This paper proposes a novel neural network architecture RBF-KAN, integrating the theoretical robustness of Kolmogorov-Arnold Networks (KANs) with the localized features of Radial Basis Function (RBF) networks. To address the low computational efficiency and poor interpretability of original KANs caused by B-spline basis functions, RBF-KAN adopts RBF as the core function for activation parameterization, while retaining KAN’s theoretical guarantees. Experiments on function approximation, basic classification datasets (Moon, Concentric circles, etc.), and the real-world large-scale Adult dataset demonstrate that RBF-KAN achieves competitive accuracy with significantly enhanced efficiency compared to KAN and FourierKAN. Specifically, it reduces parameters by 33%–65% and accelerates inference/training by 65%–99% while maintaining comparable accuracy (e.g., 0.8357 vs. KAN’s 0.8157 on Adult dataset). It exhibits excellent stability and generalization, especially in high-dimensional and large-scale scenarios. This work highlights RBF-KAN’s strengths, limitations, and future directions, underscoring its potential in tackling complex function approximation and classification challenges.

Massive multiple-input multiple-output (MIMO) systems employing one-bit digital-to-analog converters offer a hardware-efficient solution for wireless communications. However, the one-bit constraint poses significant challenges for precoding design, as it transforms the problem into a discrete and nonconvex optimization task. In this paper, we investigate a widely adopted ``convex-relaxation-then-quantization" approach for nonlinear symbol-level one-bit precoding. Specifically, we first solve a convex relaxation of the discrete minimum mean square error precoding problem, and then quantize the solution to satisfy the one-bit constraint. Focusing on a real-valued system with an independently and identically distributed (i.i.d.) Gaussian channel, we develop a novel analytical framework based on approximate message passing (AMP) to characterize the high-dimensional asymptotic performance of the considered scheme. The key technical ingredient is an auxiliary AMP iteration that dedicatedly incorporates the nonlinear quantization function into the state evolution analysis. With the proposed framework, we derive a closed-form expression for the symbol error probability (SEP) at the receiver side in the large-system limit, which provides a quantitative characterization of how model and system parameters affect the SEP performance. Our empirical results suggest that the $\ell_\infty^2$ regularizer, when paired with an optimally chosen regularization parameter, achieves optimal SEP performance within a broad class of convex regularization functions. As a first step towards a theoretical justification, we prove the optimality of the $\ell_\infty^2$ regularizer within the mixed $\ell_\infty^2$-$\ell_2^2$ regularization functions.

Beyond diagonal reconfigurable intelligent surface (BD-RIS) has emerged as an advancement and generalization of the conventional diagonal RIS (D-RIS) by introducing tunable interconnections between RIS elements, enabling smarter wave manipulation and enlarged coverage. While BD-RIS has demonstrated advantages over D-RIS in various aspects, most existing works rely on the assumption of a lossless model, leaving practical considerations unaddressed. This paper thus proposes a lossy BD-RIS model and develops corresponding optimization algorithms for various BD-RIS-aided communication systems. First, by leveraging admittance parameter analysis, we model each tunable admittance component based on a lumped circuit with losses and derive an expression of a circle characterizing the real and imaginary parts of each tunable admittance. We then consider the received signal power maximization in single-user single-input single-output (SISO) systems with the proposed lossy BD-RIS model. To solve the formulated challenging optimization problem, we design an effective algorithm by carefully exploiting the problem structure. In particular, an alternating direction method of multipliers (ADMM) framework is custom-designed to deal with the complicated constraints associated with lossy BD-RIS. Furthermore, we extend the proposed algorithmic framework to more general multiuser multiple-input single-output (MU-MISO) systems, where the transmit precoder and BD-RIS scattering matrix are jointly designed to maximize the sum-rate of the system. Finally, simulation results demonstrate that all BD-RIS architectures still outperform D-RIS in the presence of losses, but the optimal BD-RIS architectures in the lossless case are not necessarily optimal in the lossy case, e.g. group-connected BD-RIS can outperform fully- and tree-connected BD-RISs in SISO systems with relatively high losses at BD-RIS, whereas the opposite always holds true in the lossless case.

