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Walter Gilbert

dblp:60/6904 · DBLP profile ↗
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1ranked-venue papers
1as first author
0since 2021 · last 2000
—ORCID · none

Domains — the database's venue-derived domains; a paper can count in several

Applied, interdisciplinary, general and emerging computing · 1 · 1 first-author

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
1 paper
Bioinformatics and computational biology · 100%

Topics — the 1 heaviest of 2, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Bioinformatics and computational biology › molecular evolution › evolutionary bioinformatics
evolutionary genomics
0.012000
Invited presentation: introns and modules in ancient conserved genes (abstract only) · RECOMB 2000

Methods — techniques the papers use, named apart from their topics

structural analysis · 0.0phylogenetic comparison · 0.0
YearPublicationVenuePosition
2000 Invited presentation: introns and modules in ancient conserved genes (abstract only)
abstract
We study the correlation between introns and modules, compact regions of protein structure, in genes whose products have a known 3-dimensional structre and which are homologous between bacteria and eukaryotes. Using two definitions of modules, we show that phase zero introns, those that lie between the codons, are significantly correlated with the boundaries of modules while introns that lie in phases one and two, that interrupt the codons are not so correlated. Furthermore, intron positions that are philogenetically ancient, matching between two kingdomes, are more correlated with module boundaries than are other positions. We will discuss the significance of these findings, which suggest that some of the phase zero introns are residues of the original construction of the genes while the phase one and two introns may have been added later in evolution.
Walter Gilbert
RECOMB1