Self-supervised learning has shown great promise in leveraging large amounts of unlabeled data to achieve higher accuracy than supervised learning methods in many domains. Generative self-supervised learning can generate new data based on the trained data distribution. In this paper, we evaluate the effectiveness of generative self-supervised learning on combinational gate sizing in VLSI designs. We propose a novel use of Transformers for gate sizing when trained on a large dataset generate from a commercial EDA tool. We demonstrate that our trained model can achieve 93% accuracy, 1440X speedup and fast design convergence when compared to a leading commercial EDA tool.

Gate sizing is a fundamental netlist optimization move and researchers have used supervised learning-based models in gate sizers. Recently, Reinforcement Learning (RL) has been tried for sizing gates (and other EDA optimization problems) but are very runtime-intensive. In this work, we explore a novel Transformer-based gate sizer, TransSizer, to directly generate optimized gate sizes given a placed and unoptimized netlist. TransSizer is trained on datasets obtained from real tapeout-quality industrial designs in a foundry 5nm technology node. Our results indicate that TransSizer achieves 97% accuracy in predicting optimized gate sizes at the postroute optimization stage. Furthermore, TransSizer has a speedup of ~1400× while delivering similar timing, power and area metrics when compared to a leading-edge commercial tool for sizing-only optimization.

Generalized nucleus segmentation techniques can contribute greatly to reducing the time to develop and validate visual biomarkers for new digital pathology datasets. We summarize the results of MoNuSeg 2018 Challenge whose objective was to develop generalizable nuclei segmentation techniques in digital pathology. The challenge was an official satellite event of the MICCAI 2018 conference in which 32 teams with more than 80 participants from geographically diverse institutes participated. Contestants were given a training set with 30 images from seven organs with annotations of 21,623 individual nuclei. A test dataset with 14 images taken from seven organs, including two organs that did not appear in the training set was released without annotations. Entries were evaluated based on average aggregated Jaccard index (AJI) on the test set to prioritize accurate instance segmentation as opposed to mere semantic segmentation. More than half the teams that completed the challenge outperformed a previous baseline. Among the trends observed that contributed to increased accuracy were the use of color normalization as well as heavy data augmentation. Additionally, fully convolutional networks inspired by variants of U-Net, FCN, and Mask-RCNN were popularly used, typically based on ResNet or VGG base architectures. Watershed segmentation on predicted semantic segmentation maps was a popular post-processing strategy. Several of the top techniques compared favorably to an individual human annotator and can be used with confidence for nuclear morphometrics.