Reconfigurable intelligent surface (RIS) is a promising technology for future wireless communication systems. Conventional RIS is constrained to a diagonal scattering matrix, which limits its flexibility. Recently, beyond-diagonal RIS (BD-RIS) has been proposed as a more general RIS architecture class that allows inter-element connections and shows great potential for performance improvement. Despite extensive progress on BD-RIS, most existing studies rely on simplified channel models that ignore practical electromagnetic (EM) effects such as mutual coupling and impedance mismatching. To address this gap, this paper investigates the architecture design and optimization of BD-RIS under the general physics-consistent model derived with multiport network theory in recent literature. Building on a compact reformulation of this model, we show that band-connected RIS achieves the same channel-shaping capability as fully-connected RIS, which extends existing results obtained for conventional channel models. We then develop optimization methods under the general physics-consistent model; specifically, we derive closed-form solutions for single-input single-output (SISO) systems, propose a globally optimal semidefinite relaxation (SDR)–based algorithm for single-stream multi-input multi-output (MIMO) systems, and design an efficient alternating direction method of multipliers (ADMM)–based algorithm for multiuser MIMO systems. Using the proposed algorithms, we conduct comprehensive simulations to evaluate the impact of various EM effects and approximations. The results indicate that the commonly adopted unilateral approximation provides sufficient accuracy in RIS-aided systems and can therefore be readily adopted to simplify the channel model, whereas mutual coupling among RIS elements should be properly taken into account in channel modeling.

Single-cell RNA sequencing (scRNA-seq) technology has opened new frontiers in biomedical research, offering insights into cellular heterogeneity. Accurate cell clustering and batch effect correction are essential in single-cell RNA sequencing (scRNA-seq) data analysis, forming the foundation for downstream steps. However, most methods handle these tasks separately, limiting their applicability across diverse datasets. To address these challenges, we introduce Relational Graph Convolutional Network with Batch Awareness (RGCN-BA), a deep learning framework that integrates cell clustering and batch effect correction into a unified model. For multi-batch datasets, RGCN-BA leverages relational graph convolutional network to process batch information as distinct edge types, followed by a batch correction layer for global alignment. For single-batch data, it functions with a single edge type. Experiments on both multi-batch and single-batch datasets demonstrate that RGCN-BA outperforms both specialized clustering methods and batch effect correction methods. This versatility in handling both tasks positions RGCN-BA as a powerful tool for enhancing scRNA-seq data analysis.

Both dual-functional radar-communication (DFRC) and massive multiple-input multiple-output (MIMO) have been recognized as enabling technologies for 6G wireless networks. This paper considers the advanced waveform design for hardware-efficient massive MIMO DFRC systems. Specifically, the transmit waveform is imposed with the quantized constant-envelope (QCE) constraint, which facilitates the employment of low-resolution digital-to-analog converters (DACs) and power-efficient amplifiers. The waveform design problem is formulated as the minimization of the mean square error (MSE) between the designed and desired beampatterns subject to the constructive interference (CI)-based communication quality of service (QoS) constraints and the QCE constraint. To solve the formulated problem, we first utilize the penalty technique to transform the discrete problem into an equivalent continuous penalty model. Then, we propose an inexact augmented Lagrangian method (ALM) algorithm for solving the penalty model. In particular, the ALM subproblem at each iteration is solved by a custom-built block successive upper-bound minimization (BSUM) algorithm, which admits closed-form updates, making the proposed inexact ALM algorithm computationally efficient. Simulation results demonstrate the superiority of the proposed approach over existing state-of-the-art ones. In addition, extensive simulations are conducted to examine the impact of various system parameters on the trade-off between communication and radar performances.

