Reconstructing complete and interactive 3D scenes remains a fundamental challenge in computer vision and robotics, particularly due to persistent object occlusions and limited sensor coverage. Even multi-view observations from a single scene scan often fail to capture the full structural details. Existing approaches typically rely on multi-stage pipelines—such as segmentation, background completion, and inpainting—or require per-object dense scanning, both of which are error-prone, and not easily scalable. We propose IGFuse, a novel framework that reconstructs interactive Gaussian scene by fusing observations from multiple scans, where natural object rearrangement between captures reveal previously occluded regions. Our method constructs segmentation-aware Gaussian fields and enforces bi-directional photometric and semantic consistency across scans. To handle spatial misalignments, we introduce a pseudo-intermediate scene state for symmetric alignment, alongside collaborative co-pruning strategies to refine geometry. IGFuse enables high-fidelity rendering and object-level scene manipulation without dense observations or complex pipelines. Extensive experiments validate the framework’s strong generalization to novel scene configurations, demonstrating its effectiveness for real-world 3D reconstruction and real-to-simulation transfer.

How to resolve the metabolic dark matter of microorganisms has long been a challenging problem in discovering active molecules. Diverse omics tools have been developed to guide the discovery and characterization of various microbial metabolites, which make it gradually possible to predict the overall metabolites for individual strains. The combinations of multi-omic analysis tools effectively compensates for the shortcomings of current studies that focus only on single omics or a broad class of metabolites. In this review, we systematically update, categorize and sort out different analysis tools for microbial metabolites prediction in the last five years to appeal for the multi-omic combination on the understanding of the metabolic nature of microbes. First, we provide the general survey on different updated prediction databases, webservers, or software that based on genomics, transcriptomics, proteomics, and metabolomics, respectively. Then, we discuss the essentiality on the integration of multi-omics data to predict metabolites of different microbial strains and communities, as well as stressing the combination of other techniques, such as systems biology methods and data-driven algorithms. Finally, we identify key challenges and trends in developing multi-omic analysis tools for more comprehensive prediction on diverse microbial metabolites that contribute to human health and disease treatment.

Endotracheal intubation is a mandatory competency for most medical staff. This procedure involves opening the entrance of the patient's upper windpipe using a laryngoscope and then inserting a tube into the windpipe to supply Oxygen to the patient. This time critical intervention requires careful control of the force vector on the tongue to lift it parallel to the jaw than to push the jaw to open the mouth. However, traditional intubation training methods in which novices practice intubation on prostheses lack haptic feedback to improve force control. We designed a sensorised intubation training phantom that can provide trainees with vibrotactile feedback reflecting the laryngoscope's force on the tongue. The critical component of this phantom is a silicon rubber tongue embedded with magnets and hall effect sensors. We calibrated the hall effect sensor readings to predict the force vector exerted on the tongue with errors less than 0.5 N in the lifting and pushing directions. We conducted a controlled experiment, mainly comparing the training results between participants with and without haptic feedback. Results show a statistically significant drop in the undesired forces due to haptic feedback, and the skill is retained when tested after 24 hours without haptic feedback.