In this work we propose a new scheme for semi-active Wake-Up Receiver circuits that exhibits remarkable sensitivity beyond -70 dBm, while state-of-the-art receivers illustrate sensitivity of up to -55 dBm. The receiver employs the typical principle of an envelope detector that harvests RF energy from its antenna, while it employs a nano-power operation amplifier to intensify the obtained signal prior to the final decoding that is realized with the aid of a comparator circuit. It operates at the 868 MHz ISM band using OOK signals propagated through LoRa transceivers, while also supporting addressing capabilities in order to awake only the specified network's nodes. The power expenditure of the developed receiver is as low as 580 nA, remaining at the same power consumption levels as the state-of-the-art implementations.