Given a spatial dataset placed on an n × n grid, our goal is to find the rectangular regions within which subsets of the dataset exhibit anomalous behavior. We develop algorithms that, given any user-supplied arbitrary likelihood function, conduct a likelihood ratio hypothesis test (LRT) over each rectangular region in the grid, rank all of the rectangles based on the computed LRT statistics, and return the top few most interesting rectangles. To speed this process, we develop methods to prune rectangles without computing their associated LRT statistics.

Given a spatial data set placed on an n x n grid, our goal is to find the rectangular regions within which subsets of the data set exhibit anomalous behavior. We develop algorithms that, given any user-supplied arbitrary likelihood function, conduct a likelihood ratio hypothesis test (LRT) over each rectangular region in the grid, rank all of the rectangles based on the computed LRT statistics, and return the top few most interesting rectangles. To speed this process, we develop methods to prune rectangles without computing their associated LRT statistics.

Classic mixture models assume that the prevalence of the various mixture components is fixed and does not vary over time. This presents problems for applications where the goal is to learn how complex data distributions evolve. We develop models and Bayesian learning algorithms for inferring the temporal trends of the components in a mixture model as a function of time. We show the utility of our models by applying them to the real-life problem of tracking changes in the rates of antibiotic resistance in Escherichia coli and Staphylococcus aureus. The results show that our methods can derive meaningful temporal antibiotic resistance patterns.