Large Language Models (LLMs) are revolutionizing how users interact with information systems, yet their high inference cost poses serious scalability and sustainability challenges. Caching inference responses, allowing them to be retrieved without another forward pass through the LLM, has emerged as one possible solution. Traditional exact-match caching, however, overlooks the semantic similarity between queries, leading to unnecessary recomputation. Semantic caching addresses this by retrieving responses based on semantic similarity, but introduces a fundamentally different cache eviction problem: one must account for mismatch costs between incoming queries and cached responses. Moreover, key system parameters, such as query arrival probabilities and serving costs, are often unknown and must be learned over time. Existing semantic caching methods are largely ad-hoc, lacking theoretical foundations and unable to adapt to real-world uncertainty. In this paper, we present a principled, learning-based framework for semantic cache eviction under unknown query and cost distributions. We formulate both offline optimization and online learning variants of the problem, and develop provably efficient algorithms with state-of-the-art guarantees. We also evaluate our framework on a synthetic dataset, showing that our proposed algorithms perform matching or superior performance compared with baselines.

We consider the contextual combinatorial bandit setting where in each round, the learning agent, e.g., a recommender system, selects a subset of "arms,'' e.g., products, and observes rewards for both the individual base arms, which are a function of known features (called "context''), and the super arm (the subset of arms), which is a function of the base arm rewards. The agent's goal is to simultaneously learn the unknown reward functions and choose the highest-reward arms. For example, the "reward'' may represent a user's probability of clicking on one of the recommended products. Conventional bandit models, however, employ restrictive reward function models in order to obtain performance guarantees. We make use of deep neural networks to estimate and learn the unknown reward functions and propose Neural UCB Clustering (NeUClust), which adopts a clustering approach to select the super arm in every round by exploiting underlying structure in the context space. Unlike prior neural bandit works, NeUClust uses a neural network to estimate the super arm reward and select the super arm, thus eliminating the need for a known optimization oracle. We non-trivially extend prior neural combinatorial bandit works to prove that NeUClust achieves sublinear regret in the number of rounds. Experiments on real world recommendation datasets show that NeUClust achieves better regret and reward than other contextual combinatorial and neural bandit algorithms.