Demo Data from EDBT 2026 / reviewers in the wild / expert
Zhaoduo Zhang
dblp:35/631
· DBLP profile ↗
1ranked-venue papers
0as first author
0since 2021 · last 2007
—ORCID · none
Domains — the database's venue-derived domains; a paper can count in several
Applied, interdisciplinary, general and emerging computing · 1
Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.
| Interdisciplinary, comprehensive, and emerging computing
1 paper |
Bioinformatics and computational biology · 100% |
Topics — the 4 heaviest of 4, each with the papers that count most for it
| Topic | Weight | Papers | Last | Evidence papers |
|---|---|---|---|---|
Bioinformatics and computational biology › biological network › network biology › network inference › gene regulatory network inference
boolean network inference |
0.1 | 1 | 2007 | Boolean dynamics of genetic regulatory networks inferred from microarray time series data · Bioinform. 2007 |
Bioinformatics and computational biology
gene expression analysis |
0.1 | 1 | 2007 | Boolean dynamics of genetic regulatory networks inferred from microarray time series data · Bioinform. 2007 |
Bioinformatics and computational biology › biological network › network biology › network inference
gene regulatory network inference |
0.1 | 1 | 2007 | Boolean dynamics of genetic regulatory networks inferred from microarray time series data · Bioinform. 2007 |
Bioinformatics and computational biology › gene expression analysis › time-series gene expression analysis
time-course microarray analysis |
0.1 | 1 | 2007 | Boolean dynamics of genetic regulatory networks inferred from microarray time series data · Bioinform. 2007 |
Methods — techniques the papers use, named apart from their topics
support vector regression · 0.1k-means clustering · 0.1
| Year | Publication | Venue | Position |
|---|---|---|---|
| 2007 | Boolean dynamics of genetic regulatory networks inferred from microarray time series dataabstractMOTIVATION: Methods available for the inference of genetic regulatory networks strive to produce a single network, usually by optimizing some quantity to fit the experimental observations. In this article we investigate the possibility that multiple networks can be inferred, all resulting in similar dynamics. This idea is motivated by theoretical work which suggests that biological networks are robust and adaptable to change, and that the overall behavior of a genetic regulatory network might be captured in terms of dynamical basins of attraction. RESULTS: We have developed and implemented a method for inferring genetic regulatory networks for time series microarray data. Our method first clusters and discretizes the gene expression data using k-means and support vector regression. We then enumerate Boolean activation-inhibition networks to match the discretized data. Finally, the dynamics of the Boolean networks are examined. We have tested our method on two immunology microarray datasets: an IL-2-stimulated T cell response dataset and a LPS-stimulated macrophage response dataset. In both cases, we discovered that many networks matched the data, and that most of these networks had similar dynamics. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Shawn Martin, Zhaoduo Zhang, Anthony Martino, Jean-Loup Faulon |
Bioinform. | 2 |