The teacher-student paradigm has emerged as a canonical framework in semi-supervised learning. When applied to medical image segmentation, the paradigm faces challenges due to inherent image ambiguities, making it particularly vulnerable to erroneous supervision. Crucially, the student's iterative reconfirmation of these errors leads to self-reinforcing bias. While some studies attempt to mitigate this bias, they often rely on external modifications to the conventional teacher-student framework, overlooking its intrinsic potential for error correction. In response, this work introduces a feedback mechanism into the teacher-student framework to counteract error reconfirmations. Here, the student provides feedback on the changes induced by the teacher's pseudo-labels, enabling the teacher to refine these labels accordingly. We specify that this interaction hinges on two key components: the feedback attributor, which designates pseudo-labels triggering the student's update, and the feedback receiver, which determines where to apply this feedback. Building on this, a dual-teacher feedback model is further proposed, which allows more dynamics in the feedback loop and fosters more gains by resolving disagreements through cross-teacher supervision while avoiding consistent errors. Comprehensive evaluations on three medical image benchmarks demonstrate the method's effectiveness in addressing error propagation in semi-supervised medical image segmentation.

Fetal MRI is often acquired with thick slices to mitigate motion artifacts, but this leads to partial volume effects and reduced through-plane spatial resolution, limiting precise anatomical analysis. To address this, various super-resolution methods have been proposed to reconstruct high-resolution volumes from thick-slice scans. Current methods face several major challenges: 1) relying on multi-stack paired data makes arbitrary super-resolution ratios difficult to achieve; 2) lacking robustness against voxel coordinate misalignment caused by partial volume effects; 3) failing to fully utilize the high in-plane resolution of MRI images. To address these issues, we propose a dual-consistency guided curriculum learning method based on implicit neural representation, which uses single-stack inputs to achieve arbitrary super-resolution. We introduce progressive consistency and volumetric consistency to mitigate voxel misalignment caused by partial volume effects and ensure smooth transitions during the model's curriculum-based training. Additionally, we design a curriculum-aware multi-scale feature interaction block to fully leverage thick-slice MRI's high in-plane resolution. Comprehensive evaluations on three fetal MRI datasets demonstrate SOTA performance, with particularly outstanding results in high-ratio super-resolution tasks.

Radiographic attributes of lung nodules remedy the shortcomings of lung cancer computer-assisted diagnosis systems, which provides interpretable diagnostic reference for doctors. However, current studies fail to dedicate multi-label classification of lung nodules using convolutional neural networks (CNNs) and are inferior in exploiting statistical dependency between the labels. In addition, data imbalance is an indispensable problem to be reckoned with when employing CNNs to perform lung nodule classification. It introduces greater challenges especially in the multi-label classification. In this paper, we propose a method called MLSL-Net to discriminate lung nodule characteristics and simultaneously address the challenges. Particularly, the proposal employs multi-label softmax loss (MLSL) as the performance index, aiming to reduce the ranking errors between the labels and within the labels during training, thereby optimizing ranking loss and AUC directly. Such criterions can better evaluate the classifier's performance on the multi-label imbalanced dataset. Furthermore, a scale factor is introduced based on the investigation of the max surrogate function. Different from preceding usages, the small factor is used so that to narrow the discrepancy of gradients produced by different labels. More interestingly, this factor also facilitates the exploit of label dependency. Experimental results on the LIDC-IDRI dataset as well as another akin dataset demonstrate that MLSL-Net can effectively perform multi-label classification despite the imbalance issue. Meanwhile, the results confirm the responsibility of the factor for capturing label correlations, accordingly leading to more accurate predictions.