Robotic manipulation based on visual observations and natural language instructions is a long-standing challenge in robotics. Yet prevailing approaches model action distribution by adopting explicit or implicit representations, which often struggle to achieve a trade-off between accuracy and efficiency. In response, we propose PDFactor, a novel framework that models action distribution with a hybrid triplane representation. In particular, PDFactor decomposes 3D point cloud into three orthogonal feature planes and leverages a tri-perspective view transformer to produce dense cubic features as a latent diffusion field aligned with observation space representing 6-DoF action probability distribution at an arbitrary location. We employ a small denoising network conceptually as both a parameterized loss function measuring the quality of the learned latent features and an action gradient decoder to sample actions from the latent diffusion field during inference. This design enables our PDFactor to benefit from spatial awareness of explicit representation and arbitrary resolution of implicit representation, rendering it with manipulation accuracy, inference efficiency, and model scalability. Experiments demonstrate that PDFactor outperforms state-of-the-art approaches across a diverse range of manipulation tasks in RLBench simulation. Moreover, PDFactor can effectively learn multi-task policies from a limited number of human demonstrations, achieving promising accuracy in a variety of real-world manipulation tasks.

Robotic manipulation in high-precision tasks is essential for numerous industrial and real-world applications where accuracy and speed are required. Yet current diffusion-based policy learning methods generally suffer from low computational efficiency due to the iterative denoising process during inference. Moreover, these methods do not fully explore the potential of generative models for enhancing information exploration in 3D environments. In response, we propose FlowRAM, a novel framework that leverages generative models to achieve region-aware perception, enabling efficient multimodal information processing. Specifically, we devise a Dynamic Radius Schedule, which allows adaptive perception, facilitating transitions from global scene comprehension to fine-grained geometric details. Furthermore, we integrate state space models to integrate multimodal information, while preserving linear computational complexity. In addition, we employ conditional flow matching to learn action poses by regressing deterministic vector fields, simplifying the learning process while maintaining performance. We verify the effectiveness of the FlowRAM in the RLBench, an established manipulation benchmark, and achieve state-of-the-art performance. The results demonstrate that FlowRAM achieves a remarkable improvement, particularly in high-precision tasks, where it outperforms previous methods by 12.0% in average success rate. Additionally, FlowRAM is able to generate physically plausible actions for a variety of real-world tasks in less than 4 time steps, significantly increasing inference speed.

Embodied localization based on vision and natural language dialogues presents a persistent challenge in embodied intelligence. Existing methods often approach this task as an image translation problem, leveraging encoder-decoder architectures to predict heatmaps. However, these methods frequently experience a deficiency in accuracy, largely due to their heavy reliance on resolution. To address this issue, we introduce CGD, a novel framework that utilizes causality guided diffusion model to directly model coordinate distributions. Specifically, CGD employs a denoising network to regress coordinates, while integrating causal learning modules, namely back-door adjustment (BDA) and front-door adjustment (FDA) to mitigate confounders during the diffusion process. This approach reduces the dependency on high resolution for improving accuracy, while effectively minimizing spurious correlations, thereby promoting unbiased learning. By guiding the denoising process with causal adjustments, CGD offers flexible control over intensity, ensuring seamless integration with diffusion models. Experimental results demonstrate that CGD outperforms state-of-the-art methods across all metrics. Additionally, we also evaluate CGD in a multi-shot setting, achieving consistently high accuracy.

Learning generalizable robotic manipulation policies remains a key challenge due to the scarcity of diverse real-world training data. While recent approaches have attempted to mitigate this through self-supervised representation learning, most either rely on 2D vision pretraining paradigms such as masked image modeling, which primarily focus on static semantics or scene geometry, or utilize large-scale video prediction models that emphasize 2D dynamics, thus failing to jointly learn the geometry, semantics, and dynamics required for effective manipulation. In this paper, we present DynaRend, a representation learning framework that learns 3D-aware and dynamics-informed triplane features via masked reconstruction and future prediction using differentiable volumetric rendering. By pretraining on multi-view RGB-D video data, DynaRend jointly captures spatial geometry, future dynamics, and task semantics in a unified triplane representation. The learned representations can be effectively transferred to downstream robotic manipulation tasks via action value map prediction. We evaluate DynaRend on two challenging benchmarks, RLBench and Colosseum, as well as in real-world robotic experiments, demonstrating substantial improvements in policy success rate, generalization to environmental perturbations, and real-world applicability across diverse manipulation tasks.

World models allow agents to simulate the consequences of actions in imagined environments for planning, control, and long-horizon decision-making. However, existing autoregressive world models struggle with visually coherent predictions due to disrupted spatial structure, inefficient decoding, and inadequate motion modeling. In response, we propose Scale-wise Autoregression with Motion PrOmpt (SAMPO), a hybrid framework that combines visual autoregressive modeling for intra-frame generation with causal modeling for next-frame generation. Specifically, SAMPO integrates temporal causal decoding with bidirectional spatial attention, which preserves spatial locality and supports parallel decoding within each scale. This design significantly enhances both temporal consistency and rollout efficiency. To further improve dynamic scene understanding, we devise an asymmetric multi-scale tokenizer that preserves spatial details in observed frames and extracts compact dynamic representations for future frames, optimizing both memory usage and model performance. Additionally, we introduce a trajectory-aware motion prompt module that injects spatiotemporal cues about object and robot trajectories, focusing attention on dynamic regions and improving temporal consistency and physical realism. Extensive experiments show that SAMPO achieves competitive performance in action-conditioned video prediction and model-based control, improving generation quality with 4.4× faster inference. We also evaluate SAMPO's zero-shot generalization and scaling behavior, demonstrating its ability to generalize to unseen tasks and benefit from larger model sizes.

Colorectal cancer (CRC) is one of the most common gastrointestinal malignancies. There are few recurrence risk signatures for CRC patients. Single-cell RNA-sequencing (scRNA-seq) provides a high-resolution platform for prognostic signature detection. However, scRNA-seq is not practical in large cohorts due to its high cost and most single-cell experiments lack clinical phenotype information. Few studies have been reported to use external bulk transcriptome with survival time to guide the detection of key cell subtypes in scRNA-seq data. We proposed scRankXMBD, a computational framework to prioritize prognostic-associated cell subpopulations based on within-cell relative expression orderings of gene pairs from single-cell transcriptomes. scRankXMBD achieves higher precision and concordance compared with five existing methods. Moreover, we developed single-cell gene pair signatures to predict recurrence risk for patients individually. Our work facilitates the application of the rank-based method in scRNA-seq data for prognostic biomarker discovery and precision oncology. scRankXMBD is available at https://github.com/xmuyulab/scRank-XMBD. (XMBD:Xiamen Big Data, a biomedical open software initiative in the National Institute for Data Science in Health and Medicine, Xiamen University, China.).