Demo Data from EDBT 2026 / reviewers in the wild / expert
Davide Cesare Monti
dblp:425/2679
· DBLP profile ↗
1ranked-venue papers
0as first author
1since 2021 · last 2024
0009-0004-1710-5500ORCID · reported
Domains — the database's venue-derived domains; a paper can count in several
Applied, interdisciplinary, general and emerging computing · 1 · 1 since 2021
Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.
| Interdisciplinary, comprehensive, and emerging computing
1 paper |
Bioinformatics and computational biology · 100% |
Topics — the 4 heaviest of 4, each with the papers that count most for it
| Topic | Weight | Papers | Last | Evidence papers |
|---|---|---|---|---|
Bioinformatics and computational biology
sequence alignment |
0.8 | 1 | 2024 | RecGraph: recombination-aware alignment of sequences to variation graphs · Bioinform. 2024 |
Bioinformatics and computational biology › sequence alignment › graph-based alignment
sequence-to-graph alignment |
0.8 | 1 | 2024 | RecGraph: recombination-aware alignment of sequences to variation graphs · Bioinform. 2024 |
Bioinformatics and computational biology › comparative genomics
pangenomics |
0.2 | 1 | 2024 | RecGraph: recombination-aware alignment of sequences to variation graphs · Bioinform. 2024 |
Bioinformatics and computational biology › genomics
variation graph |
0.2 | 1 | 2024 | RecGraph: recombination-aware alignment of sequences to variation graphs · Bioinform. 2024 |
Methods — techniques the papers use, named apart from their topics
dynamic programming · 0.8
| Year | Publication | Venue | Position |
|---|---|---|---|
| 2024 | RecGraph: recombination-aware alignment of sequences to variation graphsabstractMOTIVATION: Bacterial genomes present more variability than human genomes, which requires important adjustments in computational tools that are developed for human data. In particular, bacteria exhibit a mosaic structure due to homologous recombinations, but this fact is not sufficiently captured by standard read mappers that align against linear reference genomes. The recent introduction of pangenomics provides some insights in that context, as a pangenome graph can represent the variability within a species. However, the concept of sequence-to-graph alignment that captures the presence of recombinations has not been previously investigated. RESULTS: In this paper, we present the extension of the notion of sequence-to-graph alignment to a variation graph that incorporates a recombination, so that the latter are explicitly represented and evaluated in an alignment. Moreover, we present a dynamic programming approach for the special case where there is at most a recombination-we implement this case as RecGraph. From a modelling point of view, a recombination corresponds to identifying a new path of the variation graph, where the new arc is composed of two halves, each extracted from an original path, possibly joined by a new arc. Our experiments show that RecGraph accurately aligns simulated recombinant bacterial sequences that have at most a recombination, providing evidence for the presence of recombination events. AVAILABILITY AND IMPLEMENTATION: Our implementation is open source and available at https://github.com/AlgoLab/RecGraph. Jorge Avila Cartes, Paola Bonizzoni, Simone Ciccolella, Gianluca Della Vedova, Luca Denti, Xavier Didelot, Davide Cesare Monti, Yuri Pirola |
Bioinform. | 7 |