Delay/disruption-tolerant networking (DTN) is a networking technology conceived to manage opportunistic connections with no consistent end-to-end link connectivity which is common in both terrestrial and space communication environments. DTN is recognized as a baseline technology for implementing deep-space networks. Considered as the primary transport protocol of DTN in space, Licklider transmission protocol (LTP) is expected to provide reliable data delivery service in a challenging networking environment regardless of presence of random link disruptions and/or extremely long propagation delays. The National Aeronautics and Space Administration (NASA) has implemented the use of DTN protocols on the International Space Station (ISS) for data delivery to the earth ground station. However, little work has been done in studying the performance of LTP for reliable data/file delivery in such a communication environment, especially in presence of link disruption. There is a lack of a solid performance evaluation of LTP for its use in the space station communications. In this paper, an analytical framework is presented to evaluate the performance of LTP for reliable file delivery between the space station and the ground stations with a focus on the effect of link disruption, which may occur either over the downlink or over the uplink. The effect of data loss due to channel error is also integrated. Realistic data block transmission experiments using a PC-based experimental infrastructure are conducted to validate the analytical models.