Small object detection (SOD) in anti-UAV task is a challenging problem due to the small size of UAVs and complex backgrounds. Traditional frame-based cameras struggle to detect small objects in complex environments due to their low frame rates, limited dynamic range, and data redundancy. Event cameras, with microsecond temporal resolution and high dynamic range, provide a more effective solution for SOD. However, existing event-based object detection datasets are limited in scale, feature large targets size, and lack diverse backgrounds, making them unsuitable for SOD benchmarks. In this paper, we introduce a Event-based Small object detection (EVSOD) dataset (namely EV-UAV), the first large-scale, highly diverse benchmark for anti-UAV tasks. It includes 147 sequences with over 2.3 million event-level annotations, featuring extremely small targets (averaging 6.8 $\times$ 5.4 pixels) and diverse scenarios such as urban clutter and extreme lighting conditions. Furthermore, based on the observation that small moving targets form continuous curves in spatiotemporal event point clouds, we propose Event based Sparse Segmentation Network (EV-SpSegNet), a novel baseline for event segmentation in point cloud space, along with a Spatiotemporal Correlation (STC) loss that leverages motion continuity to guide the network in retaining target events. Extensive experiments on the EV-UAV dataset demonstrate the superiority of our method and provide a benchmark for future research in EVSOD. The dataset and code are at https://github.com/ChenYichen9527/Ev-UAV.

Mass spectrometry (MS)-based proteomics has become instrumental in comprehensively investigating complex biological systems. Data-independent acquisition (DIA)-MS, utilizing hybrid spectral library search strategies, allows for the simultaneous quantification of thousands of proteins, showing promise in enhancing protein identification and quantification precision. However, low-quality profiles can considerably undermine quantitative precision, resulting in inaccurate protein quantification. To tackle this challenge, we introduced STAVER, a novel algorithm that leverages standardized benchmark datasets to reduce non-biological variation in large-scale DIA-MS analyses. By eliminating unwanted noise in MS signals, STAVER significantly improved protein quantification precision, especially in hybrid spectral library searches. Moreover, we validated STAVER's robustness and applicability across multiple large-scale DIA datasets, demonstrating significantly enhanced precision and reproducibility of protein quantification. STAVER offers an innovative and effective approach for enhancing the quality of large-scale DIA proteomic data, facilitating cross-platform and cross-laboratory comparative analyses. This advancement significantly enhances the consistency and reliability of findings in clinical research. The complete package is available at https://github.com/Ran485/STAVER.