Unlike discriminative approaches in autonomous driving that predict a fixed set of candidate trajectories of the ego vehicle, generative methods, such as diffusion models, learn the underlying distribution of future motion, enabling more flexible trajectory prediction. However, since these methods typically rely on denoising human-craft trajectory anchors or random noise, there remains significant room for improvement. In this paper, we propose DiffRefiner, a novel two-stage trajectory prediction framework. The first stage employs a transformer-based Proposal Decoder to generate coarse trajectory predictions by regressing from sensor inputs using predefined trajectory anchors. The second stage applies a Diffusion Refiner that iteratively denoises and refines these initial predictions. In this way, we enhance the performance of diffusion-based planning by incorporating a discriminative trajectory proposal module, which provides strong guidance for the generative refinement process. Furthermore, we design a fine-grained denoising decoder to enhance scene compliance, enabling more accurate trajectory prediction through enhanced alignment with the surrounding environment. Experimental results demonstrate that DiffRefiner achieves state-of-the-art performance, attaining 87.4 EPDMS on NAVSIM v2, and 87.1 DS along with 71.4 SR on Bench2Drive, thereby setting new records on both public benchmarks. The effectiveness of each component is validated via ablation studies as well.