The Metabolic Transformation Algorithm (MTA) leverages constraint-based modeling to identify metabolic interventions capable of shifting a biological system from an undesired to a desired state. Its robust extension (rMTA) strengthens predictive accuracy through worst-case scenario analyses and the integration of Minimization Of Metabolic Adjustment (MOMA) algorithm.

The rapid advancement of energy-efficient parallel ultra-low-power (ULP)$\mu$controllers units (MCUs) is enabling the development of autonomous nano-sized unmanned aerial vehicles (nano-UAVs). These sub-10cm drones represent the next generation of unobtrusive robotic helpers and ubiquitous smart sensors. However, nano-UAVs face significant power and payload constraints while requiring advanced computing capabilities akin to standard drones, including real-time Machine Learning (ML) performance and the safe co-existence of general-purpose and real-time OSs. Although some advanced parallel ULP MCUs offer the necessary ML computing capabilities within the prescribed power limits, they rely on small main memories ($<$1MB) and$\mu$controller-class CPUs with no virtualization or security features, and hence only support simple bare-metal runtimes. In this work, we present Shaheen, a 9mm$^{\textbf{2}}$200mW SoC implemented in 22nm FDX technology. Differently from state-of-the-art MCUs, Shaheen integrates a Linux-capable RV64 core, compliant with the v1.0 ratified Hypervisor extension and equipped with timing channel protection, along with a low-cost and low-power memory controller exposing up to 512MB of off-chip low-cost low-power HyperRAM directly to the CPU. At the same time, it integrates a fully programmable energy-and area-efficient multi-core cluster of RV32 cores optimized for general-purpose DSP as well as reduced-and mixed-precision ML. To the best of the authors’ knowledge, it is the first silicon prototype of a ULP SoC coupling the RV64 and RV32 cores in a heterogeneous host+accelerator architecture fully based on the RISC-V ISA. We demonstrate the capabilities of the proposed SoC on a wide range of benchmarks relevant to nano-UAV applications including general-purpose DSP as well as inference and online learning of quantized DNNs. The cluster can deliver up to 90GOp/s and up to 1.8TOp/s/W on 2-bit integer kernels and up to 7.9GFLOp/s and up to 150GFLOp/s/W on 16-bit FP kernels.

This work describes our efforts to provide a holistic hardware RISC-V virtualization SoC based on the CVA6 core. At the core level, we implemented hardware support for virtualization through the ratified Hypervisor instruction set architecture (ISA) extension version 1.0. At the system level, we are working on providing reference open-source IPs for two non-ISA components needed to build a virtualization-aware platform: (i) the advanced interrupt architecture (AIA) to enable hardware support for interrupt virtualization; (ii) the input/output memory management unit (IOMMU) to protect memory accesses from direct memory access (DMA) devices. All these IPs will be open and freely available to the RISC-V community under permissive open-source licenses.

Open Source Hardware, the way it should be!

Virtualization is a key technology used in a wide range of applications, from cloud computing to embedded systems. Over the last few years, mainstream computer architectures were extended with hardware virtualization support, giving rise to a set of virtualization technologies (e.g., Intel VT and Arm VE) that are now proliferating in modern processors and systems on chip (SoCs). In this article, we describe our work on hardware virtualization support in the RISC-V CVA6 core. Our contribution is multifold and encompasses architecture, microarchitecture, and design space exploration (DSE). In particular, we highlight the design of a set of microarchitectural enhancements [i.e., G-stage translation lookaside buffer (GTLB) and second-level TLB (L2 TLB)] to alleviate the virtualization performance overhead. We also perform a DSE and accompanying postlayout simulations (based on 22-nm FDX technology) to assess performance, power, and area (PPA). Furthermore, we map design variants on a field-programmable gate array (FPGA) platform (Genesys 2) to assess the functional performance–area tradeoff. Based on the DSE, we select an optimal design point for the CVA6 with hardware virtualization support. For this optimal hardware configuration, we collected functional performance results by running the MiBench benchmark on Linux atop Bao hypervisor for a single-core configuration. We observed a performance speedup of up to 16% (approximately 12.5% on average) compared with virtualization-aware nonoptimized design at the minimal cost of 0.78% in area and 0.33% in power. Finally, all works described in this article are publicly available and open-sourced for the community to further evaluate additional design configurations and software stacks.

This article describes the first public implementation and evaluation of the latest version of the RISC-V hypervisor extension (H-extension v0.6.1) specification in a Rocket chip core. To perform a meaningful evaluation for modern multi-core embedded and mixed-criticality systems, we have ported Bao, an open-source static partitioning hypervisor, to RISC-V. We have also extended the RISC-V platform-level interrupt controller (PLIC) to enable direct guest interrupt injection with low and deterministic latency and we have enhanced the timer infrastructure to avoid trap and emulation overheads. Experiments were carried out in FireSim, a cycle-accurate, FPGA-accelerated simulator, and the system was also successfully deployed and tested in a Zynq UltraScale+ MPSoC ZCU104. Our hardware implementation was open-sourced and is currently in use by the RISC-V community towards the ratification of the H-extension specification.