Jared Martinez

dblp:367/0022 · DBLP profile ↗
← Back
1ranked-venue papers
0as first author
1since 2021 · last 2023
—ORCID · none

Domains — the database's venue-derived domains; a paper can count in several

Applied, interdisciplinary, general and emerging computing · 1 · 1 since 2021

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
1 paper
Medical and health informatics · 100%

Topics — the 3 heaviest of 3, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Medical and health informatics › clinical diagnosis › neurodegenerative disease diagnosis
alzheimer's disease prediction
0.712023
PPAD: a deep learning architecture to predict progression of Alzheimer's disease · Bioinform. 2023
Medical and health informatics
disease progression modeling
0.712023
PPAD: a deep learning architecture to predict progression of Alzheimer's disease · Bioinform. 2023
Medical and health informatics › electronic health records
electronic health record analysis
0.712023
PPAD: a deep learning architecture to predict progression of Alzheimer's disease · Bioinform. 2023

Methods — techniques the papers use, named apart from their topics

recurrent neural network · 0.7autoencoder · 0.7
YearPublicationVenuePosition
2023 PPAD: a deep learning architecture to predict progression of Alzheimer's disease
abstract
MOTIVATION: Alzheimer's disease (AD) is a neurodegenerative disease that affects millions of people worldwide. Mild cognitive impairment (MCI) is an intermediary stage between cognitively normal state and AD. Not all people who have MCI convert to AD. The diagnosis of AD is made after significant symptoms of dementia such as short-term memory loss are already present. Since AD is currently an irreversible disease, diagnosis at the onset of the disease brings a huge burden on patients, their caregivers, and the healthcare sector. Thus, there is a crucial need to develop methods for the early prediction AD for patients who have MCI. Recurrent neural networks (RNN) have been successfully used to handle electronic health records (EHR) for predicting conversion from MCI to AD. However, RNN ignores irregular time intervals between successive events which occurs common in electronic health record data. In this study, we propose two deep learning architectures based on RNN, namely Predicting Progression of Alzheimer's Disease (PPAD) and PPAD-Autoencoder. PPAD and PPAD-Autoencoder are designed for early predicting conversion from MCI to AD at the next visit and multiple visits ahead for patients, respectively. To minimize the effect of the irregular time intervals between visits, we propose using age in each visit as an indicator of time change between successive visits. RESULTS: Our experimental results conducted on Alzheimer's Disease Neuroimaging Initiative and National Alzheimer's Coordinating Center datasets showed that our proposed models outperformed all baseline models for most prediction scenarios in terms of F2 and sensitivity. We also observed that the age feature was one of top features and was able to address irregular time interval problem. AVAILABILITY AND IMPLEMENTATION: https://github.com/bozdaglab/PPAD.
Mohammad Al Olaimat, Jared Martinez, Fahad Saeed, Serdar Bozdag
Bioinform.2