Dental care is important to pupils in elementary school since it affects their physical and mental development significantly. Therefore, dental care education is an important issue for governments around the world. Based on this, this study proposed a computer vision interactive game for supporting dental care education in Taiwan. Different from traditional lecture-based instruction, this study developed an interactive educational game that applied artificial intelligence technology to develop a computer vision service for recognizing pupils' dental photos and thus engaged pupils in playing an interactive game to prevent caries. To evaluate the proposed approach, an experiment was conducted in an elementary school and twenty-one fifth grade students was asked to participant in the experiment. The results indicated that the proposed approach can improve students' learning motivation, learning attitude, and learning achievement.