EDBT 2026 Demo / reviewers in the wild / expert
Shangjin Han
dblp:430/4330
· DBLP profile ↗
1ranked-venue papers
1as first author
1since 2021 · last 2026
—ORCID · none
Domains — the database's venue-derived domains; a paper can count in several
Applied, interdisciplinary, general and emerging computing · 1 · 1 first-author · 1 since 2021
Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.
| Interdisciplinary, comprehensive, and emerging computing
1 paper |
Bioinformatics and computational biology · 100% |
Topics — the 2 heaviest of 2, each with the papers that count most for it
| Topic | Weight | Papers | Last | Evidence papers |
|---|---|---|---|---|
Bioinformatics and computational biology
single-cell analysis |
1.0 | 1 | 2026 | scMix: learning temporal dynamics of gene expression under irregular time intervals · Bioinform. 2026 |
Bioinformatics and computational biology › single-cell analysis
single-cell transcriptomics |
1.0 | 1 | 2026 | scMix: learning temporal dynamics of gene expression under irregular time intervals · Bioinform. 2026 |
Methods — techniques the papers use, named apart from their topics
trend regularization · 1.0receptance weighted key value architecture · 1.0language model · 1.0delta-time mechanism · 1.0
| Year | Publication | Venue | Position |
|---|---|---|---|
| 2026 | scMix: learning temporal dynamics of gene expression under irregular time intervalsabstractMOTIVATION: Understanding temporal gene expression is fundamental in the study of cellular development and differentiation. In practice, temporal single-cell datasets tend to contain only a limited number of measured time points, which are often unevenly spaced, resulting in irregular intervals between observations due to experimental constraints. Existing methods typically address these intervals by sequentially predicting one time point after another, yet lack mechanisms to explicitly model time intervals, leading to error accumulation. RESULTS: In this work, we introduce scMix, a language-model-based framework for predicting single-cell gene expression, which enables prediction from multiple historical time points. We build scMix on the Receptance Weighted Key Value architecture and use its time decay mechanism to model temporal dependencies over time. Moreover, scMix proposes a delta-time mechanism that allows the model to bypass unmeasured time points, reducing error accumulation and improving robustness. In addition, we incorporate a trend regularization strategy to enhance the temporal coherence of predicted gene expression trajectories. scMix demonstrates state-of-the-art performance in predicting gene expression at unmeasured time points, surpassing existing methods, and also achieves outstanding results on downstream tasks. AVAILABILITY AND IMPLEMENTATION: The code used for this study is available at https://doi.org/10.5281/zenodo.18287184. Shangjin Han, Dongsup Kim |
Bioinform. | 1 |