Detecting and interpreting common patterns in relational data is crucial for understanding complex topological structures across various domains. These patterns, or network motifs, can often be detected algorithmically. However, visual inspection remains vital for exploring and discovering patterns. This paper focuses on presenting motifs within BioFabric network visualizations-a unique technique that opens opportunities for research on scaling to larger networks, design variations, and layout algorithms to better expose motifs. Our goal is to show how highlighting motifs can assist users in identifying and interpreting patterns in BioFabric visualizations. To this end, we leverage existing motif simplification techniques. We replace edges with glyphs representing fundamental motifs such as staircases, cliques, paths, and connector nodes. The results of our controlled experiment and usage scenarios demonstrate that motif simplification for BioFabric is useful for detecting and interpreting network patterns. Our participants were faster and more confident using the simplified view without sacrificing accuracy. The efficacy of our current motif simplification approach depends on which extant layout algorithm is used. We hope our promising findings on user performance will motivate future research on layout algorithms tailored to maximizing motif presentation. Our supplemental material is available at https://osf.io/f8s3g/?view_only=7e2df9109dfd4e6c85b89ed828320843.

Visualizing relational data is crucial for understanding complex connections between entities in social networks, political affiliations, or biological interactions. Well-known representations like node-link diagrams and adjacency matrices offer valuable insights, but their effectiveness relies on the ability to identify patterns in the underlying topological structure. Reordering strategies and layout algorithms play a vital role in the visualization process since the arrangement of nodes, edges, or cells influences the visibility of these patterns. The BioFabric visualization combines elements of node-link diagrams and adjacency matrices, leveraging the strengths of both, the visual clarity of node-link diagrams and the tabular organization of adjacency matrices. A unique characteristic of BioFabric is the possibility to reorder nodes and edges separately. This raises the question of which combination of layout algorithms best reveals certain patterns. In this paper, we discuss patterns and anti-patterns in BioFabric, such as staircases or escalators, relate them to already established patterns, and propose metrics to evaluate their quality. Based on these quality metrics, we compared combinations of well-established reordering techniques applied to BioFabric with a well-known benchmark data set. Our experiments indicate that the edge order has a stronger influence on revealing patterns than the node layout. The results show that the best combination for revealing staircases is a barycentric node layout, together with an edge order based on node indices and length. Our research contributes a first building block for many promising future research directions, which we also share and discuss. A free copy of this paper and all supplemental materials are available at https://osf.io/9mt8r/?view_only=b7t0dfbe550e3404f83059afdc60184c6.

Abstract The visual analysis of multivariate network data is a common yet difficult task in many domains. The major challenge is to visualize the network's topology and additional attributes for entities and their connections. Although node‐link diagrams and adjacency matrices are widespread, they have inherent limitations. Node‐link diagrams struggle to scale effectively, while adjacency matrices can fail to represent network topologies clearly. In this paper, we delve into the design space of BioFabric, which aligns entities along rows and relationships along columns, providing a way to encapsulate multiple attributes for both. We explore how we can leverage the unique opportunities offered by BioFabric's design space to visualize multivariate network data — focusing on three main categories: juxtaposed visualizations, embedded on‐node and on‐edge encoding, and transformed node and edge encoding. We complement our exploration with a quantitative assessment comparing BioFabric to adjacency matrices. We postulate that the expansive design possibilities introduced in BioFabric network visualization have the potential for the visualization of multivariate data, and we advocate for further evaluation of the associated design space. Our supplemental material is available on osf.io.