We present MosaicMVS, a novel learning-based depth estimation framework for a mosaic-based omnidirectional multi-view stereo (MVS) camera setup. It uses a regular field of view (FOV) MVS network for an omnidirectional imaging setup with explicit consideration of hypothetical voxel-wise FOV overlaps. The resulting depth predictions are accurate and agree on the omnidirectional multi-view geometry. Unlike existing MVS setups, MosaicMVS camera setup can be easily applied to omnidirectional indoor scenes without having to account for constraints such as intricate epipolar constraints and the distortion of omnidirectional cameras. We validate the effectiveness of our framework on a new challenging indoor dataset in terms of depth estimation, reconstruction, and view synthesis. We also present new evaluation metric to check reconstruction performance using post-processed masks for accurate evaluation without any ground truth depth map or laser-scanned reconstructions. Experimental results show that our framework outperforms the state-of-the-art MVS methods in a large margin in all test scenes.