distributed DRL-based P-D3QN approach by using Prioritized Experience Replay strategy and the dueling double deep Q-network (D3QN) algorithm to solve the optimal task offloading policy effectively. Finally, experiment results show that compared with the benchmark scheme, the P-D3QN algorithm can bring about 26.24% latency improvement and increase about 42.26% offloading utility.

The conventional approach to event extraction requires predefined event types and their corresponding annotations to train event extractors. However, these prerequisites are often difficult to satisfy in real-world applications. To automatically induct event types, most work has been devoted to clustering event triggers, where a cluster of event triggers is represented as an event type. Some works use trigger semantics, while others use co-occurrence relationships to cluster triggers. However, the clustering results of event triggers obtained by the above work are not sufficiently detailed in describing event types, making it difficult to accurately determine the corresponding event types manually. This paper proposes an open-domain event type induction framework that automatically discovers a set of event types from a given corpus. Unlike previous work on event trigger clustering, this paper takes into consideration the hierarchical relationship of event types to partition the event trigger clusters into event mains and subtypes. The framework employs a latent variable-based neural generation module and a semantic-based clustering module, the former of which obtains event trigger clusters representing the main types of events by jointly projecting the co-occurrence and semantic information of event triggers into a latent space for event type latent variable mining, and the latter of which further divides these event trigger clusters into event subtypes based on semantic information. Finally, experiment results show that, compared with the benchmark model, the ETGen-Clus can improve event type quality scores of 6.23% and 3.11% on the two datasets, respectively.