Mathematical optimization is now widely regarded as an indispensable modeling and solution tool for the design of wireless communications systems. While optimization has played a significant role in the revolutionary progress in wireless communication and networking technologies from 1G to 5G and onto the future 6G, the innovations in wireless technologies have also substantially transformed the nature of the underlying mathematical optimization problems upon which the system designs are based and have sparked significant innovations in the development of methodologies to understand, to analyze, and to solve those problems. In this paper, we provide a comprehensive survey of recent advances in mathematical optimization theory and algorithms for wireless communication system design. We begin by illustrating common features of mathematical optimization problems arising in wireless communication system design. We discuss various scenarios and use cases and their associated mathematical structures from an optimization perspective. We then provide an overview of recently developed optimization techniques in areas ranging from nonconvex optimization, global optimization, and integer programming, to distributed optimization and learning-based optimization. The key to successful solution of mathematical optimization problems is in carefully choosing or developing suitable algorithms (or neural network architectures) that can exploit the underlying problem structure. We conclude the paper by identifying several open research challenges and outlining future research directions.

Intelligent reflecting surface (IRS) is an emerging technology to enhance spatial multiplexing in wireless networks. This letter considers the discrete passive beamforming design for IRS in order to maximize the minimum signal-to-interference-plus-noise ratio (SINR) among multiple users in an IRS-assisted downlink network. The main design difficulty lies in the discrete phase-shift constraint. Differing from most existing works, this letter advocates a convex-hull relaxation of the discrete constraints which leads to a continuous reformulated problem equivalent to the original discrete problem. This letter further proposes an efficient alternating projection/proximal gradient descent and ascent algorithm for solving the reformulated problem. Simulation results show that the proposed algorithm outperforms the state-of-the-art methods significantly.

A promising approach to deal with the high hardware cost and energy consumption of massive MIMO transmitters is to use low-resolution digital-to-analog converters (DACs) at each antenna element. This leads to a transmission scheme where the transmitted signals are restricted to a finite set of voltage levels. This paper is concerned with the analysis and optimization of a low-cost quantized precoding strategy, referred to as linear-quantized precoding, for a downlink massive MIMO system under Rayleigh fading. In linear-quantized precoding, the signals are first processed by a linear precoding matrix and subsequently quantized component-wise by the DAC. In this paper, we analyze both the signal-to-interference-plus-noise ratio (SINR) and the symbol error probability (SEP) performances of such linear-quantized precoding schemes in an asymptotic framework where the number of transmit antennas and the number of users grow large with a fixed ratio. Our results provide a rigorous justification for the heuristic arguments based on the Bussgang decomposition that are commonly used in prior works. Based on the asymptotic analysis, we further derive the optimal precoder within a class of linear-quantized precoders that includes several popular precoders as special cases. Our numerical results demonstrate the excellent accuracy of the asymptotic analysis for finite systems and the optimality of the derived precoder.

In this paper, we consider the one-bit precoding problem for the multiuser downlink massive multiple-input multiple-output (MIMO) system with phase shift keying (PSK) modulation. We focus on the celebrated constructive interference (CI)-based problem formulation. We first establish the NP-hardness of the problem (even in the single-user case), which reveals the intrinsic difficulty of globally solving the problem. Then, we propose a novel negative ℓ1penalty model for the considered problem, which penalizes the one-bit constraint into the objective by a negative ℓ1-norm term, and show the equivalence between (global and local) solutions of the original problem and the penalty problem when the penalty parameter is sufficiently large. We further transform the penalty model into an equivalent min-max problem and propose an efficient alternating proximal/projection gradient descent ascent (APGDA) algorithm for solving it, which performs a proximal gradient decent over one block of variables and a projection gradient ascent over the other block of variables alternately. The APGDA algorithm enjoys a low per-iteration complexity and is guaranteed to converge to a stationary point of the min-max problem and a local minimizer of the penalty problem. To further reduce the computational cost, we also propose a low-complexity implementation of the APGDA algorithm, where the values of the variables will be fixed in later iterations once they satisfy the one-bit constraint. Numerical results show that, compared to the state-of-the-art CI-based algorithms, both of the proposed algorithms generally achieve better bit-error-rate (BER) performance with lower computational cost.

