A theorem of Matoušek asserts that for any k ≥ 2, any set system whose shatter function is o(n^k) enjoys a fractional Helly theorem of order k: in the k-wise intersection hypergraph, positive density implies a linear-size clique. Kalai and Meshulam conjectured a generalization of that phenomenon to homological shatter functions. It was verified for set systems with bounded homological shatter functions and whose ground set has a forbidden homological minor (which includes ℝ^d by a homological analogue of the van Kampen-Flores theorem). We present two contributions to this line of research: - We study homological minors in certain manifolds (possibly with boundary), for which we prove analogues of the van Kampen-Flores theorem and of the Hanani-Tutte theorem. - We introduce graded analogues of the Radon and Helly numbers of set systems and relate their growth rate to the original parameters. This allows to extend the verification of the Kalai-Meshulam conjecture to sufficiently slowly growing homological shatter functions.