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Caroline Paccard

dblp:49/9721 · DBLP profile ↗
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1ranked-venue papers
0as first author
0since 2021 · last 2011
—ORCID · none

Domains — the database's venue-derived domains; a paper can count in several

Applied, interdisciplinary, general and emerging computing · 1

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
1 paper
Bioinformatics and computational biology · 100%

Topics — the 3 heaviest of 3, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Bioinformatics and computational biology › epigenomics › DNA methylation
DNA methylation analysis		 0.112011
SMETHILLIUM: spatial normalization METHod for ILLumina InfinIUM HumanMethylation BeadChip · Bioinform. 2011
Bioinformatics and computational biology
epigenomics		 0.112011
SMETHILLIUM: spatial normalization METHod for ILLumina InfinIUM HumanMethylation BeadChip · Bioinform. 2011
Bioinformatics and computational biology › gene expression analysis
microarray data analysis		 0.112011
SMETHILLIUM: spatial normalization METHod for ILLumina InfinIUM HumanMethylation BeadChip · Bioinform. 2011

Methods — techniques the papers use, named apart from their topics

non-parametric normalization · 0.1
YearPublicationVenuePosition
2011 SMETHILLIUM: spatial normalization METHod for ILLumina InfinIUM HumanMethylation BeadChip
abstract
SUMMARY: DNA methylation is a major epigenetic modification in human cells. Illumina HumanMethylation27 BeadChip makes it possible to quantify the methylation state of 27 578 loci spanning 14 495 genes. We developed a non-parametric normalization method to correct the spatial background noise in order to improve the signal-to-noise ratio. The prediction performance of the proposed method was assessed on three fully methylated samples and three fully unmethylated DNA samples. We demonstrate that the spatial normalization outperforms BeadStudio to predict the methylation state of a given locus. AVAILABILITY AND IMPLEMENTATION: A R script and the data are available at the following address: http://bioinfo.curie.fr/projects/smethillium.
Camille Sabbah, Gildas Mazo, Caroline Paccard, Fabien Reyal, Philippe Hupé
 Bioinform.3