Real-time multimodal inference on resource-constrained edge devices is essential for applications such as autonomous driving, human-computer interaction, and mobile health. However, prior work often overlooks the tight coupling between sensing dynamics and model execution, as well as the complex inter-modality dependencies. In this paper, we propose MMEdge, a new on-device multimodal inference framework based on pipelined sensing and encoding. Instead of waiting for complete sensor inputs, MMEdge decomposes the entire inference process into a sequence of fine-grained sensing and encoding units, allowing computation to proceed incrementally as data arrive. MMEdge also introduces a lightweight but effective temporal aggregation module that captures rich temporal dynamics across different pipelined units to maintain accuracy performance. Such pipelined design also opens up opportunities for fine-grained cross-modal optimization and early decision-making during inference. To further enhance system performance under resource variability and input data complexity, MMEdge incorporates an adaptive multimodal configuration optimizer that dynamically selects optimal sensing and model configurations for each modality under latency constraints, and a cross-modal speculative skipping mechanism that bypasses future units of slower modalities when early predictions reach sufficient confidence. We evaluate MMEdge using two public multimodal datasets and deploy it on a real-world unmanned aerial vehicle (UAV)-based multimodal testbed. The results show that MMEdge significantly reduces end-to-end latency while maintaining high task accuracy across various system and data dynamics. A video demonstration of MMEdge’s performance in real world is available at https://youtu.be/qRew7sT-iWw.

3D human pose estimation is a key enabling technology for applications such as healthcare monitoring, human-robot collaboration, and immersive gaming, but real-world deployment remains challenged by viewpoint variations. Existing methods struggle to generalize to unseen camera viewpoints, require large amounts of training data, and suffer from high inference latency. We propose MoViD, a viewpoint-invariant 3D human pose estimation framework that disentangles viewpoint information from motion features. The key idea is to extract viewpoint information from intermediate pose features and leverage it to enhance both the robustness and efficiency of pose estimation. MoViD introduces a view estimator that models key joint relationships to predict viewpoint information, and an orthogonal projection module to disentangle motion and view features, further enhanced through physics-grounded contrastive alignment across views. For real-time edge deployment, MoViD employs a frame-by-frame inference pipeline with a view-aware strategy that adaptively activates flip refinement based on the estimated viewpoint. Evaluations on nine public datasets and newly collected multiview UAV and gait analysis datasets show that MoViD reduces pose estimation error by over 24.2% compared to state-of-the-art methods, maintains robust performance under severe occlusions with 60% less training data, and achieves real-time inference at 15 FPS on NVIDIA edge devices.