The recent revolutionary progress in text-based large language models (LLMs) has contributed to the growth of interest in extending capabilities of such models to multimodal perception and understanding tasks. Hearing is an essential capability that is highly desired to be integrated into LLMs. However, effective integrating listening capabilities into LLMs is a significant challenge lying in generalizing complex auditory tasks across speech and sounds. To address these issues, we introduce Cryfish, our version of auditory-capable LLM. The model integrates WavLM audio-encoder features into Qwen2 model using a transformer-based connector. Cryfish is adapted to various auditory tasks through a specialized training strategy. We evaluate the model on the new Dynamic SUPERB Phase-2 comprehensive multitask benchmark specifically designed for auditory-capable models. The paper presents an in-depth analysis and detailed comparison of Cryfish with the publicly available models.

Co-crystallization is an accessible way to control physicochemical characteristics of organic crystals, which finds many biomedical applications. In this work, we present Generative Method for Co-crystal Design (GEMCODE), a novel pipeline for automated co-crystal screening based on the hybridization of deep generative models and evolutionary optimization for broader exploration of the target chemical space. GEMCODE enables fast *de novo* co-crystal design with target tabletability profiles, which is crucial for the development of pharmaceuticals. With a series of experimental studies highlighting validation and discovery cases, we show that GEMCODE is effective even under realistic computational constraints. Furthermore, we explore the potential of language models in generating co-crystals. Finally, we present numerous previously unknown co-crystals predicted by GEMCODE and discuss its potential in accelerating drug development.