In current wireless base station solutions it is becoming common to physically separate baseband units and radio subsystems. In many wireless technologies this architecture requires allocation of significant transport network resources. In this paper a low-latency baseband signal compression scheme is presented. The compression scheme significantly lowers the transport data rate while maintaining low levels of signal distortion, thus resulting in a lower-cost transport network. Considering the importance of packet-based networks, a number of additional novel compression schemes are proposed. They are optimized for transport networks that implement a quality-of-service (QoS) mechanism and/or multi-link transmission. The compression schemes are parameterized such that a smooth trade-off between the required signal quality and compression performance can be achieved through operator choice of the suitable parameter values. An attractive feature of these schemes is that they can be applied to different wireless technologies, with appropriate parameter settings, without disrupting the present architecture. The proposed solutions will lead to a cost-effective implementation of collocated and distributed network-centric baseband processing, coordinated multi-point (CoMP) and/or distributed antenna system (DAS) which are critical topics for the entire wireless telecommunications industry and infrastructure.

Background Early detection of autism can improve the quality of life of affected individuals [1]. Qualitative screening methods continue to improve, but still suffer from low sensitivity despite increasing specificity [2,3]. In collaboration with the Hospital for Sick Children, we are sequencing the exomes of 1 000 individuals with autism in order to discover genetic variants associated with the disorder. Discovery of associated variants can lead to earlier diagnosis and treatment.

In this paper, a multiple-input-multiple-output (MIMO) extension for a third-generation (3G) wireless system is described. The integration of MIMO concepts within the existing UMTS standard and the associated space-time RAKE receiver are explained. An analysis is followed by a description of an actual experimental MIMO transmitter and receiver architecture, both realized on digital signal processors (DSPs) and FPGAs within a precommercial OneBTS base station. It uses four transmit and four receive antennas to achieve downlink data rates up to 1 Mb/s per user with a spreading factor of 32 and the UMTS chip rate of 3.84 MHz. Furthermore, different MIMO detectors are evaluated, comparing their performance and complexity. System performance is evaluated through simulations and indoor over-the-air measurements. Capacity and bit-error rate measurement results are presented.