Demo Data from EDBT 2026 / reviewers in the wild / expert
Oliver M. Turnbull
dblp:379/7676
· DBLP profile ↗
1ranked-venue papers
1as first author
1since 2021 · last 2024
0000-0002-0239-1207ORCID · reported
Domains — the database's venue-derived domains; a paper can count in several
Applied, interdisciplinary, general and emerging computing · 1 · 1 first-author · 1 since 2021
Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.
| Interdisciplinary, comprehensive, and emerging computing
1 paper |
Bioinformatics and computational biology · 100% |
Topics — the 2 heaviest of 2, each with the papers that count most for it
| Topic | Weight | Papers | Last | Evidence papers |
|---|---|---|---|---|
Bioinformatics and computational biology › protein design
antibody design |
0.8 | 1 | 2024 | p-IgGen: a paired antibody generative language model · Bioinform. 2024 |
Bioinformatics and computational biology
protein design |
0.8 | 1 | 2024 | p-IgGen: a paired antibody generative language model · Bioinform. 2024 |
Methods — techniques the papers use, named apart from their topics
protein language model · 0.8generative language model · 0.8fine-tuning · 0.8
| Year | Publication | Venue | Position |
|---|---|---|---|
| 2024 | p-IgGen: a paired antibody generative language modelabstractSUMMARY: A key challenge in antibody drug discovery is designing novel sequences that are free from developability issues-such as aggregation, polyspecificity, poor expression, or low solubility. Here, we present p-IgGen, a protein language model for paired heavy-light chain antibody generation. The model generates diverse, antibody-like sequences with pairing properties found in natural antibodies. We also create a finetuned version of p-IgGen that biases the model to generate antibodies with 3D biophysical properties that fall within distributions seen in clinical-stage therapeutic antibodies. AVAILABILITY AND IMPLEMENTATION: The model and inference code are freely available at www.github.com/oxpig/p-IgGen. Cleaned training data are deposited at doi.org/10.5281/zenodo.13880874. Oliver M. Turnbull, Dino Oglic, Rebecca Croasdale-Wood, Charlotte M. Deane |
Bioinform. | 1 |