Quantized constant envelope (QCE) precoding, a new transmission scheme that only discrete QCE transmit signals are allowed at each antenna, has gained growing research interests due to its ability of reducing the hardware cost and the energy consumption of massive multiple-input multiple-output (MIMO) systems. However, the discrete nature of QCE transmit signals greatly complicates the precoding design. In this paper, we consider the QCE precoding problem for a massive MIMO system with phase shift keying (PSK) modulation and develop an efficient approach for solving the constructive interference (CI) based problem formulation. Our approach is based on a custom-designed (continuous) penalty model that is equivalent to the original discrete problem. Specifically, the penalty model relaxes the discrete QCE constraint and penalizes it in the objective with a negative ℓ2-norm term, which leads to a non-smooth nonconvex optimization problem. To tackle it, we resort to our recently proposed alternating optimization (AO) algorithm. We show that the AO algorithm admits closed-form updates at each iteration when applied to our problem and thus can be efficiently implemented. Simulation results demonstrate the superiority of the proposed approach over the existing algorithms.

MOTIVATION: An imperative step in drug discovery is the prediction of drug-disease associations (DDAs), which tries to uncover potential therapeutic possibilities for already validated drugs. It is costly and time-consuming to predict DDAs using wet experiments. Graph Neural Networks as an emerging technique have shown superior capacity of dealing with DDA prediction. However, existing Graph Neural Networks-based DDA prediction methods suffer from sparse supervised signals. As graph contrastive learning has shined in mitigating sparse supervised signals, we seek to leverage graph contrastive learning to enhance the prediction of DDAs. Unfortunately, most conventional graph contrastive learning-based models corrupt the raw data graph to augment data, which are unsuitable for DDA prediction. Meanwhile, these methods could not model the interactions between nodes effectively, thereby reducing the accuracy of association predictions. RESULTS: A model is proposed to tap potential drug candidates for diseases, which is called Similarity Measures-based Graph Co-contrastive Learning (SMGCL). For learning embeddings from complicated network topologies, SMGCL includes three essential processes: (i) constructs three views based on similarities between drugs and diseases and DDA information; (ii) two graph encoders are performed over the three views, so as to model both local and global topologies simultaneously; and (iii) a graph co-contrastive learning method is introduced, which co-trains the representations of nodes to maximize the agreement between them, thus generating high-quality prediction results. Contrastive learning serves as an auxiliary task for improving DDA predictions. Evaluated by cross-validations, SMGCL achieves pleasing comprehensive performances. Further proof of the SMGCL's practicality is provided by case study of Alzheimer's disease. AVAILABILITY AND IMPLEMENTATION: https://github.com/Jcmorz/SMGCL.

This paper considers the one-bit precoding problem for the multiuser downlink massive multiple-input multiple-output (MIMO) system with phase shift keying (PSK) modulation and focuses on the celebrated constructive interference (CI)-based problem formulation. The existence of the discrete one-bit constraint makes the problem generally hard to solve. In this paper, we propose an efficient negative ℓ1penalty approach for finding a high-quality solution of the considered problem. Specifically, we first propose a novel negative ℓ1penalty model, which penalizes the one-bit constraint into the objective with a negative ℓ1-norm term, and show the equivalence between (global and local) solutions of the original problem and the penalty problem when the penalty parameter is sufficiently large. We further transform the penalty model into an equivalent min-max problem and propose an efficient alternating optimization (AO) algorithm for solving it. The AO algorithm enjoys low periteration complexity and is guaranteed to converge to the stationary point of the min-max problem. Numerical results show that, compared against the state-of-the-art CI-based algorithms, the proposed algorithm generally achieves better bit-error-rate (BER) performance with lower computational